Publications

2021

Iminosugar C-Glycosides Work as Pharmacological Chaperones of NAGLU, a Glycosidase Involved in MPS IIIB Rare Disease**
Zhu, S;Jagadeesh, Y;Tran, AT;Imaeda, S;Boraston, A;Alonzi, DS;Poveda, A;Zhang, YM;Desire, J;Charollais-Thoenig, J;Demotz, S;Kato, A;Butters, TD;Jimenez-Barbero, J;Sollogoub, M;Bleriot, Y
CHEMISTRY-A EUROPEAN JOURNAL
2021

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes
Pellon, A;Barriales, D;Pena-Cearra, A;Castelo-Careaga, J;Palacios, A;Lopez, N;Atondo, E;Pascual-Itoiz, MA;Martin-Ruiz, I;Sampedro, L;Gonzalez-Lopez, M;Barcena, L;Martin-Mateos, T;Landete, JM;Prados-Rosales, ...
GUT MICROBES
2021

Cerebrospinal Fluid and Plasma Small Extracellular Vesicles and miRNAs as Biomarkers for Prion Diseases
Lopez-Perez, O;Sanz-Rubio, D;Hernaiz, A;Betancor, M;Otero, A;Castilla, J;Andreoletti, O;Badiola, JJ;Zaragoza, P;Bolea, R;Toivonen, JM;Martin-Burriel, I
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Esparza-Baquer, A;Labiano, I;Sharif, O;Agirre-Lizaso, A;Oakley, F;Rodrigues, PM;Zhuravleva, E;O'Rourke, CJ;Hijona, E;Jimenez-Aguero, R;Riano, I;Landa, A;La Casta, A;Zaki, MYW;Munoz-Garrido, ...
GUT
2021

Extracellular Vesicles in the Fungi Kingdom
Liebana-Jordan, M;Brotons, B;Falcon-Perez, JM;Gonzalez, E
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Characterizing ligand-induced conformational changes in clinically relevant galectin-1 by H-N/H2O (D2O) exchange
Schedlbauer, A;Gilles, U;Ludwig, AK;Adler, A;Kaltner, H;Lindner, I;Mayo, KH;Diercks, T;Reusch, D;Gabius, HJ
BIOCHIMIE
2021

Selective C-13-Labels on Repeating Glycan Oligomers to Reveal Protein Binding Epitopes through NMR: Polylactosamine Binding to Galectins
Moure, MJ;Gimeno, A;Delgado, S;Diercks, T;Boons, GJ;Jimenez-Barbero, J;Arda, A
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2021

Unambiguous Tracking of Protein Phosphorylation by Fast High-Resolution FOSY NMR**
Lesovoy, DM;Georgoulia, PS;Diercks, T;Matecko-Burmann, I;Burmann, BM;Bocharov, EV;Bermel, W;Orekhov, VY
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2021

Chemoenzymatic Synthesis of Complex N-Glycans of the Parasite S. mansoni to Examine the Importance of Epitope Presentation on DC-SIGN recognition
Srivastava, AD;Unione, L;Bunyatov, M;Gagarinov, IA;Delgado, S;Abrescia, NGA;Arda, A;Boons, GJ
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
2021

Diagnostic Potential of the Plasma Lipidome in Infectious Disease: Application to Acute SARS-CoV-2 Infection
Gray, N;Lawler, NG;Zeng, ANX;Ryan, M;Bong, SH;Boughton, BA;Bizkarguenaga, M;Bruzzone, C;Embade, N;Wist, J;Holmes, E;Millet, O;Nicholson, JK;Whiley, L
METABOLITES
2021

Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet
Stenlund, H;Nilholm, C;Chorell, E;Roth, B;D'Amato, M;Ohlsson, B
METABOLITES
2021

Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease
Zheng, TH;Ellinghaus, D;Juzenas, S;Cossais, F;Burmeister, G;Mayr, G;Jorgensen, IF;Teder-Laving, M;Skogholt, AH;Chen, SS;Strege, PR;Ito, G;Banasik, K;Becker, T;Bokelmann, F;Brunak, S;Buch, S;Clausnitzer, ...
GUT
2021

Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease
Lee-Law, PY;Olaizola, P;Caballero-Camino, FJ;Izquierdo-Sanchez, L;Rodrigues, PM;Perugorria, MJ;Azkargorta, M;Elortza, F;Martinez-Chantar, ML;Aspichueta, P;Marzioni, M;Bujanda, L;Drenth, JPH;Banales, ...
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
2021

Advances in chemical probing of protein O-GlcNAc glycosylation: structural role and molecular mechanisms
Saha, A;Bello, D;Fernandez-Tejada, A
CHEMICAL SOCIETY REVIEWS
2021

