Publications

2019

VE-cadherin promotes vasculogenic mimicry by modulating kaiso-dependent gene expression
Delgado-Bellido, D;Fernandez-Cortes, M;Rodriguez, MI;Serrano-Saenz, S;Carracedo, A;Garcia-Diaz, A;Oliver, FJ
Cell death and differentiation
2019

Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease
Blokker, BA;Maijo, M;Echeandia, M;Galduroz, M;Patterson, AM;Ten, A;Philo, M;Schungel, R;Gutierrez-de Juan, V;Halilbasic, E;Fuchs, C;Le Gall, G;Milkiewicz, M;Milkiewicz, P;Banales, JM;Rushbrook, ...
Hepatology
2019

ANP32E, a Protein Involved in Steroid-Refractoriness in Ulcerative Colitis, Identified by a Systems Biology Approach
Loren, V;Garcia-Jaraquemada, A;Naves, JE;Carmona, X;Manosa, M;Aransay, AM;Lavin, JL;Sanchez, I;Cabre, E;Manye, J;Domenech, E
J Crohns Colitis
2019

The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
Romero-Gavilan, F;Araujo-Gomes, N;Garcia-Arnaez, I;Martinez-Ramos, C;Elortza, F;Azkargorta, M;Iloro, I;Gurruchaga, M;Suaya, J;Goni, I
Colloids and surfaces. B, Biointerfaces
2019

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs
Pabis, Marta; Popowicz, Grzegorz M; Stehle, Ralf; Fernandez-Ramos, David; Asami, Sam; Warner, Lisa; Garcia-Maurino, Sofia M; Schlundt, Andreas; Martinez-Chantar, Maria L; Diaz-Moreno, Irene; ...
Nucleic acids research
2019

Unveiling the olfactory proteostatic disarrangement in Parkinson's disease by proteome-wide profiling
Lachen-Montes, M;Gonzalez-Morales, A;Iloro, I;Elortza, F;Ferrer, I;Gveric, D;Fernandez-Irigoyen, J;Santamaria, E
Neurobiology of aging
2019

Bacterial tannases: classification and biochemical properties
de las Rivas, B;Rodriguez, H;Anguita, J;Munoz, R
Applied microbiology and biotechnology
2019

NADH dehydrogenase complex I is overexpressed in incipient metastatic murine colon cancer cells
Marquez, J;Kratchmarova, I;Akimov, V;Unda, F;Ibarretxe, G;Clerigue, AS;Osinalde, N;Badiola, I
Oncology reports
2019

Novel Dextran-Supported Biological Probes Decorated with Disaccharide Entities for Investigating the Carbohydrate-Protein Interactions of Gal-3
Rahkila, J;Ekholm, FS;Arda, A;Delgado, S;Savolainen, J;Jimenez-Barbero, J;Leino, R
Chembiochem : a European journal of chemical biology
2019

The interaction of lipid-liganded gold clusters (Aurora (TM)) with lipid bilayers
Sot, J;Mendanha-Neto, SA;Busto, JV;Garcia-Arribas, AB;Li, SR;Burgess, SW;Shaw, WA;Gil-Carton, D;Goni, FM;Alonso, A
Chemistry and physics of lipids
2019

Listeria monocytogenes virulence factors, including listeriolysin O, are secreted in biologically active extracellular vesicles
Coelho, C;Brown, L;Maryam, M;Vij, R;Smith, DFQ;Burnet, MC;Kyle, JE;Heyman, HM;Ramirez, J;Prados-Rosales, R;Lauvau, G;Nakayasu, ES;Brady, NR;Hamacher-Brady, A;Coppens, I;Casadevall, A
The Journal of biological chemistry
2019

Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain
Cabrera, Y;Dublang, L;Fernandez-Higuero, JA;Albesa-Jove, D;Lucas, M;Viguera, AR;Guerin, ME;Vilar, JMG;Muga, A;Moro, F
journal of molecular biology
2019

beta-Glucan as an immune activator and a carrier in the construction of a synthetic MUC1 vaccine
Wang, HX;Yang, B;Wang, YL;Liu, F;Fernandez-Tejada, A;Dong, SW
Chemical communications (Cambridge, England)
2019

