Publications

2023

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations
Thomas, M; Su, YR; Rosenthal, EA; Sakoda, LC; Schmit, SL; Timofeeva, MN; Chen, Z; Fernandez-Rozadilla, C; Law, PJ; Murphy, N; Carreras-Torres, R; Diez-Obrero, V; van Duijnhoven, FJB; Jiang, ...
NATURE COMMUNICATIONS
2023

Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
Gonzalez-Rellan, MJ; Fernández, U; Parracho, T; Novoa, E; Fondevila, MF; Lima, ND; Ramos, L; Rodríguez, A; Serrano-Maciá, M; Perez-Mejias, G; Chantada-Vazquez, P; Riobello, C; Veyrat-Durebex, ...
CELL METABOLISM
2023

A pilot genome-wide association study meta-analysis of gastroparesis
Tavares, LC; Zheng, TH; Kwicklis, M; Mitchell, E; Pandit, A; Pullapantula, S; Bernard, C; Teder-Laving, M; Marques, FZ; Esko, T; Kuo, BD; Shulman, RJ; Chumpitazi, BP; Koch, KL; Sarosiek, I; ...
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
2023

A tetracationic porphyrin with dual anti-prion activity
Masone, A; Zucchelli, C; Caruso, E; Lavigna, G; Eraña, H; Giachin, G; Tapella, L; Comerio, L; Restelli, E; Raimondi, I; Elezgarai, SR; De Leo, F; Quilici, G; Taiarol, L; Oldrati, M; Lorenzo, ...
ISCIENCE
2023

Key substrate recognition residues in the active site of cystathionine beta-synthase from Toxoplasma gondii
Conter, C; Favretto, F; Dominici, P; Martinez-Cruz, LA; Astegno, A;
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
2023

Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma
Espinosa-Sotelo, R; Fusté, NP; Peñuelas-Haro, I; Alay, A; Pons, G; Almodóvar, X; Albaladejo, J; Sánchez-Vera, I; Bonilla-Amadeo, R; Dituri, F; Serino, G; Ramos, E; Serrano, T; Calvo, M; Martínez-Chantar, ...
REDOX BIOLOGY
2023

Spatial metabolomics and its application in the liver
Santos, AA; Delgado, TC; Marques, V; Ramirez-Moncayo, C; Alonso, C; Vidal-Puig, A; Hall, Z; Martínez-Chantar, ML; Rodrigues, CMP;
HEPATOLOGY
2023

Harnessing deep learning for population genetic inference
Huang, X; Rymbekova, A; Dolgova, O; Lao, OS; Kuhlwilm, M;
NATURE REVIEWS GENETICS
2023

Exploring multivalent carbohydrate-protein interactions by NMR
Quintana, JI; Atxabal, U; Unione, L; Ardá, A; Jiménez-Barbero, J;
CHEMICAL SOCIETY REVIEWS
2023

SARS-CoV-2 Spike N-Terminal Domain Engages 9-O-Acetylated?2-8-Linked Sialic Acids
Tomris, I; Unione, L; Nguyen, L; Zaree, P; Bouwman, KM; Liu, L; Li, ZS; Fok, JA; Carrasco, MR; van der Woude, R; Kimpel, ALM; Linthorst, MW; Kilavuzoglu, SE; Verpalen, ECJM; Caniels, TG; Sanders, ...
ACS CHEMICAL BIOLOGY
2023

Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study
Constantinescu, AE; Bull, CJ; Jones, N; Mitchell, R; Burrows, K; Dimou, N; Bézieau, S; Brenner, H; Buchanan, DD; DAmato, M; Jenkins, MA; Moreno, V; Pai, RK; Um, CY; White, E; Murphy, N; Gunter, ...
INTERNATIONAL JOURNAL OF CANCER
2023

Ghost admixture in eastern gorillas
Pawar, H; Rymbekova, A; Cuadros-Espinoza, S; Huang, X; de Manuel, M; van der Valk, T; Lobon, I; Alvarez-Estape, M; Haber, M; Dolgova, O; Han, SJ; Esteller-Cucala, P; Juan, DV; Ayub, Q; Bautista, ...
NATURE ECOLOGY & EVOLUTION
2023

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b
Lenza, MP; Egia-Mendikute, L; Antoñana-Vildosola, A; Soares, CO; Coelho, H; Corzana, F; Bosch, A; Manisha, P; Quintana, JI; Oyenarte, I; Unione, L; Moure, MJ; Azkargorta, M; Atxabal, U; Sobczak, ...
NATURE COMMUNICATIONS
2023

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Pencik, J; Philippe, C; Schlederer, M; Atas, E; Pecoraro, M; Grund-Gröchke, S; Li, W; Tracz, A; Heidegger, I; Lagger, S; Trachtová, K; Oberhuber, M; Heitzer, E; Aksoy, O; Neubauer, HA; Wingelhofer, ...
MOLECULAR CANCER
2023

Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
Pena-Cearra, A; Song, DG; Castelo, J; Palacios, A; Lavin, JL; Azkargorta, M; Elortza, F; Fuertes, M; Pascual-Itoiz, MA; Barriales, D; Martin-Ruiz, I; Fullaondo, A; Aransay, AM; Rodriguez, H; ...
NPJ BIOFILMS AND MICROBIOMES
2023

Ratiometric Fluorescent Sensors Illuminate Cellular Magnesium Imbalance in a Model of Acetaminophen-Induced Liver Injury
Brady, M; Shchepetkina, VI; González-Recio, I; Martínez-Chantar, ML; Buccella, D;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2023

Controlling the protein corona of polymeric nanocapsules: effect of polymer shell on protein adsorption
Berrecoso, G; Bravo, SB; Arriaga, I; Abrescia, N; Crecente-Campo, J; Alonso, MJ;
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
2023

An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein
Vanni, I; Iacobone, F; DAgostino, C; Giovannelli, M; Pirisinu, L; Altmeppen, HC; Castilla, J; Torres, JM; Agrimi, U; Nonno, R;
JOURNAL OF BIOLOGICAL CHEMISTRY
2023

A novel diagnostic serum protein signature for paediatric Inflammatory Bowel Disease: A discovery and validation study in two independent inception cohorts
Mathisen, CBW; Nyström, N; Bazov, I; Andersen, S; Olbjorn, C; Perminow, G; Kristensen, VA; Opheim, R; Ricanek, P; DAmato, M; Carlson, M; Hedin, CR; Keita, AV; Kruse, R; Lindqvist, CM; Magnusson, ...
JOURNAL OF CROHNS & COLITIS
2023

Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development
Rana, VS; Kitsou, C; Dutta, S; Ronzetti, MH; Zhang, M; Bernard, Q; Smith, AA; Tomás-Cortázar, J; Yang, XL; Wu, MJ; Kepple, O; Li, WZ; Dwyer, JE; Matias, J; Baljinnyam, B; Oliver, JD; Rajeevan, ...
SCIENCE
2023

Expanding the Substrate Scope of Acyltransferase LovD9 for the Biosynthesis of Statin Analogues
García-Marquina, G; Núñez-Franco, R; Grajales-Hernández, D; Jiménez-Osés, G; López-Gallego, F;
CHEMISTRY-A EUROPEAN JOURNAL
2023

Dual-Wave Acoustofluidic Centrifuge for Ultrafast Concentration of Nanoparticles and Extracellular Vesicles
Dumcius, P; Mikhaylov, R; Zhang, XY; Bareford, M; Stringer, M; Errington, R; Sun, C; Gonzalez, E; Krukovski, T; Falcon-Perez, JM; Liang, DF; Fu, YQ; Clayton, A; Yang, X;
SMALL
2023

Feasibility, safety, and outcome of second-line nivolumab/bevacizumab in liver transplant patients with recurrent hepatocellular carcinoma
Di Marco, L; Pivetti, A; Foschi, FG; DAmico, R; Schepis, F; Caporali, C; Casari, F; Lasagni, S; Critelli, RM; Milosa, F; Romanzi, A; Marcelli, G; De Maria, N; Romagnoli, D; Catellani, B; Sciano, ...
LIVER TRANSPLANTATION
2023

A single cell-based computational platform to identify chemical compounds targeting desired sets of transcription factors for cellular conversion
Zheng, ML; Xie, BQ; Okawa, S; Liew, SY; Deng, HK; del Sol, A;
STEM CELL REPORTS
2023

Transcriptional and Chromatin Accessibility Profiling of Neural Stem Cells Differentiating into Astrocytes Reveal Dynamic Signatures Affected under Inflammatory Conditions
Pavlou, MAS; Singh, K; Ravichandran, S; Halder, R; Nicot, N; Birck, C; Grandbarbe, L; del Sol, A; Michelucci, A;
CELLS
2023

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants
Romerio, A; Gotri, N; Franco, AR; Artusa, V; Shaik, MM; Pasco, ST; Atxabal, U; Matamoros-Recio, A; Mínguez-Toral, M; Zalamea, JD; Franconetti, A; Abrescia, NGA; Jimenez-Barbero, J; Anguita, ...
JOURNAL OF MEDICINAL CHEMISTRY
2023

Intravital imaging of Wnt/?-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis
Stoletov, K; Sanchez, S; Gorroño, I; Rabano, M; Vivanco, MDM; Kypta, R; Lewis, JD;
JOURNAL OF CELL SCIENCE
2023