Atomistic insights into the structure of heptapeptide nanofibers
Peccati, F;Sodupe, M
JOURNAL OF CHEMICAL PHYSICS
2021

A molecular signature for the metabolic syndrome by urine metabolomics
Bruzzone, C;Gil-Redondo, R;Seco, M;Barragan, R;de la Cruz, L;Cannet, C;Schafer, H;Fang, F;Diercks, T;Bizkarguenaga, M;Gonzalez-Valle, B;Lain, A;Sanz-Parra, A;Coltell, O;de Letona, AL;Spraul, ...
CARDIOVASCULAR DIABETOLOGY
2021

Deregulated 14-3-3 zeta and methionine adenosyltransferase alpha 1 interplay promotes liver cancer tumorigenesis in mice and humans
Lu, LQ;Zhang, J;Fan, W;Li, Y;Wang, JH;Li, TWH;Torres, LB;Mato, JM;Liu, T;Seki, E;Matsuda, M;Tomasi, ML;Bhowmick, NA;Yang, HP;Lu, SC
ONCOGENE
2021

A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses
Garcia-Etxebarria, K;Carbone, F;Teder-Laving, M;Pandit, A;Holvoet, L;Thijs, V;Lemmens, R;Bujanda, L;Franke, A;Zollner, S;Boehnke, M;Zawistowski, M;Esko, T;Jan, T;D'Amato, M
NEUROGASTROENTEROLOGY AND MOTILITY
2021

Nucleophilic catalysis of p-substituted aniline derivatives in acylhydrazone formation and exchange
Canal-Martin, A;Navo, CD;Saez, E;Molero, D;Jimenez-Oses, G;Perez-Fernandez, R
ORGANIC & BIOMOLECULAR CHEMISTRY
2021

Oral vaccination stimulates neutrophil functionality and exerts protection in a Mycobacterium avium subsp. paratuberculosis infection model
Ladero-Aunon, I;Molina, E;Oyanguren, M;Barriales, D;Fuertes, M;Sevilla, IA;Luo, L;Arrazuria, R;De Buck, J;Anguita, J;Elguezabal, N
NPJ VACCINES
2021

Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii
Fernandez-Rodriguez, C;Oyenarte, I;Conter, C;Gonzalez-Recio, I;Nunez-Franco, R;Gil-Pitarch, C;Quintana, I;Jimenez-Oses, G;Dominici, P;Martinez-Chantar, ML;Astegno, A;Martinez-Cruz, LA
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
2021

Integrative Modeling of Plasma Metabolic and Lipoprotein Biomarkers of SARS-CoV-2 Infection in Spanish and Australian COVID-19 Patient Cohorts
Masuda, R;Lodge, S;Nitschke, P;Spraul, M;Schaefer, H;Bong, SH;Kimhofer, T;Hall, D;Loo, RL;Bizkarguenaga, M;Bruzzone, C;Gil-Redondo, R;Embade, N;Mato, JM;Holmes, E;Wist, J;Millet, O;Nicholson, JK
JOURNAL OF PROTEOME RESEARCH
2021

Probing an Ixodes ricinus salivary gland yeast surface display with tick-exposed human sera to identify novel candidates for an anti-tick vaccine
Trentelman, JJA;Tomas-Cortazar, J;Knorr, S;Barriales, D;Hajdusek, O;Sima, R;Ersoz, JI;Narasimhan, S;Fikrig, E;Nijhof, AM;Anguita, J;Hovius, JW
SCIENTIFIC REPORTS
2021

A Catalogus Immune Muris of the mouse immune responses to diverse pathogens
Barlier, C;Barriales, D;Samosyuk, A;Jung, S;Ravichandran, S;Medvedeva, YA;Anguita, J;del Sol, A
CELL DEATH & DISEASE
2021

Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells
Nolan, LM;Cain, AK;Clamens, T;Furniss, RCD;Manoli, E;Sainz-Polo, MA;Dougan, G;Albesa-Jove, D;Parkhill, J;Mavridou, DAI;Filloux, A
NATURE MICROBIOLOGY
2021

O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Gonzalez-Rellan, MJ;Fondevila, MF;Fernandez, U;Rodriguez, A;Varela-Rey, M;Veyrat-Durebex, C;Seoane, S;Bernardo, G;Lopitz-Otsoa, F;Fernandez-Ramos, D;Bilbao, J;Iglesias, C;Novoa, E;Ameneiro, ...
NATURE COMMUNICATIONS
2021

Arylethynyltrifluoroborate Dienophiles for on Demand Activation of IEDDA Reactions
Zawada, Z;Guo, ZJ;Oliveira, BL;Navo, CD;Li, H;Cal, PMSD;Corzana, F;Jimenez-Oses, G;Bernardes, GJL
BIOCONJUGATE CHEMISTRY
2021