The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers
Yang, JW;Murray, B;Barbier-Torres, L;Liu, T;Liu, ZQ;Yang, HP;Fan, W;Wang, JH;Li, Y;Seki, E;Mato, JM;Lu, SC
The Journal of biological chemistry
2019

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
Zubiete-Franco, I;Garcia-Rodriguez, JL;Lopitz-Otsoa, F;Serrano-Macia, M;Simon, J;Fernandez-Tussy, P;Barbier-Torres, L;Fernandez-Ramos, D;Gutierrez-de-Juan, V;de Davalillo, SL;Carlevaris, O;Gomez, ...
EBioMedicine
2019

Post-transcriptional regulation by cytosine-5 methylation of RNA
Garcia-Vilchez, R;Sevilla, A;Blanco, S
Biochimica et biophysica acta. Gene regulatory mechanisms
2019

Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib
Al-Abdulla, R;Lozano, E;Macias, RIR;Monte, MJ;Briz, O;O'Rourke, CJ;Serrano, MA;Banales, JM;Avila, MA;Martinez-Chantar, ML;Geier, A;Andersen, JB;Marin, JJG
British journal of pharmacology
2019

Modification of the glycosylation of extracellular vesicles alters their biodistribution in mice
Royo, F;Cossio, U;de Angulo, AR;Llop, J;Falcon-Perez, JM
Nanoscale
2019

A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells
Domenici, G;Aurrekoetxea-Rodriguez, I;Simoes, BM;Rabano, M;Lee, SY;San Millan, J;Comaills, V;Oliemuller, E;Lopez-Ruiz, JA;Zabalza, I;Howard, BA;Kypta, RM;Vivanco, MD
Oncogene
2019

In My Element: Fluorine
Jimenez-Barbero, J
CHEMISTRY-A EUROPEAN JOURNAL
2019

The Prion 2018 round tables (II): A beta, tau, alpha-synuclein horizontal ellipsis are they prions, prion-like proteins, or what?
Erana, H
PRION
2019

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties
Cochet, F;Facchini, FA;Zaffaroni, L;Billod, JM;Coelho, H;Holgado, A;Braun, H;Beyaert, R;Jerala, R;Jimenez-Barbero, J;Martin-Santamaria, S;Peri, F
SCIENTIFIC REPORTS
2019

3-Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L-Serine Synthesis
Paczia, N;Becker-Kettern, J;Conrotte, JF;Cifuente, JO;Guerin, ME;Linster, CL
BIOCHEMISTRY
2019

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease
Bobeica, SC;Dong, SH;Huo, LJ;Mazo, N;McLaughlin, MI;Jimenez-Oses, G;Nair, SK;van der Donk, WA
ELIFE
2019

Differences in the metabolite composition and mechanical properties of extracellular vesicles secreted by hepatic cellular models
Royo, F;Gil-Carton, D;Gonzalez, E;Mleczko, J;Palomo, L;Perez-Cormenzana, M;Mayo, R;Alonso, C;Falcon-Perez, JM
JOURNAL OF EXTRACELLULAR VESICLES
2019

Surface Attachment Enhances the Thermodynamic Stability of ProteinL
Ortega, G;Kurnik, M;Dauphin-Ducharme, P;Li, H;Arroyo-Curras, N;Caceres, A;Plaxco, KW
Angewandte Chemie
2019

Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents
Bernardim, B;Matos, MJ;Ferhati, X;Companon, I;Guerreiro, A;Akkapeddi, P;Burtoloso, ACB;Jimenez-Oses, G;Corzana, F;Bernardes, GJL
NATURE PROTOCOLS
2019

Raman tweezers microspectroscopy of circa 100 nm extracellular vesicles
Kruglik, SG;Royo, F;Guigner, JM;Palomo, L;Seksek, O;Turpin, PY;Tatischeff, I;Falcon-Perez, JM
NANOSCALE
2019

