Publications

2021

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart
Barriales, D;Martin-Ruiz, I;Carreras-Gonzalez, A;Montesinos-Robledo, M;Azkargorta, M;Iloro, I;Escobes, I;Martin-Mateos, T;Atondo, E;Palacios, A;Gonzalez-Lopez, M;Barcena, L;Cortazar, AR;Cabrera, ...
PLOS BIOLOGY
2021

Identification of Isomeric N-Glycans by Conformer Distribution Fingerprinting using Ion Mobility Mass Spectrometry
Torano, JS;Aizpurua-Olaizola, O;Wei, N;Li, TH;Unione, L;Jimenez-Oses, G;Corzana, F;Somovilla, VJ;Falcon-Perez, JM;Boons, GJ
CHEMISTRY-A EUROPEAN JOURNAL
2021

The Importance of Computational Modeling in Stem Cell Research
del Sol, A;Jung, S
TRENDS IN BIOTECHNOLOGY
2021

Extracellular vesicles in hepatology: Physiological role,involvement in pathogenesis, and therapeutic opportunities
Azparren-Angulo, M;Royo, F;Gonzalez, E;Liebana, M;Brotons, B;Berganza, J;Goni-de-Cerio, F;Manicardi, N;Abad-Jorda, L;Gracia-Sancho, J;Falcon-Perez, JM
PHARMACOLOGY & THERAPEUTICS
2021

Preclinical Inflammatory Bowel Disease: Back to the Future
Rodriguez-Lago, I;Marigorta, UM;Barreiro-de Acosta, M
GASTROENTEROLOGY
2021

Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease
Otero, A;Betancor, M;Erana, H;Borges, NF;Lucas, JJ;Badiola, JJ;Castilla, J;Bolea, R
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Computational Stem Cell Biology: Open Questions and Guiding Principles
Cahan, P;Cacchiarelli, D;Dunn, SJ;Hemberg, M;Lopes, SMCD;Morris, SA;Rackham, OJ;del Sol, A;Wells, CA
CELL STEM CELL
2021

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action
Pifferi, C;Fuentes, R;Fernandez-Tejada, A
NATURE REVIEWS CHEMISTRY
2021

Heparin length in the coating of extremely small iron oxide nanoparticles regulates in vivo theranostic applications
Groult, H;Carregal-Romero, S;Castejon, D;Azkargorta, M;Miguel-Coello, AB;Pulagam, KR;Gomez-Vallejo, V;Cousin, R;Munoz-Caffarel, M;Lawrie, CH;Llop, J;Piot, JM;Elortza, F;Maugard, T;Ruiz-Cabello, ...
NANOSCALE
2021

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules
Royo, F;Azkargorta, M;Lavin, JL;Clos-Garcia, M;Cortazar, AR;Gonzalez-Lopez, M;Barcena, L;del Portillo, HA;Yanez-Mo, M;Marcilla, A;Borras, FE;Peinado, H;Guerrero, I;Vales-Gomez, M;Cereijo, U;Sardon, ...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021

Replacing the Rhamnose-Xylose Moiety of QS-21 with Simpler Terminal Disaccharide Units Attenuates Adjuvant Activity in Truncated Saponin Variants
Fuentes, R;Ruiz-de-Angulo, A;Sacristan, N;Navo, CD;Jimenez-Oses, G;Anguita, J;Fernandez-Tejada, A
CHEMISTRY-A EUROPEAN JOURNAL
2021

Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold
Basler, S;Studer, S;Zou, YK;Mori, T;Ota, Y;Camus, A;Bunzel, HA;Helgeson, RC;Houk, KN;Jimenez-Oses, G;Hilvert, D
NATURE CHEMISTRY
2021

Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets
Spethmann, T;Bockelmann, LC;Labitzky, V;Ahlers, AK;Schroder-Schwarz, J;Bonk, S;Simon, R;Sauter, G;Huland, H;Kypta, R;Schumacher, U;Lange, T
MOLECULAR ONCOLOGY
2021

Leveraging systems biology for predicting modulators of inflammation in patients with COVID-19
Jung, S;Potapov, I;Chillara, S;del Sol, A
SCIENCE ADVANCES
2021

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia
Nguyen, TL;Nokin, MJ;Teres, S;Tome, M;Bodineau, C;Galmar, O;Pasquet, JM;Rousseau, B;van Liempd, S;Falcon-Perez, JM;Richard, E;Muzotte, E;Rezvani, HR;Priault, M;Bouchecareilh, M;Redonnet-Vernhet, ...
MOLECULAR ONCOLOGY
2021