Protein adsorption/desorption dynamics on Ca-enriched titanium surfaces: biological implications
Romero-Gavilan, F;Cerqueira, A;Anitua, E;Tejero, R;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Izquierdo, R;Azkargorta, M;Elortza, F;Gurruchaga, M;Goni, I;Suay, J
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
2021

Association of Polygenic Risk Score and Bacterial Toxins at Screening Colonoscopy with Colorectal Cancer Progression: A Multicenter Case-Control Study
Piciocchi, A;Germinario, EAP;Etxebarria, KG;Rossi, S;Sanchez-Mete, L;Porowska, B;Stigliano, V;Trentino, P;Oddi, A;Accarpio, F;Grazi, GL;Bruno, G;Bonucci, M;Giambenedetti, M;Spigaglia, P;Barbanti, ...
TOXINS
2021

GH18 endo-beta-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
Trastoy, B;Du, JJ;Li, C;Garcia-Alija, M;Klontz, EH;Roberts, BR;Donahue, TC;Wang, LX;Sundberg, EJ;Guerin, ME
JOURNAL OF BIOLOGICAL CHEMISTRY
2021

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Vosa, U;Claringbould, A;Westra, HJ;Bonder, MJ;Deelen, P;Zeng, B;Kirsten, H;Saha, A;Kreuzhuber, R;Yazar, S;Brugge, H;Oelen, R;de Vries, DH;van der Wijst, MGP;Kasela, S;Pervjakova, N;Alves, I;Fave, ...
NATURE GENETICS
2021

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart
Barriales, D;Martin-Ruiz, I;Carreras-Gonzalez, A;Montesinos-Robledo, M;Azkargorta, M;Iloro, I;Escobes, I;Martin-Mateos, T;Atondo, E;Palacios, A;Gonzalez-Lopez, M;Barcena, L;Cortazar, AR;Cabrera, ...
PLOS BIOLOGY
2021

Identification of Isomeric N-Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry
Torano, JS;Aizpurua-Olaizola, O;Wei, N;Li, TH;Unione, L;Jimenez-Oses, G;Corzana, F;Somovilla, VJ;Falcon-Perez, JM;Boons, GJ
CHEMISTRY-A EUROPEAN JOURNAL
2021

The Importance of Computational Modeling in Stem Cell Research
del Sol, A;Jung, S
TRENDS IN BIOTECHNOLOGY
2021

Extracellular vesicles in hepatology: Physiological role,involvement in pathogenesis, and therapeutic opportunities
Azparren-Angulo, M;Royo, F;Gonzalez, E;Liebana, M;Brotons, B;Berganza, J;Goni-de-Cerio, F;Manicardi, N;Abad-Jorda, L;Gracia-Sancho, J;Falcon-Perez, JM
PHARMACOLOGY & THERAPEUTICS
2021

Preclinical Inflammatory Bowel Disease: Back to the Future
Rodriguez-Lago, I;Marigorta, UM;Barreiro-de Acosta, M
GASTROENTEROLOGY
2021

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease
Otero, A;Betancor, M;Erana, H;Borges, NF;Lucas, JJ;Badiola, JJ;Castilla, J;Bolea, R
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Computational Stem Cell Biology: Open Questions and Guiding Principles
Cahan, P;Cacchiarelli, D;Dunn, SJ;Hemberg, M;Lopes, SMCD;Morris, SA;Rackham, OJ;del Sol, A;Wells, CA
CELL STEM CELL
2021

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action
Pifferi, C;Fuentes, R;Fernandez-Tejada, A
NATURE REVIEWS CHEMISTRY
2021

Heparin length in the coating of extremely small iron oxide nanoparticles regulates in vivo theranostic applications
Groult, H;Carregal-Romero, S;Castejon, D;Azkargorta, M;Miguel-Coello, AB;Pulagam, KR;Gomez-Vallejo, V;Cousin, R;Munoz-Caffarel, M;Lawrie, CH;Llop, J;Piot, JM;Elortza, F;Maugard, T;Ruiz-Cabello, ...
NANOSCALE
2021

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules
Royo, F;Azkargorta, M;Lavin, JL;Clos-Garcia, M;Cortazar, AR;Gonzalez-Lopez, M;Barcena, L;del Portillo, HA;Yanez-Mo, M;Marcilla, A;Borras, FE;Peinado, H;Guerrero, I;Vales-Gomez, M;Cereijo, U;Sardon, ...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021

Replacing the Rhamnose-Xylose Moiety of QS-21 with Simpler Terminal Disaccharide Units Attenuates Adjuvant Activity in Truncated Saponin Variants
Fuentes, R;Ruiz-de-Angulo, A;Sacristan, N;Navo, CD;Jimenez-Oses, G;Anguita, J;Fernandez-Tejada, A
CHEMISTRY-A EUROPEAN JOURNAL
2021

Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold
Basler, S;Studer, S;Zou, YK;Mori, T;Ota, Y;Camus, A;Bunzel, HA;Helgeson, RC;Houk, KN;Jimenez-Oses, G;Hilvert, D
NATURE CHEMISTRY
2021

Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets
Spethmann, T;Bockelmann, LC;Labitzky, V;Ahlers, AK;Schroder-Schwarz, J;Bonk, S;Simon, R;Sauter, G;Huland, H;Kypta, R;Schumacher, U;Lange, T
MOLECULAR ONCOLOGY
2021

Leveraging systems biology for predicting modulators of inflammation in patients with COVID-19
Jung, S;Potapov, I;Chillara, S;del Sol, A
SCIENCE ADVANCES
2021

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia
Nguyen, TL;Nokin, MJ;Teres, S;Tome, M;Bodineau, C;Galmar, O;Pasquet, JM;Rousseau, B;van Liempd, S;Falcon-Perez, JM;Richard, E;Muzotte, E;Rezvani, HR;Priault, M;Bouchecareilh, M;Redonnet-Vernhet, ...
MOLECULAR ONCOLOGY
2021

3D Cell Cultures as Prospective Models to Study Extracellular Vesicles in Cancer
Bordanaba-Florit, G;Madarieta, I;Olalde, B;Falcon-Perez, JM;Royo, F
CANCERS
2021

Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Lee-Law, PY;Olaizola, P;Caballero-Camino, FJ;Izquierdo-Sanchez, L;Rodrigues, PM;Santos-Laso, A;Azkargorta, M;Elortza, F;Martinez-Chantar, ML;Perugorria, MJ;Aspichueta, P;Marzioni, M;LaRusso, ...
JOURNAL OF HEPATOLOGY
2021

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points
Fondevila, MF;Mercado-Gomez, M;Rodriguez, A;Gonzalez-Rellan, MJ;Iruzubieta, P;Valenti, V;Escalada, J;Schwaninger, M;Prevot, V;Dieguez, C;Crespo, J;Fruhbeck, G;Martinez-Chantar, ML;Nogueiras, R
JOURNAL OF HEPATOLOGY
2021

pH-Responsive Self-Assembly of Amyloid Fibrils for Dual Hydrolase-Oxidase Reactions
Diaz-Caballero, M;Navarro, S;Nuez-Martinez, M;Peccati, F;Rodriguez-Santiago, L;Sodupe, M;Teixidor, F;Ventura, S
ACS CATALYSIS
2021

Therapeutic Targeting of Fumaryl Acetoacetate Hydrolase in Hereditary Tyrosinemia Type I
Gil-Martinez, J;Macias, I;Unione, L;Bernardo-Seisdedos, G;Lopitz-Otsoa, F;Fernandez-Ramos, D;Lain, A;Sanz-Parra, A;Mato, JM;Millet, O
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities
Simon, J;Delgado, TC;Martinez-Cruz, LA;Martinez-Chantar, ML
BIOMEDICINES
2021

Glutamine, fatty liver disease and aging
Simon, J;Martinez-Chantar, ML;Delgado, TC
AGING-US
2021

Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Iloro, I;Azkargorta, M;Elortza, F;Izquierdo, R;Gurruchaga, M;Goni, I;Suay, J
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
2021

The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2)
Franken, GAC;Muller, D;Mignot, C;Keren, B;Levy, J;Tabet, AC;Germanaud, D;Tejada, MI;Kroes, HY;Nievelstein, RAJ;Brimble, E;Ruzhnikov, M;Claverie-Martin, F;Szczepanska, M;Cuk, M;Latta, F;Konrad, ...
HUMAN MUTATION
2021

Revisiting the Role of Natural Killer Cells in Non-Alcoholic Fatty Liver Disease
Martinez-Chantar, ML;Delgado, TC;Beraza, N
FRONTIERS IN IMMUNOLOGY
2021

A computer-guided design tool to increase the efficiency of cellular conversions
Jung, S;Appleton, E;Ali, M;Church, GM;del Sol, A
NATURE COMMUNICATIONS
2021

Toward Enantiomerically Pure beta-Seleno-alpha-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Oroz, P;Navo, CD;Avenoza, A;Busto, JH;Corzana, F;Jimenez-Oses, G;Peregrina, JM
ORGANIC LETTERS
2021

The Phosphatidyl-myo-Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo
Boldrin, F;Anso, I;Alebouyeh, S;Sevilla, IA;Geijo, M;Garrido, JM;Marina, A;Mazzabo, LC;Segafreddo, G;Guerin, ME;Manganelli, R;Prados-Rosales, R
JOURNAL OF BACTERIOLOGY
2021

