HE strategy


European Commission

CIC bioGUNE Strategic Plan for Research and Innovation is designed to provide the framework that allows CIC bioGUNE scientists to perform high-quality interdisciplinary scientific research that reaches society, attracts talent and external funding, and permits the center to be internationally recognized.

The alignment with the Plan for Science, Technology and Innovation Euskadi 2030 (PCTI 2030) and the European Research Framework program Horizon Europe, guides the Strategic Plan of CIC bioGUNE towards research of excellence in the field of life sciences. Focus on Personalized Medicine, CIC bioGUNE covers the entire R&D value chain, including technology transfer and commercial exploitation of the scientific results.

CIC bioGUNE emphasizes the effective co-ordination between the different societal stakeholders and rationalizes the available resources providing defined strategies to foster initiatives between private and public actors of different governance levels.

Therefore, with our Strategic Plan for Horizon Europe, we are committed to Excellence Science, Global Challenges, Industrial Competitiveness and strengthening the European Research Area. We fully unroll the potential of our research breakthroughs for the wellbeing of Society.

Excellent Science

  • Isotopically labelling of cell surface glycans to illuminate infectious processes at atomic resolution - Glyco13Cell
    Luca Unione: Starting Grant
  • Minimal saponin-based adjuvant vaccine platform - ADJU-PLATFORM
    Alberto Fernández Tejada: Proof of Concept
  • Development of a marketable adjuvant candidate for vaccine applications - ADJUVACCINE
    Alberto Fernández Tejada: Proof of Concept
  • Development of a first-in-class inhibitor of FIH for cancer immunotherapy - FIH-IO
    Asís Palazón: Proof of Concept

Marie Skłodowska-Curie actions (MSCA) Marie Curie Actions

Postdoctoral Fellowships (TN)

  • Structural exploration of GD3 ganglioside-COVID spike Protein Interaction and siglec-7 Role in inhibition of virAL infection - SPIRAL
    Iris Alicia Bermejo
  • Epithelial Memory to Candida albicans during commensalism and infection - EPIMemory
    Aize Pellón
  • Magnesium and fetal metabolic programming: an approach to preventing a life-cycle of metabolic diseases - MagFetProg
    Giselle Adriana Abruzzese

Doctoral Networks (TN)

  • GLYCOprotein N-glycosylation from non-life to eukaryotes: a Doctoral Network to expand the knowledge on a ubiquitous posttranslational modification of proteins - GLYCO-N
    Jesús Jiménez-Barbero
  • European Network on the Supramolecular Chemistry of Carbohydrates - ENSCC
    Ana Ardá

Staff Exchange

  • Human ECM-based platform for anti-cancer drug testing - CARES (CAncer dRug tESting) - CARES
    María dM Vivanco (Coordinator)

Research Infraestructures

  • Remote NMR: Moving NMR infrastructures to remote access capabilities – R-RMN
    Óscar Millet

Global Challenges & European Industrial Competitiveness

  • Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH (non-alcoholic steatohepatitis) transition to inform early prevention and treatment strategies - Halt-RONIN
    Juan Manuel Falcón
Digital, Industry and Space
  • AI-Enabled Data Lifecycles Optimization and Data Spaces Integration for Increased Efficiency and Interoperability - PLIADES
    Óscar Millet
Food, Bioeconomy, Natural Resources, Agriculture & Environment
  • Improved control of priority animal diseases: Novel vaccines and companion diagnostic tests for African horse sickness, peste des petits ruminants and foot-and-mouth disease - SPIDVAC
    Nicola GA Abrescia
  • Combatting diet related non-communicable disease through enhanced surveillance - CoDiet
    Óscar Millet

Widening participation and strengthening the European Research Area

Widening participation & spreading excellence
  • Centre for Excellence in Diagnostic and Advanced Therapeutics based on Extracellular Vesicles - EVCA
    Juan Manuel Falcón
  • Building Networks to Excel in Glycosciences - GLYCOTwinning
    Jesús Jiménez Barbero

IINTERREG EUROPE European Commission

Interreg POCTEFA
  • Cooperación Transfronteriza para la Investigación de Enfermedades Neurodegenerativas - NEURO-COOP
    Joaquín Castilla
Interreg Atlantic Area
  • Blue Organoids for Treatment Selection - BOTS
    María dM Vivanco


Joint Programming Initiative - Healthy Diet for a Healthy life (JPI HDHL)
  • Genetic Carbohydrate Maldigestion as a model to study food Hypersensitivity Mechanism and Guide Personalised Treatment using a Non-invasive Multiparametric Test - GenMalCarb
    Mauro D´Amato
EU Joint Programme – Neurodegenerative Disease Research (JPND Research)
  • Prodromal biomarkers in fatal familial insomnia: a longitudinal study in humans and mice - ProFFIle
    Joaquín Castilla