Sucrase-isomaltase genotype and response to a starch-reduced and sucrose-reduced diet in IBS-D patients
Zamfir-Taranu, A; Löcher, BS; Husein, DM; Hoter, A; Garcia-Etxebarria, K; Etxeberria, U; Gayoso, L; Mayr, G; Nilholm, C; Gustafsson, RJ; Ozaydin, O; Zheng, TH; Esteban-Blanco, C; Bozzarelli, ...
GUT
2023

Measuring biological age using a functionally interpretable multi-tissue RNA clock
Jung, SS; Hodar, JA; del Sol, A;
AGING CELL
2023

Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening
Mazo, N; Rahman, IR; Navo, CD; Peregrina, JM; Busto, JH; van der Donk, WA; Jiménez-Osés, G;
ORGANIC LETTERS
2023

Turning universal O into rare Bombay type blood
Anso, I; Naegeli, A; Cifuente, JO; Orrantia, A; Andersson, E; Zenarruzabeitia, O; Moraleda-Montoya, A; Garcia-Alija, M; Corzana, F; Del Orbe, RA; Borrego, F; Trastoy, B; Sjögren, J; Guerin, ME;
NATURE COMMUNICATIONS
2023

A Novel Approach on the Use of Samples from Faecal Occult Blood Screening Kits for Metabolomics Analysis: Application in Colorectal Cancer Population
Albóniga, OE; Cubiella, J; Bujanda, L; Blanco, ME; Lanza, BR; Alonso, C; Nafría, B; Falcón-Péerez, JM;
METABOLITES
2023

Molecular dynamics simulations reveal the impact of NUDT15 R139C and R139H variants in structural conformation and dynamics
Gómez-Rubio, E; Garcia-Marin, J;
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
2023

Metabolic Features of Increased Gut Permeability, Inflammation, and Altered Energy Metabolism Distinguish Agricultural Workers at Risk for Mesoamerican Nephropathy
Raines, NH; Leone, DA; OCallaghan-Gordo, C; Ramirez-Rubio, O; Amador, JJ; Pilarte, DL; Delgado, IS; Leibler, JH; Embade, N; Gil-Redondo, R; Bruzzone, C; Bizkarguenaga, M; Scammell, MK; Parikh, ...
METABOLITES
2023

Development of synthetic, self-adjuvanting, and self-assembling anticancer vaccines based on a minimal saponin adjuvant and the tumor-associated MUC1 antigen
Pifferi, C; Aguinagalde, L; Ruiz-de-Angulo, A; Sacristán, N; Baschirotto, PT; Poveda, A; Jiménez-Barbero, J; Anguita, J; Fernández-Tejada, A;
CHEMICAL SCIENCE
2023

Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes
Cano, A; Vazquez-Chantada, M; Conde-Vancells, J; Gonzalez-Lahera, A; Mosen-Ansorena, D; Blanco, FJ; Clément, K; Aron-Wisnewsky, J; Tran, A; Gual, P; García-Monzón, C; Caballería, J; Castro, ...
BIOMEDICINES
2023

Redox regulation of KV7 channels through EF3 hand of calmodulin
Nunez, E; Jones, F; Muguruza-Montero, A; Urrutia, J; Aguado, A; Malo, C; Bernardo-Seisdedos, G; Domene, C; Millet, O; Gamper, N; Villarroel, A; Colecraft, HM;
ELIFE
2023

Revealing the Specificity of Human H1 Influenza A Viruses to Complex N-Glycans
Canales, A; Sastre, J; Orduña, JM; Spruit, CM; Pérez-Castells, J; Domínguez, G; Bouwman, KM; van der Woude, R; Cañada, FJ; Nycholat, CM; Paulson, JC; Boons, GJ; Jiménez-Barbero, J; de Vries, RP;
JACS AU
2023

Biomimetic Tweezers for N-Glycans: Selective Recognition of the Core GlcNAc2 Disaccharide of the Sialylglycopeptide SGP
Milanesi, F; Unione, L; Ardá, A; Nativi, C; Jiménez-Barbero, J; Roelens, S; Francesconi, O;
CHEMISTRY-A EUROPEAN JOURNAL
2023

Effect of ATG12-ATG5-ATG16L1 autophagy E3-like complex on the ability of LC3/GABARAP proteins to induce vesicle tethering and fusion
Iriondo, MN; Etxaniz, A; Varela, YR; Ballesteros, U; Lázaro, M; Valle, M; Fracchiolla, D; Martens, S; Montes, LR; Goñi, FM; Alonso, A;
CELLULAR AND MOLECULAR LIFE SCIENCES
2023

Chemical biology tools to interrogate the roles of O-GlcNAc in immunity
Saha, A; Fernández-Tejada, A;
FRONTIERS IN IMMUNOLOGY
2023