Adipocyte-derived extracellular vesicles regulate survival and function of pancreatic beta cells
Gesmundo, I;Pardini, B;Gargantini, E;Gamba, G;Birolo, G;Fanciulli, A;Banfi, D;Congiusta, N;Favaro, E;Deregibus, MC;Togliatto, G;Zocaro, G;Brizzi, MF;Luque, RM;Castano, JP;Bocchiotti, MA;Arolfo, ...
JCI INSIGHT
2021

In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation
Revuelta, M;Elicegui, A;Scheuer, T;Endesfelder, S;Buhrer, C;Moreno-Cugnon, L;Matheu, A;Schmitz, T
AGING-US
2021

Synthesis and chelation study of a fluoroionophore and a glycopeptide based on an aza crown iminosugar structure
Bordes, A;Poveda, A;Fontelle, N;Arda, A;Guillard, J;Bin Ruan, Y;Marrot, J;Imaeda, S;Kato, A;Desire, J;Xie, J;Jimenez-Barbero, J;Bleriot, Y
CARBOHYDRATE RESEARCH
2021

Bovine Neutrophils Release Extracellular Traps and Cooperate With Macrophages in Mycobacterium avium subsp. paratuberculosis clearance In Vitro
Ladero-Aunon, I;Molina, E;Holder, A;Kolakowski, J;Harris, H;Urkitza, A;Anguita, J;Werling, D;Elguezabal, N
FRONTIERS IN IMMUNOLOGY
2021

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton
Bozal-Basterra, L;Gonzalez-Santamarta, M;Muratore, V;Martin-Martin, N;Ercilla, A;Rodriguez, JA;Carracedo, A;Sutherland, JD;Barrio, R
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021

Extracellular vesicles in the context of Mycobacterium tuberculosis infection
Palacios, A;Gupta, S;Rodriguez, GM;Prados-Rosales, R
MOLECULAR IMMUNOLOGY
2021

The two domains of human galectin-8 bind sialyl- and fucose-containing oligosaccharides in an independent manner. A 3D view by using NMR
Gomez-Redondo, M;Delgado, S;Nunez-Franco, R;Jimenez-Oses, G;Arda, A;Jimenez-Barbero, J;Gimeno, A
RSC CHEMICAL BIOLOGY
2021

Dynamic Intracellular Metabolic Cell Signaling Profiles During Ag-Dependent B-Cell Differentiation
Diez, P;Perez-Andres, M;Bogsted, M;Azkargorta, M;Garcia-Valiente, R;Degano, RM;Blanco, E;Mateos-Gomez, S;Barcena, P;Santa Cruz, S;Gongora, R;Elortza, F;Landeira-Vinuela, A;Juanes-Velasco, P;Segura, ...
FRONTIERS IN IMMUNOLOGY
2021

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations
Quintana, JI;Delgado, S;Nunez-Franco, R;Canada, FJ;Jimenez-Oses, G;Jimenez-Barbero, J;Arda, A
FRONTIERS IN CHEMISTRY
2021

Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures
Campanero-Rhodes, MA;Kalograiaki, I;Euba, B;Llobet, E;Arda, A;Jimenez-Barbero, J;Garmendia, J;Solis, D
BIOMOLECULES
2021

Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration
Anitua, E;Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Azkargorta, M;Elortza, F;Gurruchaga, M;Goni, I;Suay, J;Tejero, R
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
2021

Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals
Egia-Mendikute, L;Bosch, A;Prieto-Fernandez, E;Lee, SY;Jimenez-Lasheras, B;del Rio, AG;Antonana-Vildosola, A;Bruzzone, C;Bizkarguenaga, M;Embade, N;Gil-Redondo, R;Martinez-Chantar, ML;Lopez-Hoyos, ...
COMMUNICATIONS BIOLOGY
2021

The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase
Olazabal-Herrero, A;Bilbao-Arribas, M;Carlevaris, O;Sendino, M;Varela-Martinez, E;Jugo, BM;Berra, E;Rodriguez, JA
FEBS JOURNAL
2021

Evolution of DNA methylation in the human brain
Jeong, H;Mendizabal, I;Berto, S;Chatterjee, P;Layman, T;Usui, N;Toriumi, K;Douglas, C;Singh, D;Huh, I;Preuss, TM;Konopka, G;Yi, SV
NATURE COMMUNICATIONS
2021

Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins
Lima, CDL;Coelho, H;Gimeno, A;Trovao, F;Diniz, A;Dias, JS;Jimenez-Barbero, J;Corzana, F;Carvalho, AL;Cabrita, EJ;Marcelo, F
CHEMISTRY-A EUROPEAN JOURNAL
2021