Structural basis for assembly of vertical single beta-barrel viruses
Santos-Perez, I;Charro, D;Gil-Carton, D;Azkargorta, M;Elortza, F;Bamford, DH;Oksanen, HM;Abrescia, NGA
NATURE COMMUNICATIONS
2019

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain
Kalamakis, G;Brune, D;Ravichandran, S;Bolz, J;Fan, WQ;Ziebell, F;Stiehl, T;Catala-Martinez, F;Kupke, J;Zhao, S;Llorens-Bobadilla, E;Bauer, K;Limpert, S;Berger, B;Christen, U;Schmezer, P;Mallm, ...
CELL
2019

Fatty Acid Compositions of Ceramides and Sphingomyelins in Mammalian Tissues and Cultured Cells
Goni, FM;Manni, MM;Sot, J;Arretxe, E;Gil-Redondo, R;Falcon, J;Balgoma, D;Alonso, C;Alonso, A
BIOPHYSICAL JOURNAL
2019

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage
Companon, I;Guerreiro, A;Mangini, V;Castro-Lopez, J;Escudero-Casao, M;Avenoza, A;Busto, JH;Castillon, S;Jimenez-Barbero, J;Asensio, JL;Jimenez-Oses, G;Boutureira, O;Peregrina, JM;Hurtado-Guerrero, ...
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
2019

Chitosan nanogels as nanocarriers of polyoxometalates for breast cancer therapies
Perez-Alvarez, L;Ruiz-Rubio, L;Artetxe, B;Vivanco, MDM;Gutierrez-Zorrilla, JM;Vilas-Vilela, JL
CARBOHYDRATE POLYMERS
2019

Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer
Cui, B;Eyers, PA;Dobens, LL;Tan, NS;Mace, PD;Link, WA;Kiss-Toth, E;Keeshan, K;Nakamura, T;Pear, WS;Feseha, Y;Johnston, J;Carracedo, A;Scheideler, M;Llyas, Z;Bauer, RC;Erusalimsky, JD;Grzesik, ...
ACTA PHARMACEUTICA SINICA B
2019

Unraveling the Molecular Details of the Complete Mechanism That Governs the Synthesis of Prostaglandin G2 Catalyzed by Cyclooxygenase-2
Cebrian-Prats, A;Gonzalez-Lafont, A;Lluch, JM
ACS OMEGA
2019

Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
Cabre, G;Garrido-Charles, A;Moreno, M;Bosch, M;Porta-de-la-Riva, M;Krieg, M;Gascon-Moya, M;Camarero, N;Gelabert, R;Lluch, JM;Busque, F;Hernando, J;Gorostiza, P;Alibes, R
NATURE COMMUNICATIONS
2019

The p12 subunit of human polymerase uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)
Gonzalez-Magana, A;de Opakua, AI;Romano-Moreno, M;Murciano-Calles, J;Merino, N;Luque, I;Rojas, AL;Onesti, S;Blanco, FJ;De Biasio, A
JOURNAL OF BIOLOGICAL CHEMISTRY
2019

Tetraspanin-decorated extracellular vesicle-mimetics as a novel adaptable reference material.
Lozano-Andres, Estefania;Libregts, Sten F;Toribio, Victor;Royo, Felix;Morales, Sara; Lopez-Martin, Soraya;Vales-Gomez, Mar;Reyburn, Hugh T;Falcon-Perez, Juan Manuel;Wauben, Marca H;Soto, Manuel;Yanez-Mo, ...
Journal of extracellular vesicles
2019

Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
Klontz, EH;Trastoy, B;Deredge, D;Fields, JK;Li, C;Orwenyo, J;Marina, A;Beadenkopf, R;Gunther, S;Flores, J;Wintrode, PL;Wang, LX;Guerin, ME;Sundberg, EJ
ACS CENTRAL SCIENCE
2019

Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis
Reverter, E;Lozano, JJ;Alonso, C;Berzigotti, A;Seijo, S;Turon, F;Baiges, A;Martinez-Chantar, ML;Mato, JM;Martinez-Arranz, I;La Mura, V;Hernandez-Gea, V;Bosch, J;Garcia-Pagan, JC
LIVER INTERNATIONAL
2019

Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators
Gimenez-Mascarell, P;Gonzalez-Recio, I;Fernandez-Rodriguez, C;Oyenarte, I;Muller, D;Martinez-Chantar, ML;Martinez-Cruz, LA
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019

PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis
Dissmeyer, N;Coux, O;Rodriguez, MS;Barrio, R
TRENDS IN BIOCHEMICAL SCIENCES
2019

The N-glycan structures of the antigenic variants of chlorovirus PBCV-1 major capsid protein help to identify the virus-encoded glycosyltransferases
Speciale, I;Duncan, GA;Unione, L;Agarkova, IV;Garozzo, D;Jimenez-Barbero, J;Lin, S;Lowary, TL;Molinaro, A;Noel, E;Laugieri, ME;Tonetti, MG;Van Etten, JL;De Castro, C
JOURNAL OF BIOLOGICAL CHEMISTRY
2019

Metabolic implications of methionine adenosyltransferase 1A depletion during fasting
Ramos, DF;Mosca, L;Goikoetxea, N;Serrano-Macia, M;Delgado, TC;Otsoa, FL;de Juan, VG;de Urturi, DS;Gonzalez-Romero, F;Ruiz-Nunez, A;Falcon-Perez, J;Woodhoo, A;Apichueta, P;Lu, SC;Mato, JM;Martinez-Chantar, ...
JOURNAL OF HEPATOLOGY
2019

Targeting NEDDylation protects liver from acute drug-induced damage
Simon, J;Ramos, DF;de Juan, VG;Serrano-Macia, M;Goikoetxea, N;de Urturi, DS;Agudo, RR;Otsoa, FL;de Davalillo, SL;Buque, X;Varela-Rey, M;Fernandez-Tussy, P;Aspichueta, P;Delgado, TC;Martinez-Chantar, M
JOURNAL OF HEPATOLOGY
2019

Sumoylation/acetylation drives forward oncogenic role of LKB1 in Liver
Otsoa, FL;Zubiete-FRanco, I;Rodriguez, JLG;Serrano-Macia, M;Simon, J;Tussy, PF;Torres, LB;Fernandez-Ramos, D;de Juan, VG;de Davalillo, SL;Carlevaris, O;Gomez, AB;Arrizabalaga, J;Calvisi, DF;Martin, ...
JOURNAL OF HEPATOLOGY
2019

NEDDylation inhibition as a new potential therapy of nonalcoholic fatty liver disease
Serrano-Macia, M;Azkargorta, M;Simon, J;Otsoa, FL;Delgado, TC;Ramos, DF;de Juan, VG;Varela-Rey, M;Goikoetxea, N;Tussy, PF;Apichueta, P;de Urturi, DS;Buque, X;Iruzubieta, P;Crespo, J;Lu, SC;Mato, ...
JOURNAL OF HEPATOLOGY
2019

Role of methylation-controlled J-protein, endogenous repressor of the mitochondrial respiratory chain, in cholestatic liver disease
Iruzubieta, P;Barbier-Torres, L;Goikoetxea, N;Delgado, TC;Ramos, DF;Varela-Rey, M;de Juan, VG;Tussy, PF;Zubiete-Franco, I;Simon, J;Congregado, DM;Otsoa, FL;Santos, BG;Buque, X;Lopez-Hoyos, M;Apichueta, ...
JOURNAL OF HEPATOLOGY
2019

Mitochondrial GNMT-complex II is recovered by miR-873-5p targeting in NAFLD
Ramos, DF;Tussy, PF;Otsoa, FL;Simon, J;Torres, LB;Santos, BG;Nunez, M;Azkargorta, M;de Juan, VG;Serrano-Macia, M;Agudo, RR;Champagne, DG;Iruzubieta, P;Anguita, J;Rincon, M;Elortza, F;Anita, ...
JOURNAL OF HEPATOLOGY
2019