Identifying prognostic parameters related to surgical technique in patients treated by robotic radical prostatectomy
Iriarte, AL; Viscasillas, IL; Gonzalez, SR; Martín, AS; Aparicio, DG; Olano, AU; Pérez, AC; Urzaiz, MU;
ACTAS UROLOGICAS ESPANOLAS
2023

Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles
Peccati, F; Alunno-Rufini, S; Jiménez-Osés, G;
JOURNAL OF CHEMICAL INFORMATION AND MODELING
2023

Iridium-Catalyzed ortho-Selective Borylation of Aromatic Amides Enabled by 5-Trifluoromethylated Bipyridine Ligands
Marcos-Atanes, D; Vidal, C; Navo, CD; Peccati, F; Jiménez-Osés, G; Mascareñas, JL;
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2023

Compliant mechanical response of the ultrafast folding protein EnHD under force
Reifs, A; Ortiz, IR; Saa, AO; Schönfelder, J; De Sancho, D; Muñoz, V; Perez-Jimenez, R;
COMMUNICATIONS PHYSICS
2023

Application of self-organizing maps to AFM-based viscoelastic characterization of breast cancer cell mechanics
Weber, A; Vivanco, MDM; Toca-Herrera, JL;
SCIENTIFIC REPORTS
2023

Structural basis of the inhibition of cystathionine gamma-lyase from Toxoplasma gondii by propargylglycine and cysteine
Fernandez-Rodriguez, C; Conter, C; Oyenarte, I; Favretto, F; Quintana, I; Martinez-Chantar, ML; Astegno, A; Martinez-Cruz, LA;
PROTEIN SCIENCE
2023

Epi-Impute: Single-Cell RNA-seq Imputation via Integration with Single-Cell ATAC-seq
Raevskiy, M; Yanvarev, V; Jung, SS; Del Sol, A; Medvedeva, YA;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

The Ixodes ricinus salivary gland proteome during feeding and B. Afzelii infection: New avenues for an anti-tick vaccine
Klouwens, MJ; Trentelman, JJA; Barriales, D; Ersoz, JI; Azkargorta, M; Elortza, F; Síma, R; Hajdusek, O; Cortazar, JT; Corcuera, IE; Colstrup, E; Nayak, A; Ruíz, IM; Rodriguez, H; Nijhof, AM; ...
VACCINE
2023

Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
Bruzzone, C; Conde, R; Embade, N; Mato, JM; Millet, O;
FRONTIERS IN MOLECULAR BIOSCIENCES
2023

The effect of starch- and sucrose-reduced diet accompanied by nutritional and culinary recommendations on the symptoms of irritable bowel syndrome patients with diarrhoea
Gayoso, L; Garcia-Etxebarria, K; Arzallus, T; Montalvo, I; Lizasoain, J; DAmato, M; Etxeberria, U; Bujanda, L;
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
2023

Structural basis of the inhibition of cystathionine γ-lyase from Toxoplasma gondii by propargylglycine and cysteine
Fernández-Rodríguez, C; Conter, C; Oyenarte, I; Favretto, F; Quintana, I; Martinez-Chantar, ML; Astegno, A; Martínez-Cruz, LA;
PROTEIN SCIENCE
2023

Dynamin-like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis
Gupta, S; Bhagavathula, M; Sharma, V; Sharma, N; Sharma, N; Biswas, A; Palacios, A; Salgueiro, V; Lavín, JL; Dogra, N; Salgame, P; Prados-Rosales, R; Rodríguez, GM;
EMBO REPORTS
2023

Protoporphyrin IX Binds to Iron(II)-Loaded and to Zinc-Loaded Human Frataxin
Bernardo-Seisdedos, G; Schedlbauer, A; Pereira-Ortuzar, T; Mato, JM; Millet, O;
LIFE-BASEL
2023

Highly Diastereoselective Multicomponent Synthesis of Spirocyclopropyl Oxindoles Enabled by Rare-Earth Metal Salts
Tallarida, MA; Olivito, F; Navo, CD; Algieri, V; Jiritano, A; Costanzo, P; Poveda, A; Moure, MJ; Jiménez-Barbero, J; Maiuolo, L; Jiménez-Osés, G; De Nino, A;
ORGANIC LETTERS
2023

Machine Learning-Assisted High-Throughput SERS Classification of Cell Secretomes
Plou, J; Valera, PS; García, I; Vila-Liarte, D; Renero-Lecuna, C; Ruiz-Cabello, J; Carracedo, A; Liz-Marzán, LM;
SMALL
2023

Molecular Recognition of Glycan-Bearing Glycomacromolecules Presented at Membrane Surfaces by Lectins: An NMR View
Lete, MG; Hoffmann, M; Schomann, N; Martínez-Castillo, A; Peccati, F; Konietzny, PB; Delgado, S; Snyder, NL; Jiménez-Oses, G; Abrescia, NGA; Ardá, A; Hartmann, L; Jiménez-Barbero, J;
ACS OMEGA
2023