3D Cell Cultures as Prospective Models to Study Extracellular Vesicles in Cancer
Bordanaba-Florit, G;Madarieta, I;Olalde, B;Falcon-Perez, JM;Royo, F
CANCERS
2021

Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models
Lee-Law, PY;Olaizola, P;Caballero-Camino, FJ;Izquierdo-Sanchez, L;Rodrigues, PM;Santos-Laso, A;Azkargorta, M;Elortza, F;Martinez-Chantar, ML;Perugorria, MJ;Aspichueta, P;Marzioni, M;LaRusso, ...
JOURNAL OF HEPATOLOGY
2021

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points
Fondevila, MF;Mercado-Gomez, M;Rodriguez, A;Gonzalez-Rellan, MJ;Iruzubieta, P;Valenti, V;Escalada, J;Schwaninger, M;Prevot, V;Dieguez, C;Crespo, J;Fruhbeck, G;Martinez-Chantar, ML;Nogueiras, R
JOURNAL OF HEPATOLOGY
2021

pH-Responsive Self-Assembly of Amyloid Fibrils for Dual Hydrolase-Oxidase Reactions
Diaz-Caballero, M;Navarro, S;Nuez-Martinez, M;Peccati, F;Rodriguez-Santiago, L;Sodupe, M;Teixidor, F;Ventura, S
ACS CATALYSIS
2021

Therapeutic Targeting of Fumaryl Acetoacetate Hydrolase in Hereditary Tyrosinemia Type I
Gil-Martinez, J;Macias, I;Unione, L;Bernardo-Seisdedos, G;Lopitz-Otsoa, F;Fernandez-Ramos, D;Lain, A;Sanz-Parra, A;Mato, JM;Millet, O
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021

Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities
Simon, J;Delgado, TC;Martinez-Cruz, LA;Martinez-Chantar, ML
BIOMEDICINES
2021

Glutamine, fatty liver disease and aging
Simon, J;Martinez-Chantar, ML;Delgado, TC
AGING-US
2021

Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Iloro, I;Azkargorta, M;Elortza, F;Izquierdo, R;Gurruchaga, M;Goni, I;Suay, J
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
2021

The phenotypic and genetic spectrum of patients with heterozygous mutations in cyclin M2 (CNNM2)
Franken, GAC;Muller, D;Mignot, C;Keren, B;Levy, J;Tabet, AC;Germanaud, D;Tejada, MI;Kroes, HY;Nievelstein, RAJ;Brimble, E;Ruzhnikov, M;Claverie-Martin, F;Szczepanska, M;Cuk, M;Latta, F;Konrad, ...
HUMAN MUTATION
2021

Revisiting the Role of Natural Killer Cells in Non-Alcoholic Fatty Liver Disease
Martinez-Chantar, ML;Delgado, TC;Beraza, N
FRONTIERS IN IMMUNOLOGY
2021

A computer-guided design tool to increase the efficiency of cellular conversions
Jung, S;Appleton, E;Ali, M;Church, GM;del Sol, A
NATURE COMMUNICATIONS
2021

Toward Enantiomerically Pure beta-Seleno-alpha-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines
Oroz, P;Navo, CD;Avenoza, A;Busto, JH;Corzana, F;Jimenez-Oses, G;Peregrina, JM
ORGANIC LETTERS
2021

The Phosphatidyl-myo-Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo
Boldrin, F;Anso, I;Alebouyeh, S;Sevilla, IA;Geijo, M;Garrido, JM;Marina, A;Mazzabo, LC;Segafreddo, G;Guerin, ME;Manganelli, R;Prados-Rosales, R
JOURNAL OF BACTERIOLOGY
2021

Adipocyte-derived extracellular vesicles regulate survival and function of pancreatic beta cells
Gesmundo, I;Pardini, B;Gargantini, E;Gamba, G;Birolo, G;Fanciulli, A;Banfi, D;Congiusta, N;Favaro, E;Deregibus, MC;Togliatto, G;Zocaro, G;Brizzi, MF;Luque, RM;Castano, JP;Bocchiotti, MA;Arolfo, ...
JCI INSIGHT
2021

In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation
Revuelta, M;Elicegui, A;Scheuer, T;Endesfelder, S;Buhrer, C;Moreno-Cugnon, L;Matheu, A;Schmitz, T
AGING-US
2021

Synthesis and chelation study of a fluoroionophore and a glycopeptide based on an aza crown iminosugar structure
Bordes, A;Poveda, A;Fontelle, N;Arda, A;Guillard, J;Bin Ruan, Y;Marrot, J;Imaeda, S;Kato, A;Desire, J;Xie, J;Jimenez-Barbero, J;Bleriot, Y
CARBOHYDRATE RESEARCH
2021

