Most Cited Articles
Most Cited Articles
Original Article with more than 100 citations where CIC bioGUNE group leader appears
as senior researcher and/or corresponding author. Listed as number of citation per year based on Web of Science database.
Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes
Juan Manuel Falcón
Exosomal membrane proteins as interesting tool to express nonexosomal proteins into exosomes with therapeutic purposes.
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
José M Mato
We identified specific panels of markers that could distinguish patients with NASH from patients with simple steatosis for each subtype of NAFLD.
Sox2 promotes tamoxifen resistance in breast cancer cells
María Vivanco
Development of tamoxifen resistance is driven by Sox2‐dependent activation of Wnt signalling in cancer stem/progenitor cells.
Selected for Cover
Ana M Aransay
Stand-alone version of the miRanalyzer that is based on a local and easily customized database is also available at https://bioinfo5.ugr.es/srnatoolbox/
MiRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments
Ana M Aransay
The web tool provides a comprehensive overview of microRNA analysis.
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice
José M Mato
Methylation of RASSF1 and SOCS2 promoters and the binding of trimethylated lysine 27 in histone 3 to these 2 genes was increased in Hepatocellular Cacinomas from GNMT-KO mice
Obesity-Dependent Metabolic Signatures Associated with Nonalcoholic Fatty Liver Disease Progression
José M Mato
BMI-dependent serum metabolic profile may be able to reliably distinguish NASH from steatosis patients, have significant implications for the development of NASH biomarkers.
Quaternary structures of tumor suppressor p53 and a specific p53-DNA complex
Mikel Valle
The structure of the DNA complex is consistent with that of the complex of four separate core domains and response element fragments solved by x-ray crystallography and contacts identified by NMR
Structure of ratcheted ribosomes with tRNAs in hybrid states
Mikel Valle
During protein synthesis, the displacement of the A-site tRNA on the 50S subunit is passive and is induced by the 30S subunit rotation, catalyzed by elongation factor G.
José M Mato
Metabolic phenotyping approach may have a future role as a supplement for clinical decision making in NAFLD and in the adaption to more individualized treatment protocols.