Aramchol, SCD1 inhibitor, improves liver glucose homeostasis in NASH
Mato, JM;delaCruz-Villar, L;Fernandez-Ramos, D;Lopitz, F;Azkargorta, M;Elortza, F;Iruarrizaga-Lejarreta, M;Alonso, C;Barbier-Torres, L;Lu, SC;Hayardeny, L;Gorfine, T;Sanyal, AJ
JOURNAL OF HEPATOLOGY
2019

The nuclear factor TCF20 regulates the severity of liver fibrosis in mice
Cordoba-Jover, B;Ribera, J;Portoles, I;Sandalinas, S;Elortza, F;Pujol, A;Jimenez, W;Morales-Ruiz, M
JOURNAL OF HEPATOLOGY
2019

E2F2 mediated repression of fatty acid B-oxidation is mitigated through CREB1 in progressive non-alcoholic fatty liver disease
Gonzalez-Romero, F;Mestre, D;Aurrekoetxea, I;de Urturi, DS;Gomez-Santos, B;Nunez-Garcia, M;Buque, X;Delgado, I;Palomo-Irigoyen, M;Tamayo-Caro, M;Woodhoo, A;Varela-Rey, M;Martinez-Chantar, ML;Iglesias, ...
JOURNAL OF HEPATOLOGY
2019

Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma and primary sclerosing cholangitis
Banales, JM;Inarrairaegui, M;Arbelaiz, A;Milkiewicz, P;Muntane, J;Munoz-Bellvis, L;La Casta, A;Gonzalez, LM;Arretxe, E;Alonso, C;Martinez-Arranz, I;Lapitz, A;Santos-Laso, A;Avila, MA;Martinez-Chantar, ...
JOURNAL OF HEPATOLOGY
2019

Dual targeting of G9a and DNM-methyltransferase-1 for the treatment of experimental cholangiocarcinoma
Colyn, L;Alvarez-Sola, G;Latasa, MU;Uriarte, I;Barcena-Varela, M;Arechederra, M;Jimenez, M;Morini, S;Carotti, S;Oyarzabal, J;Prosper, F;Canale, M;Gardini, AC;Elizalde, MI;Urman, J;Chen, C;Cubero, ...
JOURNAL OF HEPATOLOGY
2019

MCJ: A therapeutic target in hepatic ischemia and reperfusion injury
Goikoetxea, N;Ramos, DF;Serrano-Macia, M;Cornide, ME;Jimenez-Castro, M;Alfano, B;de Urturi, DS;Gonzalez-Romero, F;de Juan, VG;Iruretagoyena, BR;Delgado, TC;Otsoa, FL;Torres, LB;Tussy, PF;Simon, ...
JOURNAL OF HEPATOLOGY
2019

Azabicyclic vinyl sulfones for residue-specific dual protein labelling Electronic supplementary information (ESI) available: Detailed methods and additional characterisation. See DOI: 10.1039/c9sc00125e
de Montes, EG;Jimenez-Moreno, E;Oliveira, BL;Navo, CD;Cal, PMSD;Jimenez-Oses, G;Robina, I;Moreno-Vargas, AJ;Bernardes, GJL
CHEMICAL SCIENCE
2019

Serum IgM Glycosylation Associated with Tuberculosis Infection in Mice
Kumagai, T;Palacios, A;Casadevall, A;Garcia, MJ;Toro, C;Tiemeyer, M;Prados-Rosales, R
MSPHERE
2019

An integrative method to predict signalling perturbations for cellular transitions
Zaffaroni G1, Okawa S1,2, Morales-Ruiz M3,4,5,6, Del Sol A1,7,8.
nucleic acids research
2019

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities.
Okawa, Satoshi; Del Sol, Antonio
nucleic acids research
2019

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy
Del Sol A, Okawa S, Ravichandran S.
Trends in biotechnology
2019