Bovine Neutrophils Release Extracellular Traps and Cooperate With Macrophages in Mycobacterium avium subsp. paratuberculosis clearance In Vitro
Ladero-Aunon, I;Molina, E;Holder, A;Kolakowski, J;Harris, H;Urkitza, A;Anguita, J;Werling, D;Elguezabal, N
FRONTIERS IN IMMUNOLOGY
2021

LUZP1 Controls Cell Division, Migration and Invasion Through Regulation of the Actin Cytoskeleton
Bozal-Basterra, L;Gonzalez-Santamarta, M;Muratore, V;Martin-Martin, N;Ercilla, A;Rodriguez, JA;Carracedo, A;Sutherland, JD;Barrio, R
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021

Extracellular vesicles in the context of Mycobacterium tuberculosis infection
Palacios, A;Gupta, S;Rodriguez, GM;Prados-Rosales, R
MOLECULAR IMMUNOLOGY
2021

The two domains of human galectin-8 bind sialyl- and fucose-containing oligosaccharides in an independent manner. A 3D view by using NMR
Gomez-Redondo, M;Delgado, S;Nunez-Franco, R;Jimenez-Oses, G;Arda, A;Jimenez-Barbero, J;Gimeno, A
RSC CHEMICAL BIOLOGY
2021

Dynamic Intracellular Metabolic Cell Signaling Profiles During Ag-Dependent B-Cell Differentiation
Diez, P;Perez-Andres, M;Bogsted, M;Azkargorta, M;Garcia-Valiente, R;Degano, RM;Blanco, E;Mateos-Gomez, S;Barcena, P;Santa Cruz, S;Gongora, R;Elortza, F;Landeira-Vinuela, A;Juanes-Velasco, P;Segura, ...
FRONTIERS IN IMMUNOLOGY
2021

Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations
Quintana, JI;Delgado, S;Nunez-Franco, R;Canada, FJ;Jimenez-Oses, G;Jimenez-Barbero, J;Arda, A
FRONTIERS IN CHEMISTRY
2021

Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures
Campanero-Rhodes, MA;Kalograiaki, I;Euba, B;Llobet, E;Arda, A;Jimenez-Barbero, J;Garmendia, J;Solis, D
BIOMOLECULES
2021

Influence of calcium ion-modified implant surfaces in protein adsorption and implant integration
Anitua, E;Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Azkargorta, M;Elortza, F;Gurruchaga, M;Goni, I;Suay, J;Tejero, R
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
2021

Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals
Egia-Mendikute, L;Bosch, A;Prieto-Fernandez, E;Lee, SY;Jimenez-Lasheras, B;del Rio, AG;Antonana-Vildosola, A;Bruzzone, C;Bizkarguenaga, M;Embade, N;Gil-Redondo, R;Martinez-Chantar, ML;Lopez-Hoyos, ...
COMMUNICATIONS BIOLOGY
2021

The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase
Olazabal-Herrero, A;Bilbao-Arribas, M;Carlevaris, O;Sendino, M;Varela-Martinez, E;Jugo, BM;Berra, E;Rodriguez, JA
FEBS JOURNAL
2021

Evolution of DNA methylation in the human brain
Jeong, H;Mendizabal, I;Berto, S;Chatterjee, P;Layman, T;Usui, N;Toriumi, K;Douglas, C;Singh, D;Huh, I;Preuss, TM;Konopka, G;Yi, SV
NATURE COMMUNICATIONS
2021

Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins
Lima, CDL;Coelho, H;Gimeno, A;Trovao, F;Diniz, A;Dias, JS;Jimenez-Barbero, J;Corzana, F;Carvalho, AL;Cabrita, EJ;Marcelo, F
CHEMISTRY-A EUROPEAN JOURNAL
2021

Enzymatic Synthesis of Phloretin alpha-Glucosides Using a Sucrose Phosphorylase Mutant and its Effect on Solubility, Antioxidant Properties and Skin Absorption
Gonzalez-Alfonso, JL;Ubiparip, Z;Jimenez-Ortega, E;Poveda, A;Alonso, C;Coderch, L;Jimenez-Barbero, J;Sanz-Aparicio, J;Ballesteros, AO;Desmet, T;Plou, FJ
ADVANCED SYNTHESIS & CATALYSIS
2021

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation
Schijns, V;Majhen, D;van der Ley, P;Thakur, A;Summerfield, A;Berisio, R;Nativi, C;Fernandez-Tejada, A;Alvarez-Dominguez, C;Gizurarson, S;Zamyatina, A;Molinaro, A;Rosano, C;Jakopin, Z;Gursel, ...
PHARMACEUTICS
2021