On the Rational Design of Cooperative Receptors
Ortega, G; Chamorro-Garcia, A; Ricci, F; Plaxco, KW;
ANNUAL REVIEW OF BIOPHYSICS
2023

Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C-C Bond Cleavage Reactions
Dal Forno, GM; Latocheski, E; Machado, AB; Becher, J; Dunsmore, L; St John, AL; Oliveira, BL; Navo, CD; Jiménez-Osés, G; Fior, R; Domingos, JB; Bernardes, GJL;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2023

Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR-/- mice
Guerra, GS; Barriales, D; Lorenzo, G; Moreno, S; Anguita, J; Brun, A; Abrescia, NGA;
VACCINE
2023

Research Priorities for Precision Medicine in NAFLD
Iruzubieta, P; Bataller, R; Arias-Loste, MT; Arrese, M; Calleja, JL; Castro-Narro, G; Cusi, K; Dillon, JF; Martínez-Chantar, ML; Mateo, M; Pérez, A; Rinella, ME; Romero-Gómez, M; Schattenberg, ...
CLINICS IN LIVER DISEASE
2023

Production of neutralizing antibody fragment variants in the cytoplasm of E. coli for rapid screening: SARS-CoV-2 a case study
Tungekar, AA; Recacha, R; Ruddock, LW;
SCIENTIFIC REPORTS
2023

A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule
Cifuente, JO; Schulze, J; Bethe, A; Di Domenico, V; Litschko, C; Budde, I; Eidenberger, L; Thiesler, H; Roth, IR; Berger, M; Claus, H; DAngelo, C; Marina, A; Gerardy-Schahn, R; Schubert, M; ...
NATURE CHEMICAL BIOLOGY
2023

Recent Advances and Potential Multi-Omics Approaches in the Early Phases of Inflammatory Bowel Disease
Rodríguez-Lago, I; Blackwell, J; Mateos, B; Marigorta, UM; Barreiro-de Acosta, M; Pollok, R;
JOURNAL OF CLINICAL MEDICINE
2023

Hyperphosphorylation of hepatic proteome characterizes nonalcoholic fatty liver disease in S-adenosylmethionine deficiency
Robinson, AE; Binek, A; Ramani, K; Sundararaman, N; Barbier-Torres, L; Murray, B; Venkatraman, V; Kreimer, S; Mc Ardle, A; Noureddin, M; Fernandez-Ramos, D; Lopitz-Otsoa, F; de Juan, VG; Millet, ...
iScience
2023

Application of self-organizing maps to AFM-based viscoelastic characterization of breast cancer cell mechanics
Weber, A; Vivanco, MDM; Toca-Herrera, JL;
Scientific Reports
2023

Structural analysis of ING3 protein and histone H3 binding
Ferreras-Gutiérrez, M; Chaves-Arquero, B; González-Magaña, A; Merino, N; Amusategui-Mateu, I; Huecas, S; Medrano, FJ; Blanco, FJ;
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
2023

Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol-Gel Coating
Cerqueira, A; Romero-Gavilan, F; Helmholz, H; Azkargorta, M; Elortza, F; Gurruchaga, M; Goni, I; Willumeit-Romer, R; Suay, J;
ACS BIOMATERIALS SCIENCE & ENGINEERING
2023

Tcf20 deficiency is associated with increased liver fibrogenesis and alterations in mitochondrial metabolism in mice and humans
Córdoba-Jover, B; Ribera, J; Portolés, I; Lecue, E; Rodriguez-Vita, J; Pérez-Sisqués, L; Mannara, F; Solsona-Vilarrasa, E; García-Ruiz, C; Fernández-Checa, JC; Casals, G; Rodríguez-Revenga, ...
LIVER INTERNATIONAL
2023

Potential Role of the mTORC1-PGC1α-PPARα Axis under Type-II Diabetes and Hypertension in the Human Heart
Hang, TY; Lumpuy-Castillo, J; Goikoetxea-Usandizaga, N; Azkargorta, M; Aldámiz, G; Martínez-Milla, J; Forteza, A; Cortina, JM; Egido, J; Elortza, F; Martínez-Chantar, M; Tuñón, J; Lorenzo, O;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Tuberous Sclerosis Complex cell-derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers
Bhaoighill, MN; Falcón-Pérez, JM; Royo, F; Tee, AR; Webber, JP; Dunlop, EA;
JOURNAL OF EXTRACELLULAR VESICLES
2023

Total Synthesis and Structural Studies of Zwitterionic Bacteroides fragilis Polysaccharide A1 Fragments
Wang, Z; Poveda, A; Zhang, QJ; Unione, L; Overkleeft, HS; van der Marel, GA; Jesús, JB; Codée, JDC;
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2023