Enzymatic Synthesis of Phloretin alpha-Glucosides Using a Sucrose Phosphorylase Mutant and its Effect on Solubility, Antioxidant Properties and Skin Absorption
Gonzalez-Alfonso, JL;Ubiparip, Z;Jimenez-Ortega, E;Poveda, A;Alonso, C;Coderch, L;Jimenez-Barbero, J;Sanz-Aparicio, J;Ballesteros, AO;Desmet, T;Plou, FJ
ADVANCED SYNTHESIS & CATALYSIS
2021

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation
Schijns, V;Majhen, D;van der Ley, P;Thakur, A;Summerfield, A;Berisio, R;Nativi, C;Fernandez-Tejada, A;Alvarez-Dominguez, C;Gizurarson, S;Zamyatina, A;Molinaro, A;Rosano, C;Jakopin, Z;Gursel, ...
PHARMACEUTICS
2021

FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state
Arruabarrena-Aristorena, A;Toska, E
MOLECULAR & CELLULAR ONCOLOGY
2021

Computational modelling of stem cell-niche interactions facilitates discovery of strategies to enhance tissue regeneration and counteract ageing
Potapov, I;Garcia-Prat, L;Ravichandran, S;Munoz-Canoves, P;del Sol, A
FEBS JOURNAL
2021

Biotin-phenosafranin as a new photosensitive conjugate for targeted therapy and imaging
Blauz, A;Rychlik, B;Plazuk, D;Peccati, F;Jimenez-Oses, G;Steinke, U;Sierant, M;Trzeciak, K;Skorupska, E;Miksa, B
NEW JOURNAL OF CHEMISTRY
2021

Origin and Control of Chemoselectivity in Cytochrome c Catalyzed Carbene Transfer into Si-H and N-H bonds
Garcia-Borras, M;Kan, SBJ;Lewis, RD;Tang, A;Jimenez-Oses, G;Arnold, FH;Houk, KN
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2021

Selective modulation by PARP-1 of HIF-1 alpha-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions
Marti, JM;Garcia-Diaz, A;Delgado-Bellido, D;O'Valle, F;Gonzalez-Flores, A;Carlevaris, O;Rodriguez-Vargas, JM;Ame, JC;Dantzer, F;King, GL;Dziedzic, K;Berra, E;de Alava, E;Amaral, AT;Hammond, ...
REDOX BIOLOGY
2021

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear
Ferreira, NC;Charco, JM;Plagenz, J;Orru, CD;Denkers, ND;Metrick, MA;Hughson, AG;Griffin, KA;Race, B;Hoover, EA;Castilla, J;Nichols, TA;Miller, MW;Caughey, B
SCIENTIFIC REPORTS
2021

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Erdbrugger, U;Blijdorp, CJ;Bijnsdorp, IV;Borras, FE;Burger, D;Bussolati, B;Byrd, JB;Clayton, A;Dear, JW;Falcon-Perez, JM;Grange, C;Hill, AF;Holthofer, H;Hoorn, EJ;Jenster, G;Jimenez, CR;Junker, ...
JOURNAL OF EXTRACELLULAR VESICLES
2021

Cosolute modulation of protein oligomerization reactions in the homeostatic timescale
Mateos, B;Bernardo-Seisdedos, G;Dietrich, V;Zalba, N;Ortega, G;Peccati, F;Jimenez-Oses, G;Konrat, R;Tollinger, M;Millet, O
BIOPHYSICAL JOURNAL
2021

Trimethylamine N-oxide is a new plant molecule that promotes abiotic stress tolerance
Catala, R;Lopez-Cobollo, R;Berbis, MA;Jimenez-Barbero, J;Salinas, J
SCIENCE ADVANCES
2021

Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Izquierdo, R;Azkargorta, M;Elortza, F;Gurruchaga, M;Suay, J;Goni, I
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
2021

Enthalpy-Entropy Compensation in Biomolecular Recognition: A Computational Perspective
Peccati, F;Jimenez-Oses, G
ACS OMEGA
2021

Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
Prieto-Fernandez, E;Egia-Mendikute, L;Vila-Vecilla, L;Bosch, A;Barreira-Manrique, A;Lee, SY;Garcia-del Rio, A;Antonana-Vildosola, A;Jimenez-Lasheras, B;Moreno-Cugnon, L;Jimenez-Barbero, J;Berra, ...
EMERGING MICROBES & INFECTIONS
2021

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs
Zolotarov, Y;Ma, C;Gonzalez-Recio, I;Hardy, S;Franken, GAC;Uetani, N;Latta, F;Kostantin, E;Boulais, J;Thibault, MP;Cote, JF;Moreno, ID;Quintana, AD;Hoenderop, JGJ;Martinez-Cruz, LA;Tremblay, ...
CELLULAR AND MOLECULAR LIFE SCIENCES
2021