FOXA1 mutations influence the therapeutic response of breast cancer by altering chromatin state
Arruabarrena-Aristorena, A;Toska, E
MOLECULAR & CELLULAR ONCOLOGY
2021

Computational modelling of stem cell-niche interactions facilitates discovery of strategies to enhance tissue regeneration and counteract ageing
Potapov, I;Garcia-Prat, L;Ravichandran, S;Munoz-Canoves, P;del Sol, A
FEBS JOURNAL
2021

Biotin-phenosafranin as a new photosensitive conjugate for targeted therapy and imaging
Blauz, A;Rychlik, B;Plazuk, D;Peccati, F;Jimenez-Oses, G;Steinke, U;Sierant, M;Trzeciak, K;Skorupska, E;Miksa, B
NEW JOURNAL OF CHEMISTRY
2021

Origin and Control of Chemoselectivity in Cytochrome c Catalyzed Carbene Transfer into Si-H and N-H bonds
Garcia-Borras, M;Kan, SBJ;Lewis, RD;Tang, A;Jimenez-Oses, G;Arnold, FH;Houk, KN
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2021

Selective modulation by PARP-1 of HIF-1 alpha-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions
Marti, JM;Garcia-Diaz, A;Delgado-Bellido, D;O'Valle, F;Gonzalez-Flores, A;Carlevaris, O;Rodriguez-Vargas, JM;Ame, JC;Dantzer, F;King, GL;Dziedzic, K;Berra, E;de Alava, E;Amaral, AT;Hammond, ...
REDOX BIOLOGY
2021

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear
Ferreira, NC;Charco, JM;Plagenz, J;Orru, CD;Denkers, ND;Metrick, MA;Hughson, AG;Griffin, KA;Race, B;Hoover, EA;Castilla, J;Nichols, TA;Miller, MW;Caughey, B
SCIENTIFIC REPORTS
2021

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Erdbrugger, U;Blijdorp, CJ;Bijnsdorp, IV;Borras, FE;Burger, D;Bussolati, B;Byrd, JB;Clayton, A;Dear, JW;Falcon-Perez, JM;Grange, C;Hill, AF;Holthofer, H;Hoorn, EJ;Jenster, G;Jimenez, CR;Junker, ...
JOURNAL OF EXTRACELLULAR VESICLES
2021

Cosolute modulation of protein oligomerization reactions in the homeostatic timescale
Mateos, B;Bernardo-Seisdedos, G;Dietrich, V;Zalba, N;Ortega, G;Peccati, F;Jimenez-Oses, G;Konrat, R;Tollinger, M;Millet, O
BIOPHYSICAL JOURNAL
2021

Trimethylamine N-oxide is a new plant molecule that promotes abiotic stress tolerance
Catala, R;Lopez-Cobollo, R;Berbis, MA;Jimenez-Barbero, J;Salinas, J
SCIENCE ADVANCES
2021

Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
Cerqueira, A;Romero-Gavilan, F;Garcia-Arnaez, I;Martinez-Ramos, C;Ozturan, S;Izquierdo, R;Azkargorta, M;Elortza, F;Gurruchaga, M;Suay, J;Goni, I
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
2021

Enthalpy-Entropy Compensation in Biomolecular Recognition: A Computational Perspective
Peccati, F;Jimenez-Oses, G
ACS OMEGA
2021

Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
Prieto-Fernandez, E;Egia-Mendikute, L;Vila-Vecilla, L;Bosch, A;Barreira-Manrique, A;Lee, SY;Garcia-del Rio, A;Antonana-Vildosola, A;Jimenez-Lasheras, B;Moreno-Cugnon, L;Jimenez-Barbero, J;Berra, ...
EMERGING MICROBES & INFECTIONS
2021

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs
Zolotarov, Y;Ma, C;Gonzalez-Recio, I;Hardy, S;Franken, GAC;Uetani, N;Latta, F;Kostantin, E;Boulais, J;Thibault, MP;Cote, JF;Moreno, ID;Quintana, AD;Hoenderop, JGJ;Martinez-Cruz, LA;Tremblay, ...
CELLULAR AND MOLECULAR LIFE SCIENCES
2021

Could protein content of Urinary Extracellular Vesicles be useful to detect Cirrhosis in Alcoholic Liver Disease?
Gonzalez, E;Azkargorta, M;Garcia-Vallicrosa, C;Prieto-Elordui, J;Elortza, F;Blanco-Sampascual, S;Falcon-Perez, JM
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2021