DNA Polymerases for Whole Genome Amplification: Considerations and Future Directions
Ordóñez, CD; Redrejo-Rodríguez, M;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Architecture of the ESCPE-1 membrane coat
Lopez-Robles, C; Scaramuzza, S; Astorga-Simon, EN; Ishida, M; Williamson, CD; Baños-Mateos, S; Gil-Carton, D; Romero-Durana, M; Vidaurrazaga, A; Fernandez-Recio, J; Rojas, AL; Bonifacino, JS; ...
NATURE STRUCTURAL & MOLECULAR BIOLOGY
2023

KR-12 Derivatives Endow Nanocellulose with Antibacterial and Anti-Inflammatory Properties: Role of Conjugation Chemistry
Blasi-Romero, A; Angström, M; Franconetti, A; Muhammad, T; Jiménez-Barbero, J; Göransson, U; Palo-Nieto, C; Ferraz, N;
ACS APPLIED MATERIALS & INTERFACES
2023

Blood pH Analysis in Combination with Molecular Medical Tools in Relation to COVID-19 Symptoms
Siebert, HC; Eckert, T; Bhunia, A; Klatte, N; Mohri, M; Siebert, S; Kozarova, A; Hudson, JW; Zhang, RY; Zhang, N; Li, L; Gousias, K; Kanakis, D; Yan, MD; Jiménez-Barbero, J; Kozár, T; Nifantiev, ...
BIOMEDICINES
2023

Measuring (biological) materials mechanics with atomic force microscopy. 5. Traction force microscopy (cell traction forces)
Gil-Redondo, JC; Weber, A; Vivanco, MD; Toca-Herrera, JL;
MICROSCOPY RESEARCH AND TECHNIQUE
2023

Orally Administered Bifidobacterium adolescentis Diminishes Serum Glutamate Concentration in Mice
Royo, F; Tames, H; Bordanaba-Florit, G; Cabrera, D; Azparren-Angulo, M; Garcia-Vallicrosa, C; Margolles, A; Ruiz, L; Ruas-Madiedo, P; Falcon-Perez, JM;
MICROBIOLOGY SPECTRUM
2023

Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol-Gel Coating
Cerqueira, A; Romero-Gavilán, F; Helmholz, H; Azkargorta, M; Elortza, F; Gurruchaga, M; Goñi, I; Willumeit-Römer, R; Suay, J;
ACS BIOMATERIALS SCIENCE & ENGINEERING
2023

Genomic insights into metabolic flux in hummingbirds
Gershman, A; Hauck, Q; Dick, M; Jamison, JM; Tassia, M; Agirrezabala, X; Muhammad, S; Ali, R; Workman, RE; Valle, M; Wong, GW; Welch, KC; Timp, W;
GENOME RESEARCH
2023

CryoEM analysis of the essential native UDP-glucose pyrophosphorylase from Aspergillus nidulans reveals key conformations for activity regulation and function
Han, X; DAngelo, C; Otamendi, A; Cifuente, JO; de Astigarraga, E; Ochoa-Lizarralde, B; Grininger, M; Routier, FH; Guerin, ME; Fuehring, J; Etxebeste, O; Connell, SR;
MBIO
2023

Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
Lapitz, A; Azkargorta, M; Milkiewicz, P; Olaizola, P; Zhuravleva, E; Grimsrud, MM; Schramm, C; Arbelaiz, A; ORourke, CJ; La Casta, A; Milkiewicz, M; Pastor, T; Vesterhus, M; Jimenez-Agüero, ...
JOURNAL OF HEPATOLOGY
2023

Tuberous Sclerosis Complex cell-derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers
Ni Bhaoighill, M; Falcon-Perez, JM; Royo, F; Tee, AR; Webber, JP; Dunlop, EA;
Journal of Extracellular Vesicles
2023

Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
van Amerongen, R; Bentires-Alj, M; van Boxtel, AL; Clarke, RB; Fre, S; Suarez, EG; Iggo, R; Jechlinger, M; Jonkers, J; Mikkola, ML; Koledova, ZS; Sorlie, T; Vivanco, MD;
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
2023

Synthesis of a glycan hairpin
Fittolani, G; Tyrikos-Ergas, T; Poveda, A; Yu, Y; Yadav, N; Seeberger, PH; Jiménez-Barbero, J; Delbianco, M;
NATURE CHEMISTRY
2023

Magnesium and Liver Metabolism Through the Lifespan
Bravo, M; Simón, J; González-Recio, I; Martinez-Cruz, LA; Goikoetxea-Usandizaga, N; Martínez-Chantar, ML;
ADVANCES IN NUTRITION
2023

Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction
Lodge, S; Lawler, NG; Gray, N; Masuda, R; Nitschke, P; Whiley, L; Bong, SH; Yeap, BB; Dwivedi, G; Spraul, M; Schaefer, H; Gil-Redondo, R; Embade, N; Millet, O; Holmes, E; Wist, J; Nicholson, JK;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Serum and Urine Metabolomic Profiling of Newly Diagnosed Treatment-Naive Inflammatory Bowel Disease Patients
Aldars-García, L; Gil-Redondo, R; Embade, N; Riestra, S; Rivero, M; Gutiérrez, A; Rodríguez-Lago, I; Fernández-Salazar, L; Ceballos, D; Benitez, JM; Aguas, M; Baston-Rey, I; Bermejo, F; Casanova, ...
INFLAMMATORY BOWEL DISEASES
2023

The NCIWEB Server: A Novel Implementation of the Noncovalent Interactions Index for Biomolecular Systems
Novoa, T; Laplaza, R; Peccati, F; Fuster, F; Contreras-García, J;
JOURNAL OF CHEMICAL INFORMATION AND MODELING
2023

Characterization of Breast Cancer Aggressiveness by Cell Mechanics
Zbiral, B; Weber, A; Vivanco, MD; Toca-Herrera, JL;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver Diseases
Gil, M; Azkargorta, M; Fuster, C; Martínez-Gómez, M; Raurell, I; Barberá, A; Pericàs, JM; Hide, D; Elortza, F; Genescà, J; Martell, M;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Exogenous aralar/slc25a12 can replace citrin/slc25a13 as malate aspartate shuttle component in liver
González-Moreno, L; Santamaría-Cano, A; Paradela, A; Martínez-Chantar, ML; Martín, MA; Pérez-Carreras, M; García-Picazo, A; Vázquez, J; Calvo, E; González-Aseguinolaza, G; Saheki, T; del Arco, ...
MOLECULAR GENETICS AND METABOLISM REPORTS
2023

Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol-gel coating
García-Arnáez, I; Romero-Gavilán, F; Cerqueira, A; Azkargorta, M; Elortza, F; Suay, J; Goñi, I; Gurruchaga, M;
JOURNAL OF MATERIALS CHEMISTRY B
2023

Urinary Metabolomic Profile of Youth at Risk of Chronic Kidney Disease in Nicaragua
Hall, SM; Raines, NH; Ramirez-Rubio, O; Amador, JJ; López-Pilarte, D; OCallaghan-Gordo, C; Gil-Redondo, R; Embade, N; Millet, O; Peng, XJ; Vences, S; Keogh, SA; Delgado, IS; Friedman, DJ; Brooks, ...
KIDNEY360
2023

METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer
García-Vilchez, R; Anazco-Guenkova, AM; Dietmann, S; López, J; Morón-Calvente, V; DAmbrosi, S; Nombela, P; Zamacola, K; Mendizabal, I; García-Longarte, S; Zabala-Letona, A; Astobiza, I; Fernández, ...
MOLECULAR CANCER
2023

The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Goikoetxea-Usandizaga, N; Bravo, M; Egia-Mendikute, L; Abecia, L; Serrano-Maciá, M; Urdinguio, RG; Clos-García, M; Rodríguez-Agudo, R; Araujo-Legido, R; López-Bermudo, L; Delgado, TC; Lachiondo-Ortega, ...
HEPATOLOGY
2023

Potential use of heat shock protein 90 as a biomarker for the diagnosis of human diseases
Rivas-Macho, A; Romeo, MV; Rackles, E; Olabarria, G; Falcon-Perez, JM; Berganza-Granda, J; Cortajarena, AL; GoÃ±i-de-Cerio, F;
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
2023

N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
Garcia-Vilchez, R; Anazco-Guenkova, AM; López, J; Dietmann, S; Tomé, M; Jimeno, S; Azkargorta, M; Elortza, F; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Sánchez-Martín, MA; Huertas, P; Durán, ...
ONCOGENE
2023

Advances in Platelet Rich Plasma-Derived Extracellular Vesicles for Regenerative Medicine: A Systematic-Narrative Review
Anitua, E; Troya, M; Falcon-Pérez, JM; López-Sarrio, S; González, E; Alkhraisat, MH;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023

Synthetic Heparanase Inhibitors Can Prevent Herpes Simplex Viral Spread
Chopra, P; Yadavalli, T; Palmieri, F; Jongkees, SAK; Unione, L; Shukla, D; Boons, GJ;
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2023

Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function
Gonzalez-Rellan, MJ; Parracho, T; Heras, V; Rodriguez, A; Fondevila, MF; Novoa, E; Lima, N; Varela-Rey, M; Senra, A; Chantada-Vazquez, MDP; Ameneiro, C; Bernardo, G; Fernandez-Ramos, D; Lopitz-Otsoa, ...
MOLECULAR METABOLISM
2023

Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Capelo-Diz, A; Lachiondo-Ortega, S; Fernández-Ramos, D; Cañas-Martín, J; Goikoetxea-Usandizaga, N; Serrano-Maciá, M; González-Rellan, MJ; Mosca, L; Blazquez-Vicens, J; Tinahones-Ruano, A; Fondevila, ...
CELL METABOLISM
2023

Merging the Isonitrile-Tetrazine (4+1) Cycloaddition and the Ugi Four-Component Reaction into a Single Multicomponent Process
Méndez, Y; Vasco, AV; Ivey, G; Dias, AL; Gierth, P; Sousa, BB; Navo, CD; Torres-Mozas, A; Rodrigues, T; Jiménez-Osés, G; Bernardes, GJL;
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2023

The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
Foskolou, IP; Cunha, PP; Sanchez-Lopez, E; Minogue, EA; Nicolet, BP; Guislain, A; Jorgensen, C; Kostidis, S; Zandhuis, ND; Barbieri, L; Bargiela, D; Nathanael, D; Tyrakis, PA; Palazon, A; Giera, ...
CELL REPORTS
2023

Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis
Roberti, A; Tejedor, JR; Díaz-Moreno, I; López, V; Santamarina-Ojeda, P; Pérez, RF; Urdinguio, RG; Concellón, C; Martínez-Chantar, ML; Fernández-Morera, JL; Díaz-Quintana, A; del Amo, V; Fernández, ...
SCIENTIFIC REPORTS
2023

Mendelian randomisation shows diverticular disease and irritable bowel syndrome increase the risk of haemorrhoidal disease
Juzenas, S; Ellinghaus, D; Sanna, S; Franke, A; DAmato, M;
GUT
2023

The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis
Eichenberger, M; Schwander, T; Hüppi, S; Kreuzer, J; Mittl, PRE; Peccati, F; Jimenez-Osés, G; Naesby, M; Buller, RM;
Nature Catalysis
2023

Experimental and Theoretical Analysis of the Thiol-Promoted Fragmentation of 2-Halo-3-tosyl-oxanorbornadienes
Carranza, M; Carmona, AT; Navo, CD; Robina, I; Fratta, S; Newburn, C; Jiménez-Osés, G; Moreno-Vargas, AJ;
ORGANIC LETTERS
2023

Amyloid Fibrils Formed by Short Prion-Inspired Peptides Are Metalloenzymes
Navarro, S; Díaz-Caballero, M; Peccati, F; Roldán-Martín, L; Sodupe, M; Ventura, S;
ACS NANO
2023

Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
Garcia-Etxebarria, K; Etxart, A; Barrero, M; Nafria, B; Merino, NM; Romero-Garmendia, I; Goel, A; Franke, A; DAmato, M; Bujanda, L;
CANCERS
2023

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
Eraña, H; Díaz-Domínguez, CM; Charco, JM; Vidal, E; González-Miranda, E; Pérez-Castro, MA; Piñeiro, P; López-Moreno, R; Sampedro-Torres-Quevedo, C; Fernández-Veiga, L; Tasis-Galarza, J; Lorenzo, ...
ACTA NEUROPATHOLOGICA COMMUNICATIONS
2023

Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death
Sauve, F; Nampoothiri, S; Clarke, SA; Fernandois, D; Coêlho, CFF; Dewisme, J; Mills, EG; Ternier, G; Cotellessa, L; Iglesias-Garcia, C; Mueller-Fielitz, H; Lebouvier, T; Perbet, R; Florent, ...
EBIOMEDICINE
2023

Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis
Peña-Cearra, A; Castelo, J; Lavín, JL; Gonzalez-Lopez, M; Pascual-Itoiz, MA; Fuertes, M; de Juan, VG; Bárcena, L; Martín-Ruiz, I; Pellón, A; Seoane, I; Barriales, D; Palacios, A; Fullaondo, ...
GUT MICROBES
2023

Factor-inhibiting HIF (FIH) promotes lung cancer
García-del Río, AGD; Prieto-Fernández, E; Egia-Mendikute, L; Antonana-Vildosola, A; Jimenez-Lasheras, B; Lee, SY; Barreira-Manrique, A; Zanetti, SR; de Blas, A; Velasco-Beltrán, P; Bosch, A; ...
JCI INSIGHT
2023

Human Leukocyte Antigen Signatures as Pathophysiological Discriminants of Microscopic Colitis Subtypes
Zheng, TH; Roda, G; Zabana, Y; Escudero-Hernández, C; Liu, XR; Chen, Y; Tavares, LC; Bonfiglio, F; Mellander, MR; Janczewska, I; Vigren, L; Sjöberg, K; Ohlsson, B; Almer, S; Halfvarson, J; Miehlke, ...
JOURNAL OF CROHNS & COLITIS
2023