Could protein content of Urinary Extracellular Vesicles be useful to detect Cirrhosis in Alcoholic Liver Disease?
Gonzalez, E;Azkargorta, M;Garcia-Vallicrosa, C;Prieto-Elordui, J;Elortza, F;Blanco-Sampascual, S;Falcon-Perez, JM
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2021

Impact of Cu(ii) and Al(iii) on the conformational landscape of amyloid beta(1-42)
Roldan-Martin, L;Peccati, F;Sciortino, G;Sodupe, M;Marechal, JD
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
2021

Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
Iruzubieta, P;Goikoetxea-Usandizaga, N;Barbier-Torres, L;Serrano-Macia, M;Fernandez-Ramos, D;Fernandez-Tussy, P;Gutierrez-de-Juan, V;Lachiondo-Ortega, S;Simon, J;Bravo, M;Lopitz-Otsoa, F;Robles, ...
JHEP REPORTS
2021

Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis
Bhattacharya, D;Basta, B;Mato, JM;Craig, A;Fernandez-Ramos, D;Lopitz-Otsoa, F;Tsvirkun, D;Hayardeny, L;Chandar, V;Schwartz, RE;Villanueva, A;Friedman, SL
JHEP REPORTS
2021

A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit
Schedlbauer, A;Iturrioz, I;Ochoa-Lizarralde, B;Diercks, T;Lopez-Alonso, JP;Lavin, JL;Kaminishi, T;Capuni, R;Dhimole, N;de Astigarraga, E;Gil-Carton, D;Fucini, P;Connell, SR
SCIENCE ADVANCES
2021

Transcriptomic Profiling of the Liver Sinusoidal Endothelium during Cirrhosis Reveals Stage-Specific Secretory Signature
Manicardi, N;Fernandez-Iglesias, A;Abad-Jorda, L;Royo, F;Azkargorta, M;Ortega-Ribera, M;Sanfeliu-Redondo, D;Martinez-Alcocer, A;Elortza, F;Hessheimer, AJ;Fondevila, C;Lozano, JJ;Garcia-Pagan, ...
CANCERS
2021

Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers
Bertuzzi, S;Gimeno, A;Martinez-Castillo, A;Lete, MG;Delgado, S;Airoldi, C;Tavares, MR;Blahova, M;Chytil, P;Kren, V;Abrescia, NGA;Arda, A;Bojarova, P;Jimenez-Barbero, J
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Preventing Memory Effects in Surface-Enhanced Raman Scattering Substrates by Polymer Coating and Laser-Activated Deprotection
Plou, J;Charconnet, M;Garcia, I;Calvo, J;Liz-Marzan, LM
ACS NANO
2021

Estrogen Modulates Epithelial Breast Cancer Cell Mechanics and Cell-to-Cell Contacts
Zbiral, B;Weber, A;Iturri, J;Vivanco, MDM;Toca-Herrera, JL
MATERIALS
2021

Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions
Franconetti, A;Arda, A;Asensio, JL;Bleriot, Y;Thibaudeau, S;Jimenez-Barbero, J
ACCOUNTS OF CHEMICAL RESEARCH
2021

E2F1 and E2F2-Mediated Repression of CPT2 Establishes a Lipid-Rich Tumor-Promoting Environment
Gonzalez-Romero, F;Mestre, D;Aurrekoetxea, I;O'Rourke, CJ;Andersen, JB;Woodhoo, A;Tamayo-Caro, M;Varela-Rey, M;Palomo-Irigoyen, M;Gomez-Santos, B;de Urturi, DS;Nunez-Garcia, M;Garcia-Rodriguez, ...
CANCER RESEARCH
2021

Metabolic Landscape of the Mouse Liver by Quantitative P-31 Nuclear Magnetic Resonance Analysis of the Phosphorome
Bernardo-Seisdedos, G;Bilbao, J;Fernandez-Ramos, D;Lopitz-Otsoa, F;de Juan, VG;Bizkarguenaga, M;Mateos, B;Fondevila, MF;Abril-Fornaguera, J;Diercks, T;Lu, SC;Nogueiras, R;Mato, JM;Millet, O
HEPATOLOGY
2021

An Fc-free EGFR-specific 4-1BB-agonistic Trimerbody Displays Broad Antitumor Activity in Humanized Murine Cancer Models without Toxicity
Compte, M;Harwood, SL;Erce-Llamazares, A;Tapia-Galisteo, A;Romero, E;Ferrer, I;Garrido-Martin, EM;Enguita, AB;Ochoa, MC;Blanco, B;Oteo, M;Merino, N;Nehme-Alvarez, D;Hangiu, O;Dominguez-Alonso, ...
CLINICAL CANCER RESEARCH
2021

Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
Fernandez-Tussy, P;Rodriguez-Agudo, R;Fernandez-Ramos, D;Barbier-Torres, L;Zubiete-Franco, I;de Davalillo, SL;Herraez, E;Goikoetxea-Usandizaga, N;Lachiondo-Ortega, S;Simon, J;Lopitz-Otsoa, F;Gutierrez-de ...
CELL DEATH & DISEASE
2021

Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Guillermo, BF;Royo, F;Kruglik, SG;Falcon-Perez, JM
NATURE PROTOCOLS
2021

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion
Goncalves, CA;Larsen, M;Jung, SC;Stratmann, J;Nakamura, A;Leuschner, M;Hersemann, L;Keshara, R;Perlman, S;Lundvall, L;Thuesen, LL;Hare, KJ;Amit, I;Jorgensen, A;Kim, YH;del Sol, A;Grapin-Botton, A
NATURE COMMUNICATIONS
2021

Identification of novel UROS mutations in a patient with congenital erythropoietic porphyria and efficient treatment by phlebotomy
Blouin, JM;Ged, C;Bernardo-Seisdedos, G;Cabantous, T;Pinson, B;Poli, A;Puy, H;Millet, O;Gouya, L;Morice-Picard, F;Richard, E
MOLECULAR GENETICS AND METABOLISM REPORTS
2021

3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme
Lazaro, M;Melero, R;Huet, C;Lopez-Alonso, JP;Delgado, S;Dodu, A;Bruch, EM;Abriata, LA;Alzari, PM;Valle, M;Lisa, MN
COMMUNICATIONS BIOLOGY
2021

Altered sphingolipid function in Alzheimer's disease; a gene regulatory network approach
Giovagnoni, C;Ali, M;Eijssen, LMT;Maes, R;Choe, K;Mulder, M;Kleinjans, J;del Sol, A;Glaab, E;Mastroeni, D;Delvaux, E;Coleman, P;Losen, M;Pishva, E;Martinez-Martinez, P;van den Hove, DLA
NEUROBIOLOGY OF AGING
2021

Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Colyn, L;Barcena-Varela, M;Alvarez-Sola, G;Latasa, MU;Uriarte, I;Santamaria, E;Herranz, JM;Santos-Laso, A;Arechederra, M;de Gauna, MR;Aspichueta, P;Canale, M;Casadei-Gardini, A;Francesconi, ...
HEPATOLOGY
2021

On-cell saturation transfer difference NMR for the identification of FimH ligands and inhibitors
Palmioli, A;Sperandeo, P;Bertuzzi, S;Polissi, A;Airoldi, C
BIOORGANIC CHEMISTRY
2021

Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development
Font-Diaz, J;Jimenez-Panizo, A;Caelles, C;Vivanco, MD;Perez, P;Aranda, A;Estebanez-Perpina, E;Castrillo, A;Ricote, M;Valledor, AF
SEMINARS IN CANCER BIOLOGY
2021

Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Simon, J;Goikoetxea-Usandizaga, N;Serrano-Macia, M;Fernandez-Ramos, D;de Urturi, DS;Gruskos, JJ;Fernandez-Tussy, P;Lachiondo-Ortega, S;Gonzalez-Recio, I;Rodriguez-Agudo, R;Gutierrez-de-Juan, ...
JOURNAL OF HEPATOLOGY
2021

Identification and Characterization of Immunodominant Proteins from Tick Tissue Extracts Inducing a Protective Immune Response against Ixodes ricinus in Cattle
Knorr, S;Reissert-Oppermann, S;Tomas-Cortazar, J;Barriales, D;Azkargorta, M;Iloro, I;Elortza, F;Pinecki-Socias, S;Anguita, J;Hovius, JW;Nijhof, AM
VACCINES
2021

NMR of glycoproteins: profiling, structure, conformation and interactions
Unione, L;Arda, A;Jimenez-Barbero, J;Millet, O
CURRENT OPINION IN STRUCTURAL BIOLOGY
2021

Sporadic Creutzfeldt-Jakob disease with extremely long 14-year survival period
Kortazar-Zubizarreta, I;Ruiz-Onandi, R;Pereda, A;Vado, Y;Gonzalez-Chinchon, G;Erana, H;de Nanclares, GP;Castilla, J
EUROPEAN JOURNAL OF NEUROLOGY
2021

Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria
Bernardo-Seisdedos, G;Charco, JM;SanJuan, I;Garcia-Martinez, S;Urquiza, P;Erana, H;Castilla, J;Millet, O
JOURNAL OF PERSONALIZED MEDICINE
2021

Microscopic colitis
Burke, KE;D'Amato, M;Ng, SC;Pardi, DS;Ludvigsson, JF;Khalili, H
NATURE REVIEWS DISEASE PRIMERS
2021