Excellent Science

  • Breaking the limits in glycan recognition by NMR - RECGLYCANMR
    Jesús Jiménez Barbero: Advanced Grant
  • Targeting the adaptive capacity of prostate cancer through the manipulation of transcriptional and metabolic traits - CancerADAPT
    Arkaitz Carracedo: Consolidator Grant
  • Exploiting the hypoxia response in T cells for Next Generation Immuno-Oncology - NextGen IO
    Asís Palazón: Starting Grant
  • Elucidating the Molecular Mechanisms of Synthetic Saponin Adjuvants and Development of Novel Self-Adjuvanting Vaccines - Adjuv-ant Vaccines
    Alberto Fernández Tejada: Starting Grant
  • A metabolism bases prognostic biomarker for prostate cancer - MetaboMARKER
    Arkaitz Carracedo: Proof of Concept
  • Metabolic Requirements for prostate cancer cell fitness - Cancermetab
    Arkaitz Carracedo: Starting Grant

Marie Skłodowska-Curie actions Marie Curie Actions

Individual Fellowship
  • Probing CD28 as checkpoint for T cell co-stimulation in cancer and infection - CD28
    Pablo Valderde (Standard European Fellowship)
  • Target identification and elucidation of the molecular mechanism of action of saponin vaccine adjuvants QS-21 - QS21Mech
    Abhijit Saha (Standard European Fellowship)
  • Chemoenzymatic glyco-engineering of therapeutic monoclonal antibodies (GlycoMabs)
    Beatriz Trastoy (European Reintegration Fellowship)
  • First Chemoselective Synthesis and Structural Studies of Lasso Peptides - FCSSSLP)
    Javier López Ogalla (Global Fellowship)
  • Novel vaccine and diagnostic strategies against Schmallenberg virus - SchmaVirusVacDiag)
    Hani Yousef (European Standard Fellowship)
  • Cholesterol metabolism as a driver of prostate cancer aggressiveness - ACM
    Alfredo Caro (Standard European Fellowship)
  • Implication of energy sensing pathways in prostate cancer biology - PTENLKB1
    Arkaitz Carracedo (International Reintegration Grants 7th Framework Programme)
  • Unravellin the Nascent Code: Signals sensed and transmitted by the nascent chain to acquire its functional state or reprogram gene expression - NascentCode
    Paola Fucini (Career Integration Grants 7th Framework Program)
Innovative Training Networks (TN)
  • Anti-Bacterial Innovative Vaccine Training Network - GLYTUNES
    June Ereño
  • PI3K/PTEN-related monogenic disease to understand cancer - PIPgen
    Arkaitz Carracedo
  • Anti-Bacterial Innovative Vaccine Training Network - BactiVax
    Jesús Jiménez Barbero & Juan Anguita
  • The life cycle of extracellular vesicles in prostate cancer: from biogenesis and homing, to functional relevance - proEVLifeCycle
    Juan Manuel Falcón Pérez
  • European Research Training to Decipher the Ub Code: identification of potencial biomarkers nad drug targets - UbiCODE
    Rosa Barrio
  • Tribbles Research and Innovation Network - Train
    Arkaitz Carracedo
  • A training network for the rational design of the next generation of well-defined glycoconjugate vaccines - Glycovax
    Jesús Jiménez-Barbero
  • Toll-Like Receptor 4 activation and function in diseases: an integrated chemical-biology approach - TOLLerant
    Jesús Jiménez Barbero
  • European Research Training in the Ubiquitin Proteasome System - UPStream
    Rosa Barrio (Coordinator)

Societal Challenges

Health, demografic change and wellbeing
Innovative Medicine Initiative (IMI)
  • Liver Investigation: Testing Marker Utility in Steatohepatitis - LITMUS
    José María Mato
  • Anti-tick Vaccines to Prevent Tick-borne Diseases in Europe - Antidote
    Juan Anguita (Health Innovation 7th Framework Programme)
  • Hepatic and adipose tissue and functions in the metabolic syndrome - Hepadip
    José María Mato (Life Science Health 6th Framework Programme)
7th Framework Programme – COOPERATION
  • Integration of novel NANOparticle based technology for THERapeutics and diagnosis of different types of cancer - Nanother
    Edurne Berra (Finished)
Innovative Medicine Initiative

European Partnerships

Joint Transnational Call - ERA PerMed
  • Plasma extracellular vesicles (EVs): the key for precision medicine in Glioblastoma – EV-glio
    Juan Manuel Falcón
European Joint Programme on Rare Disease (EJP RD)
  • For Improving diagnostics and the disease mechanisms of rare Hypomagnesemia in paTients with CNNM2 mutations - FIGHT-CNNM2
    Alfonso Martínez (Finished)

Interreg EUROPE

  • Red cooperativa franco-española para el análisis de proteinopatías y el desarrollo de terapias individualizadas en cánceres hematológicos - PROTEOblood
    Rosa Barrio (Finished)
  • Red de investigación transfronteriza en enfermedades priónicas humanas y animales – REDPRION
    Joaquín Castilla (Finished)

European Cooperation

European Cooperation in Science and Technology (COST)

  • European network to integrate research on intracellular proteolysis pathways in health and disease - Proteostasis
    Rosa Barrio (Chair)
European Cooperation in Science and Technology

To take part in our collaborative efforts towards H2020 strategy, please contact directly our research staff or R&D Management Office: