2022/12/21

How damaged cells inhibit muscle regeneration over lifetime

Humans have a limited capacity for self-regeneration of tissues and organs but they do keep a pool of stem cells throughout their life that can self-renew and differentiate in...

2022/12/20

Gabriel Soares Guerra will defend his PhD thesis Thursday, December 22th

Gabriel Soares Guerra will defend his PhD thesis entitled “Vaccine and structura...

2022/12/16

Jone Ibáñez Pérez will defend her PhD thesis Tuesday, December 20th

Jone Ibáñez Pérez will defend her PhD thesis entitled “...

2022/12/15

CIC bioGUNE researchers develop a new transgenic mouse that faithfully reproduces...

The work provides the scientific community with a new tool for the study of the most frequent prion diseases in humans and the most difficult to get to grips with beca...

2022/12/15

Sara Bertuzzi will defend her PhD thesis Friday, December 16th

Sara Bertuzzi will defend her PhD thesis entitled “Lectin-Glycan Interactions:...

2022/12/14

Orhi Barroso Gomila will defend his PhD thesis Thursday, December 15th

Orhi Barroso Gomila will defend his PhD thesis entitled “Development of biotin-...

2022/12/13

7 PhD Open Positions “la Caixa” Doctoral INPhINIT Incoming Fellowship Programme...

The doctoral fellowship programme INPhINIT “la Caixa” 2023 grants fellowships for talented early-stage researchers of any nationality to pursue t...

2022/12/12

Paula Oroz Mateo will defend her PhD thesis tomorrow, December 13th

Paula Oroz Mateo will defend her PhD thesis entitled “Adiciones 1,4-Conjugadas a Deshidroalaninas Quirales para la Síntesis de Aminoácidos no Naturale...

2022/12/08

2022 Introductory Week at CIC bioGUNE

5th edition of the CIC bioGUNE Introductory Week To get new doctoral candidates familiarized with the research environment of CIC bioGUNE and its facilities,...

2022/11/25

New therapeutic approach to treat paracetamol-induced fulminant liver damage

Researchers from CIC bioGUNE, CIBEREHD and New York University discover that altered magnesium levels in the liver may be a cause of liver failure due to high-dose par...

2022/11/11

Carlos Miguel Díaz Domínguez will defend his PhD thesis Friday, November 18th

Carlos Miguel Díaz Domínguez will defend his PhD thesis entitled “Estudio de la diver...

2022/11/07

CIC bioGUNE, recognized with the "Severo Ochoa Center of Excellence" distinction...

The accreditation is the highest recognition for a research center in Spain. The evaluation process has been carried out by an international scientif...

2022/10/24

Julia San Millán will defend her PhD thesis on Thursday, October 27th

Julia San Millán will defend her PhD thesis entitled “Analysis of the essentiality of phosphatidylserine decarboxylase in endocrine resistant brea...

2022/10/19

Nicanor Zalba Olaizola will defend his PhD thesis Monday, October 24th

Nicanor Zalba Olaizola will defend his PhD thesis entitled “On the effect of cosolutes and crowders in the stability and kinetic properties of prot...

2022/10/18

Irene González Recio will defend her PhD thesis Monday, October 24th

Irene González Recio will defend her PhD thesis entitled “Unveiling magnesium homeostasis in liver diseases” Monday, October 24th at 12:00H...

2022/10/17

Oscar Millet Galardonado con el Premio Bilateral Hispano-Alemán Hermanos Elhuyar...

La Sociedad Alemana de Química junto con la Real Sociedad Española de Química reconocen con el premio Bilateral Hisp...

2022/10/17

Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition...

A collaborative research from the Chemical Glycobiology and Computational Chemistry Labs at CIC bioGUNE, together with the Glycotechn...

2022/10/10

The solidarity race against breast cancer has dyed Bilbao pink again with the “Marea...

After two appointments canceled due to the pandemic, the seventh edition of the “Pink Tide” was held on Sunday 9th October. Organized annually by Acambi, (the Bis...

2022/10/10

Bilbao acoge el quinto congreso internacional de metabolismo y cáncer

Este evento científico recupera la presencialidad con su ya tradicional reunión en Bilbao. El congreso, organizado por la Asociación Europea de in...

2022/10/07

Arkaitz Carracedo, galardonado con el Premio Nacional de Investigación para jóvenes...

El Ministerio de Ciencia e Investigación ha concedido hoy este reconocimiento en el marco de los Premios Nacionales de Investigación 2022, que son el galardón más ...

2022/10/04

Jon Imanol Quintana will defend his PhD thesis tomorrow, October 5.

Jon Imanol Quintana will defend his PhD thesis entitled “NMR and molecular rec...

2022/10/03

The U.S. Alzheimer Association funds CIC bioGUNE research aimed at identifying a...

The study, which will run for the next three years, advances the hypothesis that the metabolome of central nervous system-derived exosomes could be a highly valuable t...

2022/09/23

Breast Cancer Solidarity Run-Bilbao 2022

The run against breast cancer organized every year for ACAMBI will take place next October 9th 2022

2022/09/07

A CIC bioGUNE study reveals the liver to be a target organ for SARS-CoV-2 infection

Steatosis increases vulnerability to infection by SARS-CoV-2. Metformin, a treatment for hyperglycaemia in patients with type 2 diabetes, reduces infection of ...

2022/08/22

DNA changes behind irritable bowel syndrome (IBS): state-of-the-art

Publication in Nature Reviews Gastroenterology and Hepatology by researchers at CIC bioGUNE Irritable bowel syndrome is a common condition characterized by r...

2022/07/26

Miguel Tamayo will defend his PhD thesis today, July 26.

Miguel Tamayo will defend his PhD thesis entitled “Neddylation in Schwann cell myelination” Today, Tuesday, July 26 at 11:00H. Supervisor:

2022/07/19

The SPIDVAC consortium, of which CIC bioGUNE is a member, awarded EUR 5 million to...

Thirteen European and African research centers will develop innovative vaccines against African horse sickness, peste des petits ruminants and foot-and-mouth disease.

2022/07/12

CIC bioGUNE research breaks new ground in the use of natural products containing...

The work, published in the journal Nature Chemistry, will allow the use of natural products that until now have been discarded due to their toxicity.

2022/06/16

Arkaitz Carracedo y Fàtima Crispi, ganadores de los Premios a la Investigación...

En esta cuarta edición, los premios reconocen investigaciones en cáncer y en medicina materno-fetal que ahondan en la importancia de la alimentación y la nutrición...

2022/06/06

Arkaitz Carracedo and Isabel Mendizabal receive support from the CRIS Research Programme

After a thorough selection process, CRIS Against Cancer has identified 17 outstanding researchers, 10 women and 7 men, to develop improved therapies for cancer patient...

2022/05/31

Teresa Cardoso Delgado consigue un reconocimiento en la categoria “Rising Star...

El pasado 26 de mayo la Fundación Española para el Estudio del Hígado (FEEH) y Asociación ...

2022/05/25

Researcher Alberto Fernández Tejada awarded ERC Proof of Concept grant

The European Research Council makes funds available to explore the commercial potential of research work The European Research Council (ERC) has awarded a Pr...

2022/04/28

Virginia Berasategi donates 7,414 euros to the laboratory of Arkaitz Carracedo for...

The triathlete has taken part in the "Rare but not invisible" fund-raising initiative promoting 7,500 kilometres of solidarity. The triathlete Virginia Beras...

2022/03/28

Nonalcoholic fatty liver disease subtypes exhibit distinctive cardiovascular risk...

Nonalcoholic fatty liver disease (NAFLD), a disease affecting approximately one-quarter of the world’s adult population, reflects dysfunctional hepatic lipid metabolism. An ...

2022/03/25

Ariane Schaub Clerigué will defend her PhD thesis today, March 25rd

Ariane Schaub Clerigué will defend her PhD thesis entitled “PGC1⍺-driven transcriptional control of the cell secretome in prostate cancer: molecular ...

2022/03/22

CIC bioGUNE y Tekniker renuevan su compromiso de colaboración en el campo de la...

CIC bioGUNE y el centro tecnológico Tekniker renuevan su compromiso de colaboración apostando por el desarrollo de tecnología para su aplicación al campo de la bio...

2022/03/14

A study identifies obesity-regulating molecular communication guided by blood vessels

Blood vessels seen to be key players in the development of obesity. Research has revealed a mechanism through which fat cells are instructed by cells in blood ...

2022/03/01

Discovered a new molecular interaction mechanism for SARS-Cov2

The SARS-CoV-2 Spike Glycoprotein Directly Binds Exogeneous Sialic Acids The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pa...

2022/02/07

Carmen Fernández will defend her PhD thesis this Thursday, February 10th

Carmen Fernández will defend her PhD thesis entitled “Novel surface engineering approaches for protein crystallization and structural insights int...

2022/02/07

El investigador Asís Palazón obtiene la ayuda ERC Proof of Concept

El Consejo Europeo de Investigación destina financiación a explorar el potencial comercial de trabajos de investigación. El

2022/02/02

Atlas Molecular Pharma closes a EUR 3 million round of funding to advance clinical...

SPRI becomes a shareholder of the company, a spin-off of CIC bioGUNE, together with the asset management company Inveready and the Centre for the Development of Indust...

2021/12/22

Experimental and computational synergy – Promising COVID-19 result in immunology

An international collaboration between researchers from, the Centre for Cooperative Research in Biosciences (CIC bioGUNE, Bilbao), the Luxembourg Centre for Systems Biomedicin...

2021/12/16

Diego Barriales will defend his PhD thesis on Monday, December 20th

Diego Barriales will defend his PhD thesis entitled “PLASTICITY OF MACROPHAGE ...

2021/12/13

Saray Sánchez will defend her PhD thesis today, December 13th

Saray Sánchez will defend her PhD thesis entitled “Antibody-mediated inhibition of ...

2021/12/09

Bowel habits written in the DNA: new clues for irritable bowel syndrome

In a large-scale study published in Cell Genomics, researchers studied the DNA of more than 160,000 people who provided information on the frequency of their bowel mov...

2021/11/29

Cristina Risueño will defend her PhD thesis on Wednesday, December 1st

Cristina Risueño will defend her PhD thesis entitled “Modulating the conformational plasticity of tetraspsanin CD81 by ligand-binders and its implicati...

2021/11/25

Lucia Maio will defend her PhD thesis on November 26th

Lucia Maio will defend her PhD thesis entitled “Designed metallo-tags for probing natural systems” tomorrow November 26th, at 11.30 am. ...

2021/11/23

Early-stage researchers receive training to develop innovative antibacterial vaccines

CIC bioGUNE is hosting the congress of the BactiVax Project, a European training network funded by the European Commission. The BactiVax project brin...

2021/11/18

SUMO-ID: a new tool to study the consequences of protein modifications by the ubiquitin...

Posttranslational modifications (PTM) by the members of the ubiquitin/ubiquitin-like (Ub/UbL) family are essential for cell survival and the proper function of the organism. C...

2021/11/05

Large-scale genetic study reveals new clues for the shared origins of irritable bowel...

The study, co-led by researchers from CIC bioGUNE, has analysed genetic data from over 50,000 patients. The research highlights the close relationship between ...

2021/10/28

La investigadora de CIC bioGUNE Malu Martínez Chantar galardonada como “investigadora...

El pasado 25 de octubre, La Fundación Ikerbasque y el

2021/10/20

Race Against Breast Cancer 2021

On Sunday 17th October the annual ACAMBI (Asociación de Cáncer de Mama y/o Ginecológ...

2021/10/14

Genetic defects and carbohydrate malabsorption lurking behind irritable bowel syndrome

A new study, led by researchers at CIC bioGUNE, suggests genetic defects in carbohydrates digestion may be (mis)diagnosed as IBS in some patients. Researcher...

2021/10/05

OSASUNBERRI, una iniciativa colaborativa de innovación e inversión en la industria...

OSASUNBERRI, una iniciativa colaborativa interregional de innovación e inversión en la industria d...

2021/10/04

ACAMBI run again in Bilbao!

The run against breast cancer organized every year for ACAMBI will take place next October 17th 2021

2021/09/30

Therapeutic protein silencing reduces the likelihood of liver failure in older transplant...

Hepatic ischaemia-reperfusion injury is the leading cause of early organ failure after transplant. MCJ protein silencing emerges as a new therapy to prevent li...

2021/09/17

Miguel Ángel Pérez will defend his PhD thesis TOMORROW, September 17th

Miguel Ángel Pérez will defend his PhD thesis entitled “Generación de distintas cepas de priones recombinantes como herramienta para el estudio del m...

2021/09/06

Rebeca Cuesta will defend her PhD thesis on Thursday, September 9

Rebeca Cuesta will defend her PhD thesis entitled “Structural studies of filamentous plant viruses by cryo-electron microscopy and cryo-electron tomogra...

2021/08/17

Un estudio metabolómico a gran escala permite diagnosticar el Síndrome Metabólico...

El estudio llevado a cabo por investigadores de CIC bioGUNE, publicado en la revista Cardiovascular Diabetology, ha analizado el metaboloma de la orina de más de 11.0...

2021/07/14

large-scale genetic study links carbohydrate malabsorption to irritable bowel syndrome

The study, coordinated by researchers at CIC bioGUNE and published in the journal Gastroenterology, has analysed the DNA of over 100,000 individuals.

2021/07/12

CIC bioGUNE, ONCE Foundation and Ikerbasque sign an agreement to promote the research...

The successful candidates will conduct their research at CIC bioGUNE. The aim of the collaboration agreement is to improve eq...

2021/07/06

Revisiting the role of Extracellular Vesicles secreted by hepatocytes in drug-induced...

Idiosyncratic drug-induced liver injury (DILI) constitutes a multi-layered challenge that spans the life of the drug from pre-clinical development to clinical trials and post-...

2021/07/01

New key mechanism in the development of non-alcoholic fatty liver disease identified

Alterations in neddylation have been shown to be involved in some liver diseases such as liver cancer, fibrosis and cirrhosis, and now in the development of non-alcoho...

2021/06/25

María Pía Lenza will defend her PhD thesis on Monday, June 28th

María Pía Lenza will defend her PhD thesis entitled “Deciphering the recognition features of glyc...

2021/06/18

Technologies for the analysis of single extracellular vesicles

Single-vesicle imaging and analysis methodologies focus attention towards exosomes research. Recent advances in the single-vesicle analysis have facilitated their appl...

2021/06/11

DNA changes behind Microscopic Colitis

Spotlight on microscopic colitis research at CIC bioGUNE: publication in Nature Reviews Disease Primers and prize for best basic science communication at the Spanish S...

2021/06/09

CIC bioGUNE researchers describe a new microRNA determinant of response to sorafenib...

Identification of the miR-518d-5p molecule in blood is associated with increased resistance to sorafenib treatment and reduced overall survival in patients with hepato...

2021/06/07

José Daniel Martínez Ordóñez will defend his PhD thesis thisTuesday, June 8th

José Daniel Martínez Ordóñez will defend his PhD thesis entitled “Novel lig...

2021/06/04

El Departamento de Eduación e Ikerbasque reconocen a Malu Martínez Chantar como...

El objetivo de la iniciativa es visibilizar a las mujeres investigadoras de Euskadi para que sirvan de ejemplo e inspiración a las nuevas generaciones de investigador...

2021/05/31

New miniature organ to understand human pancreas development

Understanding human pancreas during development The pancreas is a little organ behind the stomach and has two main functions – digestion and blood...

2021/05/28

Rafael López Moreno will defend his PhD Thesis Today, May28th

Rafael López Moreno will defend his PhD Thesis entitled “Estudio de la diversidad...

2021/05/19

PIPgen: a new Innovative Training Network to put PI3K/PTEN related diseases under...

The PIPgen Training Programme seeks to train the next generation of PI3K/PTEN experts and envisions to empower PI3K/PT...

2021/04/27

Inhibition of a mitochondrial protein, a new therapeutic target for cholestatic liver...

The presence of this protein slows down the activity of the mitochondria, decreasing their ability to eliminate toxic substances such as certain bile acids. ...

2021/04/23

Large-scale genetic study sheds light on the causes of hemorrhoids (piles)

Hemorrhoidal disease (commonly referred to as hemorrhoids) affects a large portion of the population, for reasons that are mostly unknown. New research from an interna...

2021/04/22

The Spanish Royal Society of Chemistry awards the Young Researcher Prize 2021 to...

Both scientists have been awarded in the "Group Leader" category, achieving for BRTA centers two of the four prizes awarded in this category. (Vitori...

2021/04/15

BIOLAN y CIC bioGUNE desarrollarán conjuntamente un test ELISA para la detección...

Esta actuación de colaboración se enmarca en un acuerdo más amplio alcanzado entre CIC bioGUNE y BIOLAN en áreas encaminadas al diagnóstico de enfermedades y otra...

2021/03/12

A computational guide to lead cells down desired differentiation paths

A novel computer-guided design tool predicts combinations of transcription factors for more effective engineering of cell types with potential use in cell therapies an...

2021/03/11

The Abrescia Lab has recently published two new book-chapters on virus evolution...

VOLUME 1 – The Virus as a Concept – Fundamentals of Virology

2021/03/02

Alterations in serum magnesium levels are presented as a new risk factor in liver...

Liver disease patients presented altered serum magnesium levels and significantly elevated expression of the CNNM4 protein, a modulator of this cation in the liver.

2021/02/23

CIC bioGUNE researchers develop a protein capable of catalysing a chemical reaction...

The work, published in the journal Nature Chemistry, describes a zinc-binding protein which accelerates the reaction rate to levels higher than those of natural enzyme...

2021/02/16

A new method to find modulators of the immune response to COVID-19

The recent paper, published in Science Advances by the Computational Biology Laboratory at CICbioGUNE, member of the Basque Research & Technology Alliance BRTA and...

2021/02/10

Nuestras científicas para Día Internacional de la Mujer y la Niña en la Ciencia

El 11 de febrero de cada año, se celebra el Día Internacional de la Mujer y la Niña en la Ciencia proclamado por la ONU en el año 2015. El objetivo princi...

2021/02/01

Genome Analysis Platform at CIC BIOGUNE, 10x Genomics and Bonsai Lab are Sponsoring...

We are pleased to announce the 10x Genomics Single Cell Grant Program. This award offers important discounts on 10x Genomics reagents, library preparation, and bioinformatics ...

2020/12/01

9 PhD Open Positions “la Caixa” Doctoral INPhINIT Incoming Fellowship Programme...

The doctoral fellowship programme INPhINIT “la Caixa” 2021 is devoted to attracting talented Early-Stage Researchers—of any nationality—who w...

2020/12/01

Iskander Aurrekoetxea will defend his PhD Thesis this Thursday, December 3rd

Iskander Aurrekoetxea will defend his PhD Thesis entitled “Pharmacological ...

2020/11/24

17th Meeting of the Spanish Society for Developmental Biology

For the 18th to the 20th of November 2020, the “17th Meeting of the Spanish Society for Developmental Biology” took place in virtual format, orga...

2020/11/18

Sandra García Martínez will defend her PhD Thesis November 20th

Sandra García Martínez will defend her PhD Thesis entitled “Estudio de la uroporfirina I como alternativa terapéutica frente a las encefalopatías es...

2020/11/18

Leire Arreal López will defend her PhD on November 23rd

Leire Arreal López will defend her PhD Thesis entitled “Characterization of the biological and molecular activity of PML in breast cancer” next ...

2020/11/04

La Diputación Foral de Bizkaia declara como actividades prioritarias a efectos de...

El desarrollo y validación de tests serológicos escalables para la identificación de individuos seropositivos frente a la COVID-19 y el desarrollo de herramientas p...

2020/11/03

CIC bioGUNE conducts an in-depth study of the mechanism of action of Men A vaccines...

The article, published in the journal of the United States Academy of Sciences, has succeeded in deducing the minimal polysaccharide fragment (epitope) that effectivel...

2020/10/21

Los pacientes con obesidad e hígado graso con inflamación presentan un mayor riesgo...

En estos pacientes se identifica una expresión significativamente elevada de ACE2, el receptor celular del SARS-CoV-2, y de Tmprss2, la proteasa que favorece la unió...

2020/10/13

35 aniversario del Parque Científico y Tecnológico de Bizkaia

El Parque Científico y Tecnológico de Bizkaia cumple 35 años como referente de innovación y atracción de talento. Forma parte de la Red de Parques Tecnológicos de Euskad...

2020/10/08

Carrera contra el Cáncer de Mama 2020

El pasado 29 de septiembre ACAMBI presentó en Bilbao lo que este año será una carrera diferente, porqu...

2020/10/01

Charles Williams will defend his PhD thesis on October 7th

Charles Williams will defend his PhD thesis entitled “Glycoengineering of Extracellular Vesicles” next Wednesday, October 7th,  at 12.00 am....

2020/09/30

Carlos López Robles will defend his PhD Thesis on October 2th

Carlos López Robles will defend his PhD Thesis entitled “Mechanism for escpe-1-mediated membrane remodelling and cargo selection in endosomal sorting

2020/09/17

The structures of the glycan chains of the receptor binding domain (RBD) of the SARS-CoV-2...

The structures of the glycan chains of the receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein expressed in human HEK293F cells have been disentangled by NMR. M...

2020/09/08

Ezequiel Gonzalez Miranda will defend his PhD Thesis on September 11th

Ezequiel Gonzalez Miranda will defend his PhD Thesis entitled “Adaptación de u...

2020/08/13

CIC bioGUNE research reveals that a high accumulation of porphyrins is a relevant...

The article, published in the British Journal of Haematology, confirms that correcting these values may alleviate some of the symptoms of more critically ill patients....

2020/07/27

Immacolata Giordano will defend her PhD Thesis on July 28th

Immacolata Giordano will defend her PhD Thesis entitled “Proteostasis and Rare Diseases: Congenital Erythropoietic Porphyria and Townes-Brocks Synd...

2020/07/09

Parastoo Shahrouzi will defend her PhD Thesis on July 13th

Parastoo Shahrouzi will defend her PhD Thesis entitled “Genomic and functional regulation of TRIB1 contributes to prostate cancer pathogenesis” o...

2020/07/07

Research by CIC bioGUNE identifies GalNAC-MCJ as a promising therapeutic agent for...

Preclinical studies have been conducted in fatty liver toxicity models with GalNAC molecules, designed by Alnylam Pharmaceuticals, targeting the mitochondrial respirat...

2020/07/06

Ana Loizaga Iriarte will defend her PhD Thesis on July 7th

Ana Loizaga Iriarte will defend her PhD Thesis entitled “Diseño y explotación de un circuito de investigación traslacional en cáncer de próstata

2020/07/01

On the mechanism of glycosidic bond formation

The mechanism of a key chemical reaction: the formation of the glycosidic linkage of glycans has been disentangled using a variety of chemical, NMR, kinetic and theoretical me...

2020/06/30

CIC bioGUNE research opens up avenues for treating a highly aggressive cancer of...

The study identifies a protein (HuR/ELAVL1) as key for the growth and metastasis of malignant peripheral nerve sheath tumours. The findings indicate ...

2020/06/29

Scientific Response to the Coronavirus Crisis in Spain: Collaboration and Multidisciplinarity

CIC bioGUNE scientists have published an article on the response of the Chemical Biology scientific community of Spain to the COVID-19 pandemic. The letter provides an overvi...

2020/06/24

Researchers from Spain and France join forces to develop new therapies against two...

PROTEOBLOOD, a French-Spanish cooperative network for the analysis of proteinopathies and the development of individualized therapies in hematological cancers, begins ...

2020/06/22

Ilaria Calloni will defend her PhD Thesis on June 29th

Ilaria Calloni will defend her PhD Thesis entitled “NMR studies of the interactions of glycan antigens with monoclonal antibodies” on June 29th a...

2020/06/22

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing...

Townes-Brocks Syndrome (TBS) is caused by dominant mutations in the gene SALL1, leading to a broad spectrum of symptoms including frequent renal and heart impairment. Recent w...

2020/06/19

Center's de-escalation plan

This image shows the processes and actions that CIC bioGUNE undertook during the past three months to keep the essential maintenance proced...

2020/06/16

Marta Palomo will defend her PhD Thesis on June 24th

Marta Palomo will defend her PhD Thesis entitled “Gene Regulatory network in Schwann cell Disorders” on June 24th at 1...

2020/06/16

Blood vessels development depends on the maturation state of the pericytes that enclose...

The correct formation and architecture of vessels is essential in our organism. Alterations in vessel function are at the core of a variety of diseases.

2020/06/15

Opposing roles for the two main types of estrogen in obesity-driven mammary inflammation...

CIC bioGUNE researchers have participated in a collaborative study to explore the role of different types of the female hormone estrogen in...

2020/06/10

CIC bioGUNE lamenta el fallecimiento del Dr. Luis Parada

El Dr. Luis Parada fue Investigador Principal del Laboratorio 3 de la Unidad de Biología Celular y Células Madre durante 5 años (2005-2010)....

2020/06/02

CIC bioGUNE and Atlas Molecular Pharma discuss new therapeutic strategies against...

A CIC bioGUNE project, in which the Basque biotech company

2020/05/27

BIOLAN and CIC bioGUNE are working together to launch a new serological test for...

Science, Technology and Industry from the Basque Country to respond to the priority imposed by the pandemic: The initiative is part of a broader collaboration agreemen...

2020/05/08

Synthesis and Structural Analysis of Aspergillus fumigatus Galactosaminogalactans...

CIC bioGUNE researchers have participated in a joint effort to synthesize and characterize the three-dimensional structure of galactosamino...

2020/05/08

“Expression of Interest” For Hosting Marie Skłodowska Curie Actions Individual...

CIC bioGUNE, member of Basque Resear...

2020/04/23

CIC bioGUNE researchers have participated in a collective international effort to...

The existence of a new 1,2-anhydro sugar intermediate in glycoside hydrolysis has been deduced by a combination of methodologies, including organic synthesis, QM/MM calculatio...

2020/04/06

CIC bioGUNE is committing different human and material resources to the development...

The first of these aims to validate and develop fast viral diagnostic techniques for SARS-CoV-2. Diagnostic techniques would be industrially scalable and appl...

2020/03/27

A novel experimental model for the study of metastatic prostate cancer

A combination of genes alterations leads to the development of lethal metastatic prostate cancer have been identified in the study. The study provide...

2020/03/25

Decoding Intercellular Communication via Hepatocyte-Secreted Extracellular Vesicles

Extracellular vesicles (EVs) play an important role in mediating cell-to-cell communication and have received significant interest from scientists studying diverse disease con...

2020/03/23

Dr Maria Vivanco and her team at CIC bioGUNE have participated in an international...

Dr Maria Vivanco and her team at CIC

2020/03/12

EMBO Practical Course on Techniques for mammary Gland Research

Last week (1-6 March 2020), the 3rd EMBO Practical Course on Techniques for mammary Gland Research took place at EMBL, in Heidelberg, Germany. As in previous...

2020/03/03

Research by CIC bioGUNE proposes enzyme silencing as a new therapeutic approach for...

The study, published in the journal Cell Metabolism, reveals that hepatic glutaminase (GLS1) is augmented in non-alcoholic fatty liver disease. Led b...

2020/02/27

Constituido el primer Grupo Español para el Estudios de las Porfirias (GEEP)

Especialistas en Medicina Interna, Hepatología, Dermatología, Bioquímica, Pediatría, Genética y Urgencias han constituido el primer Grupo Español para el Estudio...

2020/02/25

CIC bioGUNE researchers decipher the molecular mechanism of a key enzyme in gut microbiota

The findings, published in the journal Nature Communications, will contribute to the development and design of enzymes exhibiting characteristics of biotechnological i...

2020/02/25

UbiCODE Meeting SYMPOSIUM Writing and Editing the Ubiquitin Code UBIRed Meeting

From the 24th to the 27th of February, there will take place in Bilbao three scientific events related to the biomedical res...

2020/02/24

CIC bioGUNE researchers identify new molecular mechanisms involved in the regulation...

(Bilbao, 24 February 2020). Researchers at CIC bio...

2020/02/03

ARQUIMEA Group se incorpora al accionariado de ATLAS Molecular Pharma con una participación...

ATLAS Molecular Pharma, “spin-off” de CIC bio

2020/01/28

Isaac Santos will defend his PhD thesis on February 10

Isaac Santos will defend his PhD thesis entitled “Structural determination of lip...

2020/01/23

3rd edition of the Glycobasque meeting

March 12-13 CIC bioGUNE and CIC biomaGUNE are proud of announcing the 3rd edition of th...

2020/01/17

Researchers discover the resistance mechanisms of dogs to prion diseases

This resistance could be the result of an evolutionary adaptation to carrion consumption. The research provides clues to determining new therapeutic...

2020/01/07

Jorge Simón will defend his PhD thesis on January 24th

Jorge Simón will defend his PhD thesis entitled “Targeting metabolism for resolving Non-Alcoholic Steatohepatitis” on J

2019/12/12

El investigador de CIC bioGUNE Ashwin Woodhoo obtiene cerca de dos millones de euros...

Logra el único proyecto ERC Consolidator concedido a investigadores de Euskadi en la convocatoria 2019 y el primero para la temática “neurociencias y enfermeda...

2019/12/11

Amaia Gonzalez Magaña will defend her PhD thesis on December 19th

Amaia Gonzalez Magaña will defend her PhD thesis entitled “Molecular recognition between PCNA and proteins involved in DNA replication and repair: p15 ...

2019/12/11

Marc Clos-Garcia will defend his PhD thesis on December 19th

Marc Clos-Garcia will defend his PhD thesis entitled “Multi-omics Integration for Biomarker Discovery” on December 19th. The eve...

2019/11/27

CIC bioGUNE organiza la Reunión anual del Grupo Español de Hipoxia y RedHYPOX (SAF2017-90794-REDT),...

Durante 2 días (Nov. 28 y 29), los participantes, pertenecientes a un amplio conjunto de instituciones (entre otras

2019/11/25

A team from CIC bioGUNE identifies an epigenetic therapy for the treatment of fatty...

CIC bioGUNE has patented the therapy and has reached an agreement with the U.S. biotech company Mitothera...

2019/11/19

ATLAS Molecular Pharma, galardonada con el premio “Bizkaia Sarean” a la innovación

La empresa biotecnológica ha sido premiada por la Asociación empresarial Bizkaired por su tratamiento para la porfiria eritropoyética congénita. ...

2019/11/15

9 PhD Open Positions “la Caixa” Doctoral INPhINIT Incoming Fellowship Programme...

The doctoral fellowship programme INPhINIT “la Caixa” 2020 is devoted to attracting talented Early-Stage Researchers—of any nationality—who w...

2019/11/11

CIC bioGUNE researchers unravel the three-dimensional structure of the African swine...

This breakthrough is the prerequisite not only for understanding the virus assembly but also for controlling and ultimately eliminating it. The Afric...

2019/11/05

La Real Sociedad Española de Química y Elsevier premian al joven investigador Iñaki...

El objetivo de este premio es reconocer y recompensar a los jóvenes talentos de la investigación por su significativa contribución al sector, y apoya...

2019/11/05

Antonio Del Sol Mesa, head of the Computational Biology group, receives the Outstanding...

Each year, the National Research Funds (FNR) presents awards in four categories highlighting both outstanding researchers and institutions, and promoting science-related activ...

2019/10/29

Teresa Martín-Mateos will defend her PhD thesis on November 27th

Teresa Martín-Mateos will defend her PhD thesis entitled “Characterization of USP11 as a novel r...

2019/10/21

CIC bioGUNE, CIBERER, Plataforma Malalties Minoritàries, Institut Catalá de la...

Los medicamentos huérfanos son aquellos destinados a las enfermedades raras y que, tradicionalmente no han despertado el interés de la industria farmacéutica.

2019/10/17

CIC bioGUNE inaugura un nuevo sistema de espectrometría de masas que incrementa...

El nuevo sistema timsTOF Pro de la firma Bruker pone a disposición de la comunidad investigadora una capacidad de análisis proteómicos sin precedentes.

2019/10/17

New study links the metabolic regulator PGC1A to the control of prostate cancer cell...

Cancer cells exploit a plethora of molecular pathways to prevail and dominate in the face of a hostile environment. Metabolism is one such process that cancer cells will tune ...

2019/10/16

The Introductory Week at CIC bioGUNE

PhD candidates familiarize with the research environment of the centre and get to know each other. From September 30th until October 4th CIC

2019/10/10

Workshop ‘Desde la formación al liderazgo’

ASEICA reúne en Bilbao a mujeres líderes en ciencia, cáncer y comunicación para visibilizar el talento femenino. Sólo dos de cada diez pu...

2019/10/10

Breaking the limits of the application of NMR in glycan recognition: intact glycoproteins

CIC bioGUNE scientists have developed a novel NMR-based glycoprofile analysis of an intact glycoprotein under physiological conditions that...

2019/10/10

CIC bioGUNE hosts the first women and leadership workshop organized by the Spanish...

Women are a majority in biomedical sciences-related careers. However, their presence in the different stages of the research path presents a pyramidal pattern. While the prese...

2019/10/02

ASEICA presenta en Bilbao las claves para potenciar el liderazgo femenino en ciencia...

Workshop ‘Desde la formación al liderazgo’ Bilbao, 2 de octubre de 2019.- Sólo dos de cada diez puestos de alta responsabilid...

2019/09/26

JORNADA: Designación, Desarrollo y Acceso de medicamentos huérfanos

21 de Octubre de 2019 Los llamados medicamentos “huérfanos” están destinados a tratar enfermedades que, por su rareza no ...

2019/09/25

Iratxe Macías will defend her PhD thesis on November 15th

Iratxe Macías will defend her PhD thesis entitled “Molecular basis of type I tyrosianemia. Chemical modulators of fumarylacetoacetate hydrolase as potential therapeutic...

2019/09/16

Network in Physical Virology

On November, the 13th, 14th and 15th  2019, the CIC bioGUNE (Bilbao; Spain) will host the meeting of the Span...

2019/09/11

Paula Giménez will defend her PhD thesis on September 19th

Paula Giménez will defend her PhD thesis entitled “Bases estructurales del transporte de Mg2+ mediado por los factores homeostáticos CNNM2 y CNNM4 y de su interacción...

2019/09/10

Towards a novel synthetic Streptococcus pneumoniae vaccine

In a multidisciplinary collaborative work between the Leiden Institute of Chemistry (The Netherlands), the Amsterdam Infection and Immunity Institute (Amsterdam), the Finlay V...

2019/09/04

Researchers at CIC bioGUNE identify biomarkers useful for fibromyalgia diagnosis

The research paper, published in the journal EBioMedicine, reveals a low proportion of certain bacteria in gut microbiome in fibromyalgia patients. (...

2019/07/30

Avanzan en la predicción del destino celular para comprender mejor los defectos...

La investigación, publicada en la revista Nature, ha sido llevada a cabo por grupos de investigación del Luxembou...

2019/06/27

CIC bioGUNE se sitúa entre los 100 mejores centros de investigación en biomedicina...

El ranking se basa en la cantidad y calidad de las publicaciones de los centros así como en el prestigio de los autores (Bilbao, 27 de junio 2019). CIC bio...

2019/06/19

CIC bioGUNE y la AECC de Bizkaia continúan su fructífera relación con la firma...

Mantienen desde hace ocho años una alianza estratégica con el fin de impulsar la investigación, divulgación e interacción entre los diferentes sectores relacionado...

2019/06/18

Arkaitz Carracedo obtiene el XIV Premio Fundación Banco Sabadell a la Investigación...

El jurado reconoce su innovadora contribución en el campo de la oncología y sus pioneras aportaciones para entender la progresión del cáncer de próstata. El ...

2019/05/23

El ‘big data’ llevará a superar los retos de la salud personal y la financiera

El análisis de grandes volúmenes de datos, el big data , debe llevar a la sociedad a solventar problemas tanto de índole física

2019/05/23

El CIC bioGUNE, la colaboración como piedra angular para la medicina de precisión

La Obra Social ”la Caixa” apoya la investigación del CIC bioGUNE con ayudas que van desde los programas de d...

2019/05/21

Asís Palazón, investigador de CIC bioGUNE, recibe la prestigiosa Beca FERO para...

La Fundación FERO de Investigación Oncológica entrega su beca en investigación oncológica traslacional con el objetivo de promover a jóvenes investigadores en el campo d...

2019/05/13

Bermeo Tuna World Capital impulsa una campaña solidaria para la Investigación en...

• La campaña #Bermeotunacontraelcáncer, cuyos ejes son la solidaridad y la investigación, tendrá un protagonismo especial en la Arrain Azoka de Bermeo.

2019/04/29

Un trabajo colaborativo del CIBEREHD premiado por la asociación americana de pacientes...

El trabajo de investigación titulado “Role of methylation-controlled J-protein, endogenous repressor of the mitochondrial respiratory chain, in cholestatic liver diseas...

2019/04/17

“Expression of Interest” For Hosting Marie Skłodowska Curie Actions - Individual...

CIC bioGUNE is a key research center within the national and international scie...

2019/04/08

CIC bioGUNE researchers decode new extremophile viruses whose assembly is related...

The researchers have studied two viruses which live in salt lakes and have an extraordinary survival capacity, and are crucial in understanding some of the viruses of today. ...

2019/04/02

Ana Carreras will defend her PhD thesis on April 12th

Ana Carreras will defend her PhD thesis entitled “Surface receptors that mediate the interaction of Borrelia burgdorferi with macrophages: Death and Inflammation”...

2019/04/01

Dos proyectos de CIC bioGUNE y CIC biomaGUNE reciben Ayudas a Equipos de Investigación...

El proyecto de CIC bioGUNE seleccionado buscará un tratamiento eficaz para la enfermedad del hígado graso –un trastorno potencialmente ...

2019/03/25

CIC biomaGUNE y CIC bioGUNE certifican sus Sistemas de Gestión de la I+D+i

Ambos centros han superado los requisitos de la certificación del Sistema de I+D+i conforme la Norma UNE 166002:2014, emitido por SGS ICS Ibérica, S.A. Este ...

2019/03/22

Glycobasque II is a joint event organized by CIC bioGUNE and CIC biomaGUNE

Glycobasque II is a joint event organized by CIC bioGUNE and CIC biomaGUNE that gathers the different r...

2019/03/12

Jornada sobre medicina de precisión organizada por CIC bioGUNE, CIC biomaGUNE y...

Se han analizado los estudios poblacionales y el big data en medicina de precisión. Bajo el título “Medicina de precisión: medicina por tallas”...

2019/03/11

PROTEOSTASIS - European network to integrate research on intracellular proteolysis...

The COST Action PROTEOSTASIS (http://cost-proteostasis.eu/), chaired and coordinated by

2019/03/08

Helena Coelho will defend her PhD thesis on March 25th

Helena Coelho will defend her PhD thesis entitled “NMR and Molecular Recognition of Compounds Related to the Immune System” on March 25th. The event will take pla...

2019/03/07

TUBEs, SUBES and beyond: Molecular traps for the study of proteins modified by Ubiquitin...

Post-translational protein modifications by members of the Ubiquitin family has become an intense area of research as it is implicated in many biological processes and disease...

2019/03/07

CIC bioGUNE, CIC biomaGUNE y British Council organizan una jornada sobre medicina...

En el acto se analizarán los estudios poblacionales y el big data en medicina de precisión. Bajo el título “Medicina de precisión: medicina por tallas”...

2019/03/04

Proyecto GLYCOVAX

GLYCOVAX es una red para la formación avanzada de científicos jóvenes en el diseño racional de ...

2019/02/27

Precision Medicine. "Sized medicine"

The workshop entitled "Precision Medicine. Sized medicine", co-organized by CiC bioGUNE and the British Council, ...

2019/02/25

Mondragón and Bergara supports research in prostate cancer at CIC bioGUNE

Representatives from organized groups in Mondragón and Bergara have reached out to CIC bioGUNE research group led by

2019/02/14

Extracellular Vesicles in Biomedicine

Exosomes Laboratory will participate in a new edition of the UIMP course “Extracellular Vesicles i...

2019/02/11

International Day of Women and Girls in Science

The Carracedo lab in CIC bioGUNE, committed with the dissemination of science in the International day of women and girls in science. Today, February 11th, and for the coming...

2019/01/28

Laura Bozal will defend her PhD thesis on February 1st

Laura Bozal will defend her PhD thesis entitled ”The role of primary cilia in Townes‐Brocks Syndrome” The event will take place at UPV/EHU- Salón de Grados, Facultad de...

2019/01/23

ATLAS Molecular Pharma, galardonada en los “Go Health Awards 2019” por su tratamiento...

Más de 650 proyectos nacionales e internacionales han presentado su candidatura. Las iniciativas ganadoras destacan por su carácter innovador y capacidad para mejorar la ca...

2019/01/18

A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast...

New research about the signals controlling normal and cancer stem cells in the human breast has been published in Oncogene (Nature Publishing Group), a leadin...

2019/01/17

Exosomes: toward single-particle analysis of the cellular “Deliveroo” system...

The Exosome Laboratory of CIC bioGUNE, led by Dr. Juan Manuel Falcón, has published two articles in the journal Nanoscale...

2019/01/16

El doctor Asís Palazón se incorpora a CIC bioGUNE como investigador Ikerbasque...

Liderará el laboratorio de Inmuno-Oncología, primer grupo de investigación exclusivamente centrado en inmunología e inmunoterapia del cáncer en Euskadi. De...

2019/01/15

Jornadas de Virología

Los virus dominan nuestra biosfera, siendo las entidades más abundantes. Mientras que algunos son patógenos para el ser humano, los animales y las plantas; otros son...

2019/01/10

12 PhD Open Positions “La Caixa” INPhINIT Incoming Fellowship Programme

The doctoral fellowship programme INPhINIT “la Caixa” is devoted to attracting talented Early-Stage Researchers—of any nationality—who wish to pursue ...

2019/01/04

Describen el comportamiento de la proteína quinasa LKB1, uno de los principales...

Los niveles de expresión de esta proteína se ven aumentados preferentemente en aquellos pacientes con una progresión rápida de la patología. La invest...

2018/12/20

CIC bioGUNE sponsors and hosts a meeting of national leaders in prostate cancer research

CIC bioGUNE sponsors and hosts a meeting of national leaders in prostate cancer research to support the development of strategic collaborat...

2018/12/14

Investigadores del CIC bioGUNE proponen nuevas rutas para comprender el funcionamiento...

El hallazgo, publicado en “Proceedings of the National Academy of Sciences”, demuestra que la eficiencia de una reacción enzimática se ve afectada en gra...

2018/12/11

UBIRed: Spanish Network of Excellence with participation of CIC bioGUNE

The 1st Meeting of the Spanish Network of Excellence UBIRed took place in the Center of Molecular Biology Severa Ochoca (CSIC-UAM, Madrid) on December 5th. The objective of ...

2018/12/03

Estíbaliz Orue-Etxebarria will defend her PhD thesis on December 20th

Estíbaliz Orue-Etxebarria will defend her PhD thesis entitled “Characterization of Wnt signaling in tamoxifen resistant breast cancer stem/progenitor cells” on December 2...

2018/12/03

Miguel Romano will defend his PhD thesis on December 10th

Miguel Romano will defend his PhD thesis entitled ”Mecanismos de reconocimiento y control de tráfico endosomal por el complejo retrómero” on December 10th. The event wil...

2018/11/30

CIC bioGUNE lidera la Red Temática de Excelencia de Investigación en Hipoxia

RedHYPOX es una iniciativa de diez grupos de investigación, especializados en los mecanismos que median las respuestas a hipoxia y su relevancia en situaciones fisiol�...

2018/11/29

El investigador de CIC bioGUNE Arkaitz Carracedo logra financiación de la Comisión...

El programa ERC Consolidator otorga 2 millones de euros para la ejecución de ideas transformadoras. El profesor de investigación Ikerbasque Arkaitz Carracedo,...

2018/11/26

CIC bioGUNE and CIC biomaGUNE facilities, recognised as Singular Scientific and Technical...

The Nuclear Magnetic Resonance (NMR) laboratory of CIC bioGUNE, in Derio, has been included in this infrastructure map which is upda...

2018/11/22

Gobierno Vasco reconoce la labor desarrollada por los investigadores Óscar Millet...

Se ha reconocido el trabajo realizado en excelencia, la especialización y la cercanía al mercado. La investigación desarrollada por el equipo del

2018/11/16

La Real Sociedad Española de Química concede su Medalla de Oro a Jesús Jiménez...

Alberto Fernández Tejada ha sido reconocido con el premio a Joven Investigador La Real Sociedad Española de Química (RSEQ) ha reconocido hoy a Jesús Jiménez ...

2018/11/09

La empresa vasca OWL Metabolomics, spin-off de CIC bioGUNE, está especializada en...

SYNLAB y OWL Metabolomics firman un acuerdo estratégico para la comercialización en España del Test OWLiver, el único test no invasivo para el diagnóstico de híg...

2018/10/30

CIC bioGUNE y Deusto firman un convenio para potenciar el trabajo docente e investigador...

La Universidad se une al centro de investigación biomédica para el desarrollo de ciencia de alto nivel internacional CIC

2018/10/29

Virginia Murillo will defend her PhD thesis on November 30th

Virginia Murillo will defend her PhD thesis entitled “The Role of the Wnt Receptor Frizzled-8 in Prostate Cancer Pathogenesis” on November 30th. The event will take place ...

2018/10/18

Más de 100 estudiantes para combatir la brecha de género en el campo de las ciencias...

El Parque Científico y Tecnológico de Bizkaia ha reunido hoy a más de ...

2018/10/17

Jorge Moreno Charco will defend his PhD thesis on October 29th

Jorge Moreno Charco will defend his PhD thesis entitled “Desarrollo de un nuevo sistema de cribado masivo basado en la propagación in vitro de priones recombinantes infecci...

2018/10/17

Pedro Urquiza will defend his PhD thesis on October 19th

Pedro Urquiza will defend his PhD thesis entitled “Repurposing Ciclopirox as a pharmacological chaperone active against Congenital Erythropoietic Porphyria” on October 19t...

2018/10/17

CIC bioGUNE and CIC biomaGUNE organise a seminar on the social value of science

The event was held today in Bilbao under the title “Social value of science: from knowledge to business”.Participants included Iosu Madariaga, Director of Technol...

2018/10/16

Prof. Stephen Buchwald, from MIT, will be delivering a special lecture

Prof. Stephen Buchwald, from MIT, will be delivering a lecture at UPV/EHU (Campus Leioa) Next Monday Oct 22nd. He received the 2014 BBVA Foundation Frontiers ...

2018/10/09

Bilbao acoge el tercer congreso internacional de metabolismo y cáncer

Bilbao acoge desde hoy la tercera conferencia internacional sobre avances en la investigación del cáncer. El objetivo de estas reuniones es comunicar los avances en la compr...

2018/09/27

Richard Henderson, premio Nobel de Química 2017, participa en el análisis de la...

Richard Henderson (Edimburgo, Reino Unido, 1945), premio Nobel de Química de 2017 por su investigación sobre la microscopia crioelectrónica para la determinación de la est...

2018/09/20

Un medicamento desarrollado por CIC bioGUNE y ATLAS Molecular Pharma, en la revista...

La terapia está basada en el uso de chaperonas farmacológicas, moléculas que se unen a la proteína defectuosa corrigiendo su problema de estabilidad y permitiendo su funci...

2018/09/19

CIC bioGUNE acoge un congreso internacional sobre el agente causal de la tuberculosis

(Bilbao, 18 de septiembre de 2018) CIC bioGUNE acoge hasta mañana 19 de septiembre el Congreso Internacional BILBO TB,  centrado en el estudio de la ba...

2018/09/12

Un científico vasco, ganador en los IV Premios Jóvenes Investigadores de la Fundación...

• El Dr. Arkaitz Carracedo recibirá una beca por valor de 20.000 euros para continuar con su investigación en el tratamiento del cáncer de mama en el Cen...

2018/09/10

Miguel Zamora will defend his PhD thesis on September 14th

Miguel Zamora will defend his PhD thesis entitled “Determinación estructural del virión del Virus del mosaico de la sandía por crio-microscopía electrónica” on Septem...

2018/07/25

La Fundación Bancaria ”la Caixa” presenta 20 proyectos clave para la investigación...

• La Fundación Bancaria ”la Caixa” ha presentado hoy los 20 proyectos seleccionados en la primera convocatoria abierta y competitiva de investigación biomédica puesta...

2018/06/27

Knowledge transfer from Basic Liver Research to NASH Drug Therapy Research

Galmed Pharmaceuticals recently announced that their lead NASH drug candidate, Aramchol, had achieved an FDA- regulatory-approvable endpoint demonstrating NASH resolution in t...

2018/06/20

Inauguración de los Cursos de Verano de la UPV/EHU 2018

19 Junio 2018 Palacio Miramar El pasado martes día 19 tuvo lugar la Inauguración de la XXXVII edición de los Cursos de Verano de la Universidad del País Vasco en ...

2018/06/09

Biophysicist and Nobel laureate Joachim Frank visited us this week

2018/06/05

Stavros Azinas will defend his PhD thesis on June 12th

Stavros Azinas will defend his PhD thesis entitled “Mechanical and structural studies of internal lipid-containing bacteriophage PRD1” on June 12th. The event will take pl...

2018/06/01

El cáncer óseo infantil podrá ser tratado evitando la quimioterapia intravenosa

•La Dra. María Blanco ha desarrollado nanosistemas terapéuticos, con diferentes fármacos antitumorales que pueden ser administrados por vía oral, para evitar la quimiote...

2018/05/25

TV program Lab 24 interview

2018/05/15

Researchers identify a novel link between Wnt and TGF-β signaling in cancer

A team at CIC bioGUNE, in collaboration with researchers at Turku and Åbo Akademi Universities in Finland and at Imperial College London have identified a novel link...

2018/05/15

A team of researchers from the University of Brussels, the Eindhoven University of...

Since long crystals have been essential for solving the three-dimensional structures of proteins, which is crucial for understanding the molecular mechanisms of life ...

2018/05/08

La empresa con la ciencia española

Organizaciones y patronales vinculadas a la I+D+i manifiestan su apoyo a la investigación y se suman a la petición de la Alianza de centros Severo Ochoa y unidades María de...

2018/05/02

Barcelona acogerá a más de un millar de investigadoras e investigadores en el congreso...

El Congreso de la “International Society for Extracellular Vesicles” ISEV 2018, que se celebra entre el 2 y el 6 de mayo, contará con la asistencia de profesionales de la...

2018/04/26

La Real Sociedad Española de Química concede su Medalla de Oro a Jesús Jiménez...

Alberto Fernández Tejada ha sido reconocido con el premio a Joven Investigador (Bilbao, 26 de abril de 2018). La junta de gobierno de la Real Sociedad Española de ...

2018/04/25

Conferencia sobre enfermedades neurodegenerativas a cargo de David Rubinsztein, investigador...

La charla se enmarca en el ciclo “Enfermedades Raras: con otra mirada” y se celebra este jueves 26 de abril, a las 19 horas, en el Salón de Actos del Archivo Foral de Biz...

2018/04/23

Atlas Molecular Pharma receives approval by the US Food & Drug Administration of...

April 23, 2018 DERIO, Spain.- Atlas Molecular Pharma, a private company founded in 2015 in Derio (Spain) as a spin-off from the  Centre for Co-operative ...

2018/04/20

COST Action BM1307 PROTEOSTASIS - “European network to integrate research on intracellular...

The COST Action PROTEOSTASIS BM1307, coordinated by Dr. Rosa Barrio (group leader at CIC bioGUNE) ended on the 24th of April 2018. This European network gathered 274 group mem...

2018/04/20

Final Meeting ("Proteostatic Mechanisms in Health and Disease") of the COST Action...

The COST Action BM1307 PROTEOSTASIS coordinated by Dr. Rosa Barrio (group leader at CIC bioGUNE) organized its Final Meeting- Proteostatic Mechanisms in Health and Disease- , ...

2018/04/12

Bizi Bide, the Guipuzcoan Association on Fibromyalgia organized yesterday an informative...

2018/04/10

The ERC Advanced Grant 2017 awards puts Jesús Jiménez Barbero and Luis Liz Marzán,...

The European Research Council will provide a total of EUR 4.9 million in funding over the next 5 years for the work being done by the research groups of these two Ikerbasque r...

2018/04/09

Conferencia sobre nuevas terapias para el tratamiento de enfermedades raras a cargo...

La charla se enmarca en el ciclo “Enfermedades Raras: con otra mirada” y se celebra este martes 10 de abril, a las 19 horas, en el Salón de Actos del Archivo Foral de Biz...

2018/04/09

Investigators describe the action of a protein from the bacterium that causes Lyme...

Lyme disease, or Lyme borreliosis, is an infectious disease caused by a bacterium transmitted by ticks Understanding the factors responsible for the survival ...

2018/03/27

Jornada sobre Hipomagnesemias hereditarias

14 de Abril de 2018 en el salón de actos del Hospital Miguel Servet de Zaragoza.

2018/03/19

José María Serratosa, médico jefe del servicio de Neurología del Hospital Universitario...

El doctor, referente en la especialidad de Neurología por su experiencia en epilepsia, figura en la lista Forbes de los 50 mejores médicos de España La con...

2018/03/15

CIC bioGUNE hosts The Glycovax Training Event IV (12-16, March)

GLYCOVAX is a European Training Network (ETN) funded in the framework of H2020 Marie Skłodowska- Curie ITN programme. The GLYCOVAX network aims at the education of p...

2018/03/14

Exosomes research with the participation of the Genome Analysis Platform and The...

2018/03/13

Scientists discover a novel methodology for the detection of amyloid fibers, structures...

The research, publishedin the Proceedings of the National Academy of Sciences of the USA, opens the door toward new diagnostic methods for Alzheimer’s, Parkinson’...

2018/03/13

Pablo Fernández Tussy will defend his PhD thesis on March 23rd

Pablo Fernández Tussy will defend his PhD thesis entitled "MicroRNAs in liver disease" on March 23rd. The event will take place at UPV/EHU- Salón de Grados de la ...

2018/03/05

Timothy M. Cox, director de investigación del departamento de Medicina en la Universidad...

El investigador intervendrá mañana martes en la primera jornada con la conferencia titulada “¿Qué es raro?” La conferencia, con servicio de traducció...

2018/02/15

CIC bioGUNE researchers discover a relationship between Townes-Brocks Syndrome and...

The findings, published in The American Journal of Human Genetics, support the hypothesis that aberrations in primary cilia function are contributing factors to the characteri...

2018/02/15

Reconocimiento a la labor docente de CIC bioGUNE por la Facultad de Ciencia y Tecnología...

El viernes, 22 de diciembre a las 12.00, en el Paraninfo de la Facultad de Ciencia y Tecnología de la UPV/EHU (barrio Sarriena s/n, Leioa), tuvo lugar el acto de Navidad de l...

2018/02/06

La aecc financia con 300.000€ un proyecto inter-ciberehd para combatir el cáncer...

• Está dirigido a investigar de manera multidisciplinar el colangiocarcinoma (CCA), un tipo de cáncer hepático con muy mal pronóstico. • El proyecto persigue esclarec...

2018/02/06

Vanesa Venegas will defend her PhD thesis on February 22nd

Vanesa Venegas will defend her PhD thesis entitled "Influencia de la región N-terminal de la proteína del prion en la susceptibilidad al mal plegamiento, mantenimiento de la...

2018/02/06

Montse Tersa will defend her PhD thesis on February 22nd

Montse Tersa will defend her PhD thesis entitled "Structural Basis for Substrate Recognition and Catalysis of the Mycobacterial Acyltransferase PatA" on February 22nd

2018/01/24

European Research Training Network to decipher the ubiquitin code

As of 1st of January, the ITN project UbiCODE has started ! The network is coordinated by Dr Manuel S. Rodríguez (ITAV-CNRS) and co-coordinated by Dr Rosa Barrio at CIC bioGU...

2018/01/22

Arkaitz Carracedo, galardonado con el VII Premio Nacional de Investigación en Cáncer...

(Bilbao, 22 de enero de 2018). El jurado del VII Premio Nacional de Investigación en Cáncer “Doctores Diz Pintado”, convocado por la Fundación de Investigació...

2017/12/18

A new therapy for paracetamol-induced fulminant liver damage

A team of researchers from CIC bioGUNE, CIBEREHD and the University of Vermont College of Medicine has identified the MCJ protein as a potential therapeutic target in patients...

2017/12/14

The European Medicines Agency (EMA) favorably comments on the orphan drug designation...

• Congenital erythropoietic porphyria is a rare, very serious and incurable disease. • It is a repositioned drug, which has already been tested in humans ...

2017/11/30

Lorea Valcárcel will defend her PhD thesis on December 18th

Lorea Valcárcel will defend her PhD thesis entitled 'Transcriptional control of prostate cancer metabolism' on December 18th. The event will take place at UPV/EHU-...

2017/11/29

CIC bioGUNE y OWL Metabolomics participan en un innovador proyecto de investigación...

El objetivo del proyecto LITMUS es optimizar y validar las pruebas de diagnóstico para la evaluación temprana de los pacientes con hígado graso no alcohólico e identificar...

2017/11/23

PRACTICAL WORKSHOP: Bioinformatics Tools to study exosomes ´ effects

CIC bioGUNE hosted a Practical Workshop entitled “Bioinformatics Tools to study exosomes effects” organized by the Metabolomics, Proteomics and Genome Analysis Platforms, ...

2017/11/16

Research reveals the importance of various cofactors in determining the biological...

The work advances understanding of the pathogenesis of prion strains and their ability to propagate in different tissues and hosts Furthermore, the research p...

2017/11/02

Without transfer there is no innovation and without innovation there is no future

  • This morning Alicante has started the 100xCiencia.2 meeting, which today and tomorrow brings together the vanguard of Spanish research: the Severo Ochoa and María...

2017/10/27

Arkaitz Carracedo, galardonado con el Premio “Constantes y Vitales” en la categoría...

La entrega de premios de esta campaña de responsabilidad corporativa de laSexta y Fundación AXA se ha celebrado hoy en Madrid El jurado ha valorado que Arka...

2017/10/24

Unraveling the mechanism of glycosyl transfer reactions

Glycosyltransferases (GTs) play essential roles in nature. GTs catalyze the transfer of a sugar moiety to a broad range of acceptor molecules, including mono-, oligo- and poly...

2017/10/24

Julen Tomás Cortazar will defend his PhD thesis on October 27th

Julen Tomás Cortazar will defend his PhD thesis, entitled "Identification of tick saliva antigens as vaccine candidates and immunotherapeutics", on October 27th at...

2017/10/20

CIC bioGUNE awarded by the FUNDACIÓN INOCENTE INOCENTE for the research work of...

The work of Dr. Rosa Barrio, Chair of PROTEOSTASIS, in the field of rare diseases was recognized by the Spanish foundation "FUNDACIÓN INOCENTE INOCENTE". This foundation aims...

2017/10/18

Nace la Alianza de centros y unidades de excelencia Severo Ochoa y María de Maeztu

• La Secretaria de Estado de I+D+i, Carmen Vela, ha presidido la primera reunión de la nueva Alianza de Excelencia Severo Ochoa y María de Maeztu.   ...

2017/10/10

Breaking the limits in analyzing carbohydrate recognition by NMR: Resolving Branch-Selective...

The biological recognition of complex-type N-glycans is part of many key physiological and pathological events. In fact, protein glycosylation is required for proper biologica...

2017/10/09

Más de 10.000 personas apoyan la investigación sobre cáncer de mama

Más de 10.000 personas se dieron cita el domingo 8 de octubre en la IV Carrera Solidaria contra el cáncer de mama, organizada en Bilbao por la Asociación de Cáncer de Mama...

2017/10/09

Centros de investigación europeos con experiencia en enfermedades transmitidas por...

CIC bioGUNE organiza la cuarta reunión del consorcio ANTIDotE Tratan de identificar y probar proteínas de la saliva de la garrapata que pudieran usarse como...

2017/10/09

Daniele Parisi will defend his PhD thesis on January 5th

Daniele Parisi will defend his PhD thesis entitled 'Analysis of mRNA 3' tagging pathway components' on January 5th. The event will take place at University of Liver...

2017/10/04

Un miembro del Comité Científico de CIC bioGUNE, premio Nobel de Química 2017

Richard Henderson participa en el diseño de las líneas estratégicas del centro Joachim Frank ha sido maestro del doctor en Biología Molecular, Mikel Valle...

2017/09/28

A CIC bioGUNE research team has identified a potential target for the design of antiviral...

The study has discovered a mechanism which controls the assembly of potyviruses Potyviruses constitute one of the largest groups of plant pathogens and cause ...

2017/09/26

Meeting COST Action Proteostatic Mechanisms in Health and Disease

Proteostatic Mechanisms in Health and Disease, The Final COST Action BM1307 Meeting 22-24 February 2018,  Athens,  Greece   The COST Action BM1307 PROTEOSTASI...

2017/09/25

Alicante acoge el encuentro internacional sobre transferencia y co-creación en...

• “100xCiencia.2” tendrá lugar del 2 al 3 de noviembre de 2017 en Alicante. • Acudirán destacados científicos de 40 centros y unidades de investiga...

2017/09/22

CIC bioGUNE celebra su acreditación como "Centro de Excelencia Severo Ochoa"

Félix Goñi, catedrático de la UPV/EHU, ha ofrecido una conferencia El acto ha sido clausurado por Estíbaliz Hernáez, viceconsejera de Tecnología, Innova...

2017/09/19

CIC bioGUNE recoge su acreditación como "Centro de Excelencia Severo Ochoa"

El acto de entrega del distintivo ha tenido lugar hoy en el Ministerio de Economía, Industria y Competitividad La acreditación tiene una duración de cuatro...

2017/09/19

Justyna Mleczko will defend her PhD thesis on October 19th

Justyna Mleczko will defend her PhD thesis entitled ' Study of extracellular vesicles secreted by experimental models of metabolic syndrome, and their effects on adipocytes' o...

2017/09/19

Mirian Sánchez Morán will defend her PhD thesis on October 3rd

Mirian Sánchez Morán will defend her PhD thesis entitled 'Identificación de variantes genéticas implicadas en el desarrollo de dislexia y falta de atención: Estrategias d...

2017/08/30

Natalia Comino will defend her PhD thesis on September 26th

Natalia Comino will defend her PhD thesis entitled 'Structural Basis of Glycogen Biosynthesis Regulation in Bacteria' on September 26th. The event will take place a...

2017/08/04

Giacomo Domenici will defend his PhD thesis on September 21st

Giacomo Domenici will defend his PhD thesis, entitled "Role of Sox9 transcription factor in human breast epithelial cells, breast cancer stem cells and tamoxifen resistance", ...

2017/08/02

Inspiring stories from PROTEOSTASIS COST Action or how to boost your research career...

The COST Action PROTEOSTASIS led by Dr. Rosa Barrio (CIC bioGUNE), has elaborated a video summarizing the experience of the members of the network. PROTEOSTAS...

2017/07/27

Summary of activities of the COST European Network of Extracellular Vesicles in Health...

The COST European Network of Extracellular Vesicles in Health and Disease in which CIC bioGUNE has actively participated by hosting in the Exosomes laboratory several short-te...

2017/06/29

A research team from CIC bioGUNE identifies a metabolic pathway which contributes...

Prostate cancer often exhibits molecular changes which support its growth The research unravels a mechanism through which prostate cancer produces metabolites...

2017/06/27

Georgina Ormaza will defend her PhD thesis on July 4th

Georgina Ormaza will defend her PhD thesis, entitled "Structure-function relationships of tumor suppressor", on July 4th at 11.00H. The event will take place at the...

2017/06/26

CIC bioGUNE EM community awarded with long-term programme access to Titan microscopes...

CIC bioGUNE scientists have been awarded by eBIC (Diamond Light Source, UK) with a BLOCK-ALLOCATION-GROUP (BAG) for performing high-resolution cryo-electron microscopy (cryo-E...

2017/06/14

CIC bioGUNE acoge una jornada para estudiantes sobre perspectivas de futuro tras...

Los ponentes han ofrecido su visión sobre el futuro de las carreras profesionales en la industria, la universidad y los centros de investigación Alumnos de ...

2017/06/13

Jesús Jiménez Barbero, nuevo miembro de la European Academy of Sciences (EURASC)

La Academia reconoce y elige a los mejores científicos europeos con el objeto de impulsar la ciencia en Europa   (Bilbao, 13 de junio de 2017). Jesús Jiménez ...

2017/06/01

Jesús Jiménez Barbero has been elected as Fellow of the European Academy of Sciences

Jesús Jiménez Barbero has been elected as Fellow of the European Academy of Sciences. The European Academy of Sciences (EURASC) is a non-profit non-governmental, independent...

2017/05/25

Investigadores de CIC bioGUNE revelan la complejidad estructural de la maquinaria...

Ambos trabajos, co-liderados por el investigador Ikerbasque Nicola GA Abrescia, han sido publicados en la revista Nature Communications El estudio sobre la in...

2017/05/22

Molecular mechanism of G protein activation by GIV, a protein that promotes metástasis

(Bilbao, 22 May 2017). The insufficient mechanistic information on metastasis has precluded the development of efficient therapeutics for fighting this process. However, the G...

2017/05/16

La Sociedad Química de Hungría premia a Jesús Jiménez Barbero, director científico...

Reconoce la trayectoria del científico con el premio HSC Gamboa Winkler (Bilbao, 16 de mayo de 2017). La Sociedad Química de Hungría ha galardonado a Jesús Jiménez Barbe...

2017/05/15

1st meeting of the research groups in Euskadi working in glycosciences

  The first workshop of different research groups from Euskadi working in Glycosciences, at the border between Biology and Chemistry, has taken place at CIC bioGUNE on M...

2017/05/08

Identifican que la inhibición del factor de transcripción p63 en el hígado mejora...

Investigadores de CIC bioGUNE, de la Universidad de Santiago de Compostela.  del CIBEREHD, CIBEROBN y del CIBERONC constatan que los factores de transcripción p53 y p63 ...

2017/04/06

CIC bioGUNE, acreditado como “Centro de Excelencia Severo Ochoa”

La acreditación es el mayor reconocimiento de centro de excelencia de España El proceso de evaluación se ha llevado a cabo por un comité científico inter...

2017/04/04

NEIKER y CIC bioGUNE firman un acuerdo de colaboración para realizar actividades...

Han firmado un acuerdo de colaboración para favorecer los contactos y la colaboración entre el personal investigador de ambos centros. Comparten algunas lí...

2017/03/29

Lucía Barbier will defend her PhD thesis on April 24th

Lucía Barbier will defend her PhD thesis, entitled " Targeting mitochondria and post-translation modifications: new promising approaches for the treatment of liver disease”...

2017/03/29

Imanol Zubiete will defend his PhD thesis on April 7th

Imanol Zubiete will defend his PhD thesis, entitled "Post-translational modifications in liver disease”, on April 7th at 11.00H. The event will take place at the ...

2017/03/28

Atlas Molecular Pharma recibe una ayuda del programa NEOTEC para el desarrollo empresarial

La empresa, creada por CIC bioGUNE, se encargará de desarrollar una tecnología que permita detectar moléculas que aporten estabilidad a las proteínas implicadas en el desa...

2017/03/23

Los grupos de investigación sobre exosomas en Euskadi se reúnen en CIC bioGUNE...

Estas vesículas secretadas al exterior celular son consideradas como importantes mediadores de procesos fisiológicos y biomarcadores de enfermedades El tall...

2017/03/16

CIC bioGUNE, British Council y AECC continúan con el ciclo de conferencias divulgativas...

El investigador Johan Hyllner, responsable científico de la Cell and Gene Therapy Catapult de Londres, intervendrá el próximo martes en la segunda jornada ...

2017/03/08

El consejero de Salud del Gobierno Vasco, Jon Darpón, visita las instalaciones de...

José María Mato, director general, y Jesús Jiménez, director científico, han presentado las aplicaciones de las investigaciones que lleva a cabo el centro en el ámbito d...

2017/02/23

Arkaitz Carracedo, galardonado con el premio Radio Bilbao a la Excelencia 2017 en...

El trabajo del investigador Ikerbasque en CIC bioGUNE ha sido reconocido por “seguir desentrañando los mecanismos del cáncer” (Bilbao, 23 de febrero de 2017). Arkaitz C...

2017/02/22

La metabolómica puede mejorar el diagnóstico y el tratamiento de la enfermedad...

CIC bioGUNE y OWLMetabolomics identifican dos subtipos de NAFLD El estudio, realizado en 535 pacientes con diagnóstico de NAFLD a los que se les ha determinado más de 400 l...

2017/02/15

CIC bioGUNE, British Council y AECC organizan el ciclo de conferencias divulgativas...

El investigador Bart Vanhaesebroeck, profesor del UCL Cancer Institute de Londres, intervendrá este jueves en la primera jornada Ha dedicado su carrera a des...

2017/02/10

Amelie Schober will defend her PhD thesis on February 13th

Amelie Schober will defend her PhD thesis, entitled "Establishment and characterisation of USP29 as a novel regulator of Hypoxia Inducible Factor α", on February 13th . The e...

2017/02/07

CIC bioGUNE research on nerve regeneration after injury, selected as one of the most...

The work of the Ikerbasque researcher Ashwin Woodhoo will be published in a collection of selected articles on autophagy in the Keystone Symposium 2017 Dr. Wo...

2017/02/02

Un proyecto de CIC bioGUNE sobre biomarcadores de detección del cáncer de próstata...

El Consejo Europeo de Investigación apoya con 150.000 euros la investigación para acelerar la transición entre el laboratorio y la comercialización El pro...

2017/01/25

CIC bioGUNE- CIBEREHD researchers describe for the first time the involvement of...

Liver fibrosis is an integral part in the progression of chronic liver disease, a health problem related to type 2 diabetes and obesity, the twin epidemics of the 21st century...

2017/01/20

A comprehensive biotin-based toolbox to study protein homeostasis: A community resource...

Protein homeostasis is at the heart of human wellbeing. Numerous diseases such as cancer and neurodegeneration are caused by imbalances in protein synthesis, degradation, and ...

2017/01/19

La potente mirada de una Euskadi del futuro

El pasado Julio investigadores de la Universidad de Oxford (UK), del Instituto Nacional del Cáncer - NIH (US) y CIC bioGUNE (Spain) publicaron en la revista científica Natur...

2017/01/17

Discovery of a new mechanism to understand certain interspecies prion transmission...

The article describes an alternative replicative process in which certain prion strains fail to adapt to the host The work uncovers the reasons behind the ext...

2017/01/10

CIC bioGUNE researchers uncover the molecular mechanism of PCNA protein sliding on...

The work, published in the journal Nature Communications, suggests modulator molecules of sliding as possible functional inhibitors In the long term, the rese...

2016/12/05

CIC bioGUNE researchers discover a molecular recognition mechanism which enables...

  The work, coordinated by the Ikerbasque researcher Aitor Hierro, has been published in Cell, the journal with the highest impact factor in the field of biomedicine and...

2016/11/29

Multidisciplinary Research Training Program To Uncover Cellular Control Of Immuno-Metabolism...

The EU Marie Sklodowska-Curie Innovative Training Network (ITN) “TRAIN” (“Tribbles Research and Innovation Network”) was officially launched on 12th September 2016 at ...

2016/11/22

Deporte e investigación unidos para luchar a favor de la salud masculina

  El Getxo Errugbia, en colaboración con el grupo CAYSO (Cáncer Y Sociedad), organizará el próximo sábado 26 la Movember Fest, destinada a recaudar fondos para Move...

2016/10/27

CIC bioGUNE statement on the use of research animals

CIC bioGUNE has joined the Agreement on Openness on Animal Research, pr...

2016/10/17

La marea rosa vuelve a Bilbao

Este domingo 16 de octubre se ha celebrado la 3ª Carrera solidaria contra el cáncer de mama en Bilbao organizada por la Asociación Acambi. Más de 10,000 personas se reunie...

2016/10/13

Juan Manuel Ramírez will defend his PhD thesis on October 17th

Juan Manuel Ramírez will defend his PhD thesis, entitled "In vivo strategies for the study of ubiquitination and ubiquitin-related diseases: application to Angelman syndrome�...

2016/10/06

Luca Unione will defend his PhD thesis on October 18th

Luca Unione will defend his PhD thesis, entitled "Sugars and Proteins: The Role of Dynamics in Molecular Interactions", on October 18th at 11.30H. The event will ta...

2016/10/05

Expertos internacionales se reúnen en Bilbao para discutir sobre cáncer

CIC bioGUNE organiza “Translational research in cancer cell metabolism”, un congreso sobre metabolismo y cáncer La conferencia que se celebra hasta el ...

2016/09/26

The University of the Basque Country has awarded Juan Luis García Rodríguez the...

The University of the Basque Country has awarded Juan Luis García Rodríguez the Extraordinary Doctoral Prize 2015-2016 for the thesis entitled “LKB1 in Liver Physiology”...

2016/09/22

Assembly of large, salty and fat viruses: when a bit of grease helps

  The Structural Virology group led by Nicola Abrescia attended and contributed to the 10th user’s conference of the Spanish Supercomputing Network (Red Esp...

2016/09/12

New drug discovery company in the area of rare diseases

The new company, Atlas Molecular Pharma, aims to develop a technology capable of detecting molecules which stabilize proteins involved in the development of certain rare disea...

2016/09/06

Amaia Arruabarrena will defend her PhD thesis on September 16th

Amaia Arruabarrena will defend her PhD thesis, entitled "Metabolic Alterations in Prostate Cancer Pathogenesis”, on September 16th at 12.00H. The event will take ...

2016/08/24

A new study sheds further light on vulnerabilities in aggressive breast cancer

Triple negative breast cancer is characterised by a lack of markers indicating the most effective treatment strategies A study led by the group of Dr. Arkaitz...

2016/07/19

Translational research in cancer cell metabolism conference

Cancer metabolism is a rapidly evolving research area. The main aim of this conference is to bring together can...

2016/07/05

Jesús Jiménez-Barbero has been appointed member of the Editorial Advisory Board...

Jesús Jiménez-Barbero has been appointed member of the Editorial Advisory Board of ACS Omega, a new multidisciplinary, open access and online journal that represents a new a...

2016/06/30

Announcement of the 3rd PROTEOSTASIS Action Meeting: “Proteostasis and its Biological...

About the meeting The COST Action BM1307 PROTEOSTASIS coordinated by Dr. Rosa Barrio (group leader at CIC bioGUNE) organizes the 3rd PRO...

2016/06/29

CIC bioGUNE inaugurates a Nuclear Magnetic Resonance spectrometer for the study of...

The innovative equipment has been acquired with financial support from the Department of Territorial and Economic Development of the Bizkaia Provincial G...

2016/06/24

Lucia Mayela Gayosso will defend her PhD thesis on July 5th

Lucia Mayela Gayosso will defend her PhD thesis, entitled " Desarrollo de líneas celulares competentes para la replicación de priones humanos mediante la reprogramación de ...

2016/06/21

Almudena Gerpe will defend her PhD thesis on July 6th

Almudena Gerpe will defend her PhD thesis, entitled "Estudio de la regulación de PHD1 y PHD3 por SUMO”, on July 6th at 12.00H. The event will take place at the S...

2016/06/21

La Academia de Ciencias Médicas de Bilbao nombra a Óscar Millet presidente de su...

La centenaria institución interrelaciona la sanidad con la sociedad   (Bilbao, 21 de junio de 2016). ...

2016/06/17

Field Guidelines for Genetic Experimental Designs in High-Throughput Sequencing

  About this book: High throughput sequencing (HTS) technologies have conquered the genomics and epigenomics...

2016/06/15

MALDI-Imaging Mass Spectrometry: a step forward in the anatomopathological characterization...

  Aortic stenosis (AS) is the most common form of human heart valve diseases.  Once symptoms develop, there is an inexor...

2016/06/10

CIC bioGUNE acoge una conferencia de Andrew Hessel, referente mundial en biología...

Es investigador de Autodesk Research San Francisco y co-fundador de Pink Army Cooperative, la primera cooperativa biotecnológica del mundo

2016/05/25

CIC bioGUNE researchers identify immune cell checkpoints that regulate cell responsiveness...

The research describes the role of the mitochondrial MCJ protein in the metabolism of immune cells The work, conducted in collaboration ...

2016/05/23

The metabolism of prostate cancer cells is a determining factor for the development...

The expression of a central regulator of cell metabolism, PGC1A is associated with prostate cancer aggressiveness The research paves the...

2016/05/18

Estudio molecular de exosomas, sangre y microbioma en Fibromialgia

La Fibromialgia es una enfermedad crónica que cursa con dolor intenso en numerosos puntos del cuerpo, que se estima la padece un 3% de la población y para la cual no existe ...

2016/05/16

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan...

Allergy may be combated by using Allergen immunotherapy (AIT). However, AIT displays a variety of shortcomings, related to security, efficacy, duration, and patient compliance...

2016/05/16

The mechanism of sulfur transfer across protein-protein interfaces: the CSD model...

Cellular mobilization of elemental sulfur (S) is a crucial step for the biosynthesis of several entities essential for life, including amino acids, vitamins, and modified RNA ...

2016/05/16

Our scientists develop a novel fragment-based combinatorial Nuclear Magnetic Resonance...

One of the most expensive and time-consuming tasks in the drug discovery process aims at developing selective binders from promiscuous lead compounds. A team of scientists fro...

2016/05/16

Immunological adjuvants may help to stimulate the immune response to the co-administered...

Immunological adjuvants may help to stimulate the immune response to the co-administered antigens. Therefore, they have become increasingly important for developing prophylact...

2016/04/12

CIC bioGUNE, only Spanish research centre selected in the latest call for applications...

The centre will research into the metabolism of hummingbirds, capable of storing and burning fat very rapidly The HFSPO will provide over one million euros in funds ...

2016/03/17

Patricia Zuñiga will defend her PhD thesis on April 8th

Patricia Zuñiga will defend her PhD thesis, entitled "Implicación de LKB1 en la patogénesis y progresión del cáncer de próstata”, on April 8th at 12.30H. Th...

2016/02/15

Investigadores de CIC bioGUNE participan en el 2º Encuentro Industrias Bio-Salud...

En el encuentro organizado por Basque Biocluster han intervenido la Dra. María Vivanco y el Dr. Joaquín Castilla(Bilbao, 12 de febrero de 2016). Los ...

2016/02/09

Observation at atomic resolution of an enzyme opens a pathway for inhibition of colon...

A team of scientists from CIC bioGUNE, University of Liverpool and Cedars-Sinai hospital in California, using high-resolution structures, have determined the catalyti...

2016/02/08

CIC bioGUNE y la AECC celebran el 5º aniversario de su colaboración con un...

El presente y el futuro en la investigación de cáncer de hígado y la transferencia desde el laboratorio al paciente han centrado las intervenciones ...

2016/02/04

La creación de REDiEX potenciará la medicina personalizada en España

 CIC bioGUNE participa en esta red que nace con la voluntad de potenciar las interacciones científicas La Red de Excelencia e Innovación en Exosomas a...

2016/02/01

CIC bioGUNE celebra su undécimo aniversario con una conferencia científica...

El premio Príncipe de Asturias de Investigación Científica y Técnica (2014) ha disertado sobre la transferencia de la investigación a la emp...

2016/01/13

Lucia Pirone will defend her PhD thesis on February 18^th

Lucia Pirone will defend her PhD thesis, entitled "Post-translational modifications by SUMO and ubiquitin-like proteins; role of sumoylation on SALL proteins", on Fe...

2016/01/13

The ubiquitin ligase TRAIP binds PCNA and protects the genome in response to replication...

The replication of the genetic material can be blocked or slowed down by different causes creating replication stress in the cell. This is the primary source of genome instabi...

2016/01/12

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

While current therapies have achieved modest successes in some cancers, significant problems remain with most of our approaches to treatment. In particular, many newer target...

2016/01/11

Paulina Pluta will defend her PhD thesis on February 2^nd

Paulina Pluta will defend her PhD thesis, entitled "Computational and biophysical methods for the characterization of protein-protein and protein-ligand interactions"...

2016/01/11

David Gil will defend his PhD thesis on January 11^th

David Gil will defend his PhD thesis, entitled "Automatización de la adquisición y procesamiento de datos en microscopía electrónica tridimens...

2015/12/22

Beca de investigación AECC Bizkaia

La mañana del 22 de diciembre tuvo lugar la firma de la última beca de investigación del año, concedida en esta ocasión a Mª Luz Mar...

2015/12/21

1st meeting of the Spanish Hypoxia Network (HypoxiaNet.es)

 HypoxiaNET.es is an open initiative to all researchers (basic, clinical and industrial) with a common interest in the study of cellular and molecular mechanisms that med...

2015/12/18

Highest resolution structure of a flexuous filamentous plant virus

 Flexible filamentous viruses are eukaryotic RNA viruses and economically important plant pathogens. Their viral particles contain several hundred copies of a helically a...

2015/12/09

Hasier Eraña will defend his PhD thesis on December 21^st

Hasier Eraña will defend his PhD thesis, entitled "Estudio de los determinantes moleculares que modulan la resistencia del conejo a la infección por priones...

2015/12/09

Understanding proteins that only work with a pinch of salt

 Life on earth exhibits an enormous adaptive capacity and living organisms can be found even in extreme environments. For instance, halophilic archaea thrieve in highly s...

2015/12/01

Ganeko Bernardo will defend his PhD thesis on December 15^th

Ganeko Bernardo will defend his PhD thesis, entitled "Structural characterization of helices A and B of Kv7.2 channel bound to Calmodulin. The calcium effect.", on D...

2015/11/23

A key moment for science

- The Center for Cooperative Research in Biosciences CIC bioGUNE has managed to observe empirically for the first time a chemical species with a short lifetime that is g...

2015/11/17

Evolution of SUMO function and chain formation in insects.

To understand the function and mechanisms of postranslational modification is crucial to understand protein function. Modifications by the Small Ubiquitin-like Modifie...

2015/10/30

Carrera contra el Cáncer de Mama - Bilbao 2015

El pasado domingo 25, 10.000 camisetas rosas llenaron Bilbao de color y esperanza. Acambi (Asociación de Cáncer de Mama de Bizkaia) y el Gimnasio Urtzi organizar...

2015/10/19

The CIC bioGUNE's International Scientific Board will meet to design the strategies...

- The International Scientific Advisory Board, made up of leading international researchers, will hold its tri-annual meeting in order to analyse the research centre'...

2015/10/08

The article "Insight into the Assembly of Viruses with Vertical Single β-barrel...

by Gil-CartonGil-Carton D, Jaakkola ST, Charro D, Peralta B, Castaño-Díez D, Oksanen HM, Bamford DH, Abrescia NG. Structure. 2015, 23:1866-1877. doi: 10.10...

2015/09/30

Gabriel Ortega will defend his PhD thesis on October 5^th

Gabriel Ortega will defend his PhD thesis, entitled "Structural Studies of the Hypersaline Adaptation of Proteins belonging to Halophilic Archaea", on October 5th at...

2015/09/29

BM1307 PROTEOSTASIS Meeting in collaboration with EMBO (18th to 22nd September 2015)....

 About the meeting The COST Action BM1307 PROTEOSTASIS coordinated by Dr. Rosa Barrio (leader researcher at CIC bioGUNE) organized its third meeting in parallel wit...

2015/09/16

Cellular and molecular heterogeneity in breast cancer

 Breast cancer is a very heterogeneous disease. We now know that breast tumors contain cells with properties of stem cells (cancer stem cells, CSCs) that support tumor in...

2015/09/15

The quest of anticancer vaccines: Deciphering the fine-epitope specificity of cancer-related...

The expression of MUC1, a glycoprotein displaying complex oligosaccharides, is usually increased with aberrant glycosylation in tumour cells. In fact, the carbohydrate side ch...

2015/09/03

A study shows the peripheral nervous system regeneration capacity after a lesion

- The project, led by CIC bioGUNE and University College London, has discovered a new mechanism that facilitates the regeneration of the layer that surrounds the neurons...

2015/08/31

The unexplored archaeal domain and its viruses

Archaeal viruses represents one of the most challenging and yet unknown area of investigation. Archaeal viruses live in extreme environments (alkaline, acidic conditions...

2015/08/07

A new study shows that rabbits are not resistant to infection by prions

 - A project led by CIC bioGUNE shows that rabbits are susceptible to spongiform encephalopathies, neurodegenerative diseases caused by prions.- The research, publi...

2015/08/05

BRCA1, a breast cancer predisposition gene, a potential contributor in a human and...

 Amyotrophic lateral sclerosis (ALS) is characterised by selective motoneuron degeneration in the spinal cord, brainstem and motor cortex leading to progressive muscle we...

2015/07/24

Steroids and Insulin pathways collaborate to promote tissue growth

How organisms reach their final size is a crucial question in Biology that is deeply related with the mechanisms involved in cell growth control and the pathologies asso...

2015/07/20

Discovered the potential of a DNA regulator in the treatment of liver diseases

 - Research led by CIC-BioGUNE has achieved the remission of the biliary cirrhosis phenotype by controlling the activity of an epigenetic regulator. - The research, ...

2015/07/20

Cellular Uptake and Cytotoxic Effect of Epidermal Growth Factor Receptor Targeted...

Felipe Goñi-de-Cerio, Julie Thevenot, Hugo Oliveira, Encarnación Pérez-Andrés, Edurne Berra, Marc Masa, Blanca Suárez-Merino, Sé...

2015/07/15

Mammary Stem Cells

A book has recently been published on "Mammary Stem Cells", as part of the prestigious series on Methods in Molecular Biology from Springer. The book has been edited...

2015/07/15

Chafik Harrathi will defend his PhD thesis on July 28^th

Chafik Harrathi will defend his PhD thesis, entitled "Estudio de la susceptibilidad/resistencia del ganado ovino a la infección por priones utilizando modelos de p...

2015/07/15

Molecular processes affecting mammary luminal progenitor fate

 In contrast to most mammalian organs, the mammary gland develops mostly after birth. Mammary epithelium is a bilayered structure formed by luminal and myoepithelial cell...

2015/07/15

Monitoring Glycan-Protein Interactions by NMR Spectroscopic Analysis: A Simple Chemical...

 Detection of molecular recognition processes requires robust, specific and easily implementable sensing methods, especially for screening applications related to the dru...

2015/07/14

Laura Palomo Díaz will defend her PhD thesis on July 28th

Laura Palomo Díaz will defend her PhD thesis, entitled "Metabolic implications and characterization of hepatic extracellular vesicles in drug-induced liver injury&...

2015/07/06

New pharmacological therapies for treating the most aggressive form of porphyria

- Research led by the Center for Cooperative Research in Biosciences seeks to obtain effective methods for changing the stability of the enzyme that causes development o...

2015/07/01

Prohibitins (PHBs) comprise an evolutionary conserved and ubiquitously expressed...

Prohibitins (PHBs) comprise an evolutionary conserved and ubiquitously expressed family of proteins with a variety of suggested activities in different cellular compartments. ...

2015/06/29

The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures

 The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures. This molecule is expressed in ca. 90 % of carcinomas, and there is a di...

2015/06/22

Marie Skłodowska-Curie action awarded to carry out structure-function studies...

 Bilbao, June 15th, 2015: Virologist Dr. Hani Boshra has been awarded with an Individual Fellowship Marie Skłodowska-Curie action (MSCA) to study Schmallenberg virus...

2015/06/16

Healing tears

 - CIC bioGUNE and the company Bioftalmik have been working on a project that has identified a broad catalogue of endogenous peptides in human tears, and some of them hav...

2015/06/09

The barrier preventing fatal disease transmission from deer to humans is identified

- Research by the University of California in co-operation with the Ikerbasque researcher Joaquin Castilla's team at CIC bioGUNE, gains deeper knowledge in resistanc...

2015/05/21

Human Basal Tear Peptidome Characterization by CID, HCD, and ETD Followed by in Silico...

Endogenous peptides are valuable targets in the analysis of biological processes. The tear film contains proteins and peptides released by the tear duct mucosal cells, i...

2015/05/13

A new book on the role of carbohydrates in nature, with special emphasis on their...

A new book on the role of carbohydrates in nature, with special emphasis on their roles in disease, is available. The book has been edited by J. Jiménez-Barbero, Scient...

2015/05/08

Defense of the PhD Thesis of Leire Herboso

Leire Herboso will defend her PhD thesis, entitled "El papel de los receptores SR-BI en la esteroidogénesis y de la Hormona Ecdisona en el crecimiento ", on M...

2015/05/08

The scientific director of CIC biomaGUNE, Luis Liz-Marzán, elected member...

 - Along with José María Mato and Soledad Penadés, three scientists from CIC bioGUNE and CIC biomaGUNE are now part of the scientific institution.&nb...

2015/04/21

Centros de investigación y empresas ‘bio' de Euskadi buscan estrechar...

- Los centros de investigación CIC biomaGUNE y CIC bioGUNE y el cluster de empresas ‘bio', Basque Biocluster, organizan una jornada para impulsar ámbitos d...

2015/03/30

Protein homeostasis project brings researchers together

Intracellular proteolysis is critical to maintaining cellular homeostasis, and aberrations in this process play a central role in pathologies such as cancers, immune diseases ...

2015/03/17

The oncogenic protein p15 binds and crosses the PCNA ring, suggesting a mechanism...

 PCNA forms a ring that encircles and slides on the DNA. It is an essential factor in replication and repair that recruits DNA-modifying enzymes and regulatory proteins t...

2015/03/16

Revealing the mode of binding between the DNA repair machinery and a carcinogenic...

 - A team from CIC bioGUNE led by Francisco J. Blanco has determined the structure of the complex formed by the p15 protein, present in several kinds of cancer and part o...

2015/03/04

Ramón Areces Foundation funds research on therapeutic application of exosomes

 - The study is coordinated by CIC bioGUNE researcher Juan Manuel Falcón-Pérez, an expert in exosome studies  - The Ramón Areces Foundation...

2015/02/17

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver...

 Liver Cancer, the fifth most common cancer worldwide and the third leading cause of death, is a very complex and heterogeneous pathology with multiple and distinct signa...

2015/02/16

Modulating Weak Interactions for Molecular Recognition: A Dynamic Combinatorial Analysis...

 The interactions between aromatic moieties and aliphatic entities are of paramount importance for essential molecular recognition events. In particular, CH-pi contacts a...

2015/02/12

TV3 telethon funds Alzheimer's disease study by CIC bioGUNE and CIC biomaGUNE

- The project has secured 400,000 euros in funding from the telethon that the Catalan public TV channel organises every year, and which in 2013 raised money for neurodeg...

2015/01/26

Ikerbasque researcher Jesús Jiménez Barbero is appointed new scientific...

- A CSIC Research Professor and current president of the Spanish Royal Society of Chemistry (RSEQ), he joins the centre as an Ikerbasque researcher. - Between 2009...

2015/01/26

Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase fromMycobacterium...

 Mycobacterium tuberculosis is a human pathogen that causes tuberculosis, a disease that kills ca. 2 million people worldwide every year. The occurrence of multidrug and ...

2015/01/22

Structure and interactions of a multifunctional domain of HuR protein

The human antigen R (HuR) is a powerful regulator of cancer. By binding and stabilizing certain messenger RNA molecules, it promotes the production of other proteins rel...

2015/01/14

10º aniversario del Centro de Investigación Cooperativa en Biociencias

 Una década de biociencias en Euskadi- El centro vasco es hoy una realidad dentro del panorama científico nacional e internacional como agente generad...

2014/12/23

Exosomes involved in tissue and organ formation

 - A study conducted by CIC bioGUNE, in collaboration with Severo Ochoa Molecular Biology Centre, shows that a Hedgehog protein travels through exosomes, which are small ...

2014/12/16

Nora Bengoa will defend her PhD thesis on December 18th

Nora Bengoa will defend her PhD thesis, entitled "Noncanonical Wnts and their Receptors in Neural Differentiation", on December 18th at 4 pm. The event will take pl...

2014/12/12

Elisa Aida da Silva Ferrada will defend her PhD thesis on December 22^nd

Elisa Aida da Silva Ferrada will defend her PhD thesis, entitled " Role of ubiquitin and SUMO molecules in the regulation of cellular factors", on December 22nd...

2014/12/10

One of our latest publications about Legionella appears as Scientific Highlight in...

A long-standing question in the field of microbial pathogenesis is how virulence factors are regulated within host cells and how their activity is specifically directed toward...

2014/12/09

Exosomes participate in the Hedgehog gradient formation required in development

 Tissue and organ formation require a tight concerted coordination of many different cell types that have to proliferate and differentiate in the right place and moment. ...

2014/12/02

Marta Iruarrizaga will defend her PhD thesis on December 11th

Marta Iruarrizaga will defend her PhD thesis, entitled "Control of gene expression du...

2014/11/19

Study discovers how rare disease causing cardiovascular and cognitive disorders is...

- This rare disease is homocystinuria, which affects 1 in every 250,000 children born in Spain and has recently been included in neonatal screening - A study conduc...

2014/11/18

Structure of a protein interaction key for microtubule elongation

Cell division involves the segregation of the genetic material into the daughter cells that, when not properly controlled, may produce aberrant chromosomes and lead to c...

2014/10/28

The 7th Fero Grant is awarded to a study by Arkaitz Carracedo concerning new targets...

- The CIC bioGUNE received the award from the cancer research foundation yesterday. - His project concerns a protein present in almost all the most aggressive brea...

2014/10/06

International experts in cell signalling and cancer metabolism gather at CIC bioGUNE

- From tomorrow until Thursday a congress will gather 120 scientists. - It is one of the most important European events in this field.- Its goal is to bring ...

2014/10/03

Resistir el déficit de oxígeno

 Ya lo dijo Darwin "no son las especies más fuertes las que sobreviven, ni las más inteligentes, sino aquellas que se adaptan mejor al cambio". El...

2014/10/01

The first non-invasive test to diagnose fatty liver disease is awarded two patents...

- The diagnostic test, which correctly categorises the disease in 94% of patients, is already being marketed as Owl Liver by the Basque company Owl. - The company w...

2014/09/22

Discovery of a new therapeutic target to fight against Legionella

- The bacteria releases a protein in human cells, called VipD, that facilitates its intracellular survival.- This discovery may open the door to de...

2014/09/17

El Diputado de Promoción Económica visita bioGUNE para conocer su nuevo...

- Imanol Pradales ha acudido hoy a conocer este nuevo equipamiento-

2014/09/16

Scottish Ubiquigent will sell a product developed by CIC bioGUNE and Histocell to...

 - The project is born from research projects undertaken in the CIC bioGUNE research centre on genetically modified mouse cells.  - Basque company Histocell will be ...

2014/08/12

A switch in Wnt signaling mediates early differentiation of human neural stem cells.

 A new study from the Cell Biology and Stem Cells Unit focuses on secreted proteins called Wnts, which are particularly important for tissue development and morphogenesis...

2014/07/30

US patent issued for a new CIC bioGUNE product to develop new cancer treatments

 - Tandem-repeated Ubiquitin Binding Entities (TUBEs) enable the identification of biomarkers, new therapeutic targets and drugs against different pathologies including o...

2014/07/18

Using in vivo-biotinylated ubiquitin to describe a mitotic exit ubiquitome from human...

 During mitotic cell division chromosomes need to be repackaged into daughter cells, a complicated process guided by several protein regulators, which are themselves tigh...

2014/07/08

Discovery of a protein that allows brain stem cells to generate new neurons

 - A study conducted on mice, in which CIC bioGUNE is involved, has revealed that the MTP-MMP protein 'unblocks' this type of cell- Understanding this proce...

2014/06/26

CIC bioGUNE's Animal Unit renews the accreditation that certifies the use of...

 The Animal Unit of the CIC bioGUNE has renewed its "Full Accreditation" by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC)....

2014/06/20

A possible pathway for inhibiting liver and colon cancer growth is found

 - A study by CIC bioGUNE, the University of Liverpool and the US research centre USC-UCLA has revealed the structure of a protein complex involved in these diseases

2014/06/16

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by engineering...

 Congenital erythropoietic porphyria (CEP) results from a deficiency in uroporphyrinogen III synthase enzyme (UROIIIS) activity that ultimately stems from deleterious mut...

2014/05/30

La química de carbohidratos rinde homenaje a la trayectoria científica...

- El fundador y ex-director científico de CIC biomaGUNE es una de las grandes referencias internacionales en la investigación en la química de los c...

2014/05/20

Medalla de la Real Sociedad Española de Química a la trayectoria científica...

 - Se trata del mayor reconocimiento que concede anualmente la RSEQ a la carrera científica de un investigador - "Me siento muy orgulloso de ver mi...

2014/05/07

Cultivar para recoger, la inversión en investigación para el futuro...

 La innovación es el futuro, y debe desempeñar una función cardinal en el cambio de modelo económico que nuestra sociedad necesita. Una de las...

2014/04/30

Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin

 Ubiquitination is behind most cellular processes, with ubiquitin substrates being regulated variously according to the number of covalently conjugated ubiquitin molecule...

2014/03/31

Lysine Methylation Mapping of Crenarchaeal DNA-Directed RNA Polymerases by Collision-Induced...

 Enzymatic machineries fundamental for information processing (e.g. transcription, replication, translation) in Archaea are simplified versions of their eukaryotic counte...

2014/03/26

Abnormal levels of a molecule are associated with diabetic neuropathy

 - Researchers from CIC bioGUNE have revealed that the molecule SAMe causes changes in the genome that affect the peripheral nervous system - Diabetic neuropat...

2014/03/13

S-adenosylmethionine levels regulate the Schwann cell DNA methylome

 Axonal myelination is essential for rapid saltatory impulse conduction in the nervous system, and malformation or destruction of myelin sheaths leads to motor and sensor...

2014/02/06

El investigador británico Mark Kearney
explica en Bilbao la relación...

 - El científico británico abrirá el jueves 6 de febrero (19.30 horas) la IX edición del ciclo de conferencias organizado por la Fundaci&oacut...

2014/01/31

CIC bioGUNE celebra su noveno aniversario

- El centro vasco de investigación en biociencias ha celebrado su noveno aniversario con una conferencia a cargo del investigador Óscar Marín C...

2014/01/14

Sox2 promotes tamoxifen resistance in breast cancer cells

 A study by the group of Maria Vivanco, in collaboration with the group of Robert Kypta (also at CIC bioGUNE), Dr Zabalza (Hospital of Galdakao) and Dr López-Ruiz ...

2014/01/10

European network to carry out research on protein life cycle

 - CIC bioGUNE leads the Proteostasis initiative, with more than 100 participant European laboratories.- Companies, universities and research centres from 20 countries, s...

2014/01/07

SIRT1 controls liver regeneration by regulating BA metabolism through FXR and mTOR...

 Sirtuin 1 (SIRT1) is a class III histone deacetylase that tightly controls lipogenesis, protein synthesis, gluconeogenesis, and bile acid (BA) homeostasis. Hence, SIRT1 ...

2013/12/23

Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine...

 Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in Western countries, being frequently associated with obesity, dyslipidemia and insulin resist...

2013/12/18

The Movember Foundation has renewed by second year the EXOSOMES GAP1 project

Thanks to this award CIC bioGUNE researchers in close collaboration with the Basurto Hospital and the BIOEF Foundation are studying a special type of small vesicles called exo...

2013/12/12

Rare disease that causes cardiovascular and mental disorders

3D structure of key...

 - CIC bioGUNE researchers have discovered the 3D structure of a protein (CBS), whose dysfunction causes the disease known as homocystinuria, with an international incide...

2013/12/09

What goes wrong in Angelman Syndrome? Fruit flies give us the insight

 Angelman syndrome (AS) is a severe neurodevelopmental disorder related to autism, which presents also with intellectual disability. The cause of AS is the loss of functi...

2013/11/29

Structural basis for the allosteric regulation of human cystathionine beta synthase,...

 Cystathionine β-synthase (CBS) is the key enzyme in the transsulfuration pathway controlling the flux of sulfur from methionine to cysteine, which is a precursor of...

2013/11/11

A protein that 'rebels' against breast cancer treatment

- A study headed by the researcher María Vivanco, at CIC bioGUNE, has shown that the protein SOX2 makes tumour cells insensitive to hormone therapy.- This study h...

2013/10/30

Structural virology: making an impact in biology through hybrid methods

 The study of virus structures has contributed to structure biology methodological advances that go beyond virus-specific methods and are generally applicable (molecular ...

2013/10/29

One of our groups opens the way to combatting dermatological disorders associated...

- The prestigious scientific journal PNAS has published a study from Dr. Oscar Millet's group, in collaboration with the University of Bordeaux, which shows that dru...

2013/10/17

Mechanism of Membranous Tunnelling Nanotube Formation in Viral Genome Delivery

- The laboratory of Dr. Abrescia has described for the first time how the virus PRD1 uses lipids and proteins that are part of its structure to generate a nanotube used ...

2013/10/16

CIC bioGUNE discovers a new form of virus reproduction

- The laboratory of Dr. Abrescia has described for the first time how the virus PRD1 uses lipids and proteins that are part of its structure to generate a nanotube used ...

2013/10/04

UPV/EHU awards one of our groups with the Special Doctoral Dissertation Award in...

 The Postgraduate Committee of the UPV/EHU awarded Dr. Nuria Martinez-Lopez with the Special Doctoral Dissertation Award in Health Sciences in the year 2010/2011 for her ...

2013/10/01

"Ayuda a investigación Oncológica 2013" grant awarded to...

 After studying the evaluation report by the A.N.E.P. (Agencia Nacional de Evaluación y Prospectiva), the Scientific Foundation Board of the "Asociació...

2013/09/19

The Spanish Association Against Cancer (AECC) awards one of our groups with a three...

Pablo Fernadez Tussy, from Mª Luz Martinez Chantar...

2013/09/18

Best poster presentation award in The Metabolic Regulation section of the XXXVI Congreso...

 Lucia Barbier, PhD student at the

2013/09/11

EU allocates €1.5m funding to Arkaitz Carracedo's prostate cancer research...

- The European Research Council has given the CIC bioGUNE researcher an ERC Starting Grant, aimed...

2013/09/09

Ceramide-1-phosphate trafficking regulates intracellular eicosanoic lipid levels...

 In the presence of harmful stimuli, intracellular production of eicosanoids triggers the pro-inflammatory response. However, chronic inflammation has obvious...

2013/09/03

European project searches for tick-borne disease antidote

- CIC bioGUNE is taking part in the European project ANTIDotE, which aims to find components in the arthropod's saliva that would help to prevent diseases caused by ...

2013/09/03

Structural Basis for the Interaction of the Golgi-Associated Retrograde Protein Complex...

Fusion of transport vesicles with the appropriate target compartment is a tightly regulated process for cargo delivery in the endomembrane system of all eukaryotic cells. This...

2013/07/29

Sensing low amino acids levels on the ribosome explored by cryoEM

In some bacteria the scarcity of amino acids is sensed on the ribosome, where RelA, the stringent factor, is activated by the presence of cognate and deacylated tRNA. Am...

2013/07/22

Abren un nuevo frente en la lucha contra
el cáncer de hígado

 - Una investigación del director de CIC bioGUNE, José María Mato, pone las bases para una nueva aproximación al tratamiento del cáncer...

2013/07/08

MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular...

 MAT1A is the main gene involved in the hepatic synthesis of S-adenosylmethionine (SAMe), the principal biological methyl donor and a precursor of polyamines and glutathi...

2013/06/20

Abrescia's group has recently published its new book-chapter: Combined Approaches...

Nicola Abrescia, Ikerbasque Research Professor and PI at the Structural Biology Unit at CIC bioGUNE has led the accomplishment of an exhaustive book-chapter on the hybridizati...

2013/06/14

The eBook "Bioinformatics for High Throughput Sequencing" is one of the...

 Since its online publication on Oct 25, 2011, there has been a total of 10268 chapter downloads for the book "Bioinformatics for High Throughput Sequencing" (e...

2013/06/12

Nanoparticles for controlled drug release

 - Researchers from CIC bioGUNE are participating in the study of a novel technique that allows medicines to be transported inside nanoparticles.  - Once these...

2013/05/16

Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD

The covalent attachment of adenosine monophosphate (AMP) to proteins, a process called AMPylation (adenylylation), has recently emerged as a novel theme in microbial pat...

2013/04/29

Ikerbasque y CIC bioGUNE convierten euskadi en un referente internacional en biociencias

 o Los 12 investigadores Ikerbasque en CIC bioGUNE han captado más de 3 millones de euros y han publicado más de 50 estudios. o 5 de los 12 investigado...

2013/04/24

Discovery of a gene involved in fatty liver disease

  - An international research consortium led by CIC bioGUNE has found that the gene SLC2A1 is associated with non-alcoholic fatty liver disorders, whose complete genetic ...

2013/04/22

Regulating the regulators: Steroid hormone synthesis is controlled by SUMO, Ftz-f1...

Steroid hormones are cholesterol derivates that control many aspects of animal physiology, including development, growth, energy storage and reproduction. In insects, the main...

2013/04/19

New insight into the regulation of prostate gland morphogenesis

Researchers from the Cell Biology and Stem Cells Unit at CIC bioGUNE, Imperial College London and DKFZ Heidelberg have uncovered a novel link between the tumor suppressor Dkk...

2013/04/08

Shedding light on new metabolic pathways implicated in cancer

The group of Arkaitz Carracedo at CIC bioGUNE has corresponded a review article in the prestigious journal Nature Reviews Cancer where he revisits the metabolic pathways requi...

2013/02/25

The great human protein 'encyclopaedia'

 - The Basque research centre CIC bioGUNE is participating in one of the largest international science projects after the Human Genome Project. - Bodies from all ove...

2013/02/21

CIC bioGUNE researchers to take part in the Basque Network of Food Safety Experts

 - This network will support the Food Safety Scientific Committee who advise the Basque Government(Bilbao, 21 february 2013).- CIC bioGUNE researchers -Mikel Valle, Nicol...

2013/02/14

Novel designed molecules could stop colon cancer metastasis

 - A Basque research consortium has carried out a study in mice showing that novel synthetic molecules stop the growth of colon cancer and its propagation to the liver.- ...

2013/02/13

Novel antagonists in early and late stages of cancer development.

 A multidisciplinary research team led by groups from CIC bioGUNE and the University of the Basque Country has developed a novel family of synthetic compounds with strong...

2013/02/12

Proteomics Platform at CIC bioGUNE participates in the Chromosome Centric Project...

 With the generation of a well characterized human genome map together with the availability of in depth transcriptomics, the genesis of C-HPP came from the realization t...

2013/02/06

Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty...

 Non-alcoholic fatty liver disease (NAFLD) covers a wide spectrum of liver pathologies including steatosis and non-alcoholic steatohepatitis (NASH), and may progress to c...

2013/01/17

Eight years of biosciences

 - Research centre CIC bioGUNE is celebrating its eighth anniversary with a conference by Catalan researcher Modesto OrozcoThe Basque Center for Cooperative Researc...

2013/01/09

Analía Núñez-O'Mara defends her PhD thesis on January 16th,...

 Analía Núñez-O'Mara will defend her PhD thesis, entitled " HIF Prolil Hidroxilasa 3 (PHD3), un doble centinela en la regulación de H...

2013/01/03

A new path for the future generation of glucose-measuring biosensors

- CIC bioGUNE researchers have proven the close connection between proteins that were thought to be completely independent and isolated...

2012/12/11

Famelab, el certamen internacional de monólogos científicos, llega...

FameLab nació en 2005 gracias a una idea original del Festival de Cheltenham, cuyo principal objeti...

2012/12/11

S-adenosylmethionine in Liver Health, Injury, and Cancer

 In this article, published in Physiological Reviews, Shelly Lu, from the Keck School of Medicine at the USC in Los Angeles and José Mato, from bioGUNE, review the...

2012/12/10

LKB1: Friend or foe?

- Researchers from CIC bioGUNE have found that LKB1 protein, which is commonly used to inhibit the proliferation of breast, lung and cervical cancers,...

2012/12/05

A joint study between the CNIO and CIC bioGUNE identifies metabolomic biomarkers...

 - These findings were obtained in a study of 1500 metabolites in blood, thus making it the most in-depth analysis to date in this research field.

2012/12/05

A metabolic signature predicts the biological age in mice

It is the metabolism, not the genes or the proteins, what defines better the phenotype of an organism. Consequently, the study of the unique metabolic signature that specific ...

2012/11/30

Jevgenia Tamjar defends his PhD thesis on December 3th, 2012

Jevgenia Tamjar will defend his PhD thesis, on December 3th, at 11:30 o'clock. The event will take place in "Sala anexa al Paraninfo", at t...

2012/11/29

David Fernández Ramos defends his PhD thesis on December 5th, 2012

 David Fernández Ramos will defend his PhD thesis, entitled "New Oncogenic Drivers in Hepatocellular Carcinoma: Role of the RNA Binding Protein Hu Antigen R&q...

2012/11/21

Algunos de los retos pasados y futuros de la Virología Estructural

Los virus se extienden por toda la biosfera. Algunos de ellos son patógenos para los seres humanos y los animales; otros son nuestros aliados al infectar y controlar la...

2012/11/20

¿Podemos poner a dieta el cáncer?

Arkaitz Carracedo de la Unidad de Proteómica nos explica en una entrevista en Radio Euskadi, cómo se produce y desarrolla el cáncer, y cómo las inv...

2012/11/16

Glucose-galactose binding protein: e pur si muove.

 Protein function is often coupled to internal dynamics. Periplasmic binding proteins are bi-domain bacterial proteins that can recognize many different nutrients and oli...

2012/11/15

Jornada de divulgación: Alimenta tus emociones.

 En la jornada se abordará la relación existente entre la alimentación y la felicidad, así como la influencia en nuestro estado emocional y en...

2012/10/11

CIC NETWORK reúne a representantes políticos para debatir sobre política...

Racionalizar el sistema vasco de ciencia, tecnología e innovación y alcanzar la media europea en inversión en I+D+i para el año 2015 fueron los dos...

2012/10/05

Forum on Scientific Policy this October 11th at 11:00am

Con motivo de la próxima convocatoria de elecciones al Parlamento Vasco, el próximo día 21 de octubre, la revista CIC Network -impulsada por la red d...

2012/10/01

First symposium of leading Spanish scientists who use Drosophila in their biomedical...

 More than 40 scientists from 11 centres, including CIC bioGUNE, bear out the strength of the science performed with the fruit fly in Spain.CIC bioGUNE scientists

2012/10/01

First 1st Board Meeting of the UPStream Consortium organized by CIC bioGUNE in Bilbao

 CIC bioGUNE leads the UPStream project, an excellence training program for young scientists investigating t...

2012/10/01

Metabolomics and proteomics, two key technologies in modern biology

 - International experts will discuss recent technological advances and the applications of these techniques in a conference entitled "Metabolomics & Pro...

2012/09/19

LKB1 drives Ras activation in bad prognosis hepatocellular carcinoma: A new axis...

 Hepatocellular carcinoma (HCC) accounts for more than 90% of liver cancers and it is becoming a major health problem. HCC incidence is growing with more than 750.000 ann...

2012/09/18

CIC bioGUNE y CIC biomaGUNE, dos centros, un objetivo

- Ambos centros de investigación en biociencias y biomateriales cuentan con más de 200 investigadores y han acometido inversiones por v...

2012/09/13

Iñigo Urkullu visita las instalaciones de CIC bioGUNE

 El Presidente del Partido Nacionalista Vasco (EAJ-PNV) y candidato a Lehendakari en las próximas elecciones autonómicas del 21 de octubre, Iñigo Urk...

2012/09/12

Pubmed ratings place the CIC bioGUNE Animal Unit's work in the top 10

 The publication "Clinical biochemistry parameters in C57BL/6J mice after blood collection from the submandibular vein and retroorbital plexus" (Fernandez et al...

2012/09/04

The therapeutic potential of cellular fat oxidation in bone-marrow transplants and...

 - Dr. Arkaitz Carracedo of Biogune takes part in two studies which provide evidence for a crucial role of the PML protein in the regulation of cellular fat oxida...

2012/08/20

Burning fat for cellular fitness: friend or foe?

 Fat accumulation and elimination in developed societies is an increasing health and aesthetic concern. But there is more to this process than just the impact of lipid ac...

2012/08/02

Structural and functional analyses of the interaction of archaeal RNA polymerase...

 Multi-subunit RNA polymerases (RNAPs) in all three domains of life share a common ancestry. The composition of the archaeal RNAP (aRNAP) is not identical between phyla a...

2012/07/13

HuR plays a critical role in liver fibrosis development

 Hepatic fibrosis is the common consequence of chronic liver diseases such as viral and autoimmune hepatitis, alcohol consumption, biliary obstruction, and non-alcoholic ...

2012/07/10

Synthetic solutions to combat infections

Biogune researcher, Juan Anguita, in collaboration with scientists of the University of Massachusetts, has proven the efficiency of synthetic antimicrobials.

2012/06/27

Viruses find new ancestors

 - Biogune researchers and scientists from the Universities of Oxford and Helsinki propose a radically different structure-based classification of viruses.

2012/06/26

CIC bioGUNE to hold exosome expert meeting

 - The meeting will gather the Spanish work group that studies exosomes, formed after the last conference in Gothenburg organised by the International Society for...

2012/06/04

When fat meets inflammation: NK cells are to blame

 - Researchers from the Center for Cooperative Research in Biosciences, CIC bioGUNE (Bizkaia), led by Dr. Naiara Beraza, have found that NK cells play a key role ...

2012/06/04

NK cells are the main contributors to the chronification of liver inflammation in...

 Glycine N-methyltransferase (GNMT) is the key enzyme that catabolizes S-adenosylmethionine (SAMe), the main methyl donor of the body that tightly controls cell growth, a...

2012/05/24

Ugo Mayor, from Funcional Genomic Unit, have collaborated in the book "Ubiquitin...

 Ugo Mayor, from Laboratory 4 at Functional Genomics Unit, have collaborated in the book "Ubiquitin Family Modifiers and the Proteasome" with the chapter titled...

2012/05/22

New non-invasive test for fatty liver disease diagnosis developed

 - Researchers at Biogune, in collaboration with OWL Genomics, CIBERehd and eleven hospitals and research centres from Spain, France and United States, have devel...

2012/05/07

Post-transcriptional regulation of Schwann cell development

 Schwann cells are the dominant glia cells in the peripheral nervous system (PNS) and associate with axons in peripheral nerve trunks. These cells control neuronal surviv...

2012/04/16

NASH predictive test

 In collaboration with OWL Genomics, CIBERehd, eleven ...

2012/03/20

CIC bioGUNE leads European researcher training project

 - The Basque research Centre is coordinating UPStream, an excellence training programme for young scientists investigating the biochemical process of ubiquitylat...

2012/03/19

Our researchers from Laboratory 3 at Proteomics Research Unit, have collaborated...

 Researchers from Laboratory 3 at Proteomics Research Unit, have collaborated in the book "Ubiquitin Family Modifiers and the Proteasome" with the chapter titl...

2012/03/13

Mad rabbit disease

 - Our scientists have shown that rabbits, which were previously thought to be resistant to prion diseases, can also develop such infections.

2012/03/13

Mad rabbit disease

 The ability of prions to infect some species and not others is determined by the transmission barrier. This unexplained phenomenon led to the belief that certain species...

2012/03/07

Metabolomics as a Tool for Preclinical Studies.

 Juan Manuel Falcón will participate in the MS Technology Days organized by Waters Corporation between the days 20th and 21st of March that will take place in Madr...

2012/03/01

Extracellular Microvesicles as Biological Source for Biomarker Discovery

Juan Manuel Falcón has participated in the conference "Extracellular Microvesicles as Biological Source for Biomarker Discovery", organized by the Luxembourg...

2012/02/27

Valentine Comaills will defend her PhD thesis on March 2nd

 Valentine Comaills will defend her PhD thesis, entitled "Retinoic acid and estrogen signalling pathways in tamoxifen resistant breast cancer cells", on March 2...

2012/02/27

Women and science

Our research, Edurne Berra, will participate in th...

2012/02/27

The structure of the dimerization domain of the tumor suppressor ING4 reveals the...

 A collaborative work between the groups of Ignacio Palmero (CSIC), Guillermo Montoya (CNIO) and Francisco J Blanco (CIC bioGUNE) shows that the dimerization domain of I...

2012/02/13

A prestigious American foundation will fund research at Biogune into Angelman Syndrome

 The group led by Dr. Ugo Mayor aims to identify the protein substrates responsible for this genetic disorder by using a new strategy for capturing neuronal ubi...

2012/01/31

Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding...

 According to a study carried out by researchers at CIC bioGUNE (Proteomics Unit and Proteomics Platform), the use of Tandem repeated Ubiquitin Binding Entities (TUBEs) u...

2012/01/31

New mechanism involved in the development of hepatocellular carcinoma and colon cancer.

 Hepatocellular carcinoma (HCC) is a neoplasm with poor prognosis and represents the fifth most common cancer worldwide. The research team leaded by Dr. M. Luz Mart&iacut...

2012/01/13

New therapeutic target to fight liver cancer discovered

 Researchers from the Center for Cooperative Research in Biosciences, CIC bioGUNE (Bizkaia), led by Dr. Maria Luz Martínez Chantar, have found a close rela...

2012/01/11

Recently, researchers from the Metabolomics Unit have collaborated in the new book...

 Hepatic differentiation is a complex process that requires the balanced regulation of multiple pathways. Significant advances have been made in understanding the molecul...

2012/01/11

Arkaitz Carracedo: searching the keys of cancer

Small interview to one of our researchers in Teknopolis TV show

2011/12/21

CIC bioGUNE researchers, Mikel Valle and Xabier Agirrezabala, have collaborated in...

 Mikel Valle and Xabier Agirrezabala have collaborated in the new book edited by Joachim Frank with the chapter entitled "Structure and dynamics of the ribosome as r...

2011/12/19

First Engineered Human GLTP

 The rational engineering of proteins with desirable properties is an emerging field that relies on structural studies. A research team of CICbioGUNE leaded by Lucy Malin...

2011/12/12

Methionine adenosyltransferase 1A gene deletion disrupts hepatic VLDL assembly in...

 Very-low-density lipoprotein (VLDL) secretion provides a mechanism to export triglycerides (TG) from the liver to peripheral tissues, maintaining lipid homeostasis. In n...

2011/11/04

CIC bioGUNE researchers, Ana María Aransay and Naiara Rodríguez-Ezpeleta,...

 Ana María Aransay and Naiara Rodríguez-Ezpeleta, with the collaboration of

2011/10/27

Researchers, doctors and health managers analyse prevention challenges in Bilbao

 The conference took place on Thursday 27 October, at the Basque Government's Health Office in Bilbao, and involved two debates - one on "Biomarkers for ...

2011/10/18

The second health innovation cycle will take place on the 27th of october, 2011

The second health innovation cycle, conducted by Fundación Ciencias de la Salud, will take place on the 27th of october, 2011....

2011/10/10

Discovery of a cell mechanism that reduces effectiveness of breast cancer treatment

 - Researchers from Massachusetts General Hospital, Harvard Medical School and CIC bioGUNE discover a complex cell mechanism activated by a protein - HOXB9 - that...

2011/10/10

De novo induction of amyloid-β deposition in vivo

 Alzheimer's disease (AD), the most common type of senile dementia, is associated to the buildup of misfolded amyloid-β (Aβ) in the brain. Although compelli...

2011/10/05

A new study attributes infectivity to Alzheimer's disease

 - It is still premature to conclude that this type of senile dementia...

2011/09/30

CIC bioGUNE welcomes the presentation of the new season of Teknopolis television...

 This Sunday, October 2, starts the fourteenth season of the science and technology show 'Teknopolis', produced by Elhuyar for

2011/09/26

A consortium of Basque institutions patents a product to foretell drug-related hepatic...

- The project, named LIVERTOX, involves the research centre CIC bioGUNE and the companies Owl Genomics, MD Renal and Faes Farma. It has been funded by the Bizkaia Prov...

2011/09/14

The Center for Cooperative Research in Biosciences, CIC bioGUNE, hosts from 12 to...

  - Leading researchers, including President of the Metabolomics Society, Dr. Robert Hall, will be present at the meeting. - Metabolomi...

2011/08/16

Alternate Models of RNA Looping on Nova-1 Protein in Splicing

 Nova proteins are implicated in alternate splicing regulation of specific neuronal genes and expressed exclusively in neurons. Recent issue of journal STRUCTURE (1) repo...

2011/07/29

José M Mato appointed as a member of the new Society of CSIC Presidents

 Prof. José M Mato, General Director of CIC bioGUNE and CIC biomaGUNE, has become part of the new Society of CSIC Presidents, an advisory body consisting of all fo...

2011/07/18

The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia...

 Researchers from CICbioGUNE in collaboration with the Max Planck Institute for Biophysical Chemistry have described the first initiation complex for E. coli ribosomes du...

2011/07/14

Prof. Neil Kaplowitz's special lecture available in our Video section

 Interplay of Stress Signaling and Mitochondria in Hepatotoxicity: watch it! ...

2011/07/07

The activity of SALL transcriptional repressors depends on their HDAC and their SUMOylation...

 The SALL (Spalt-like) family of zinc finger transcription factors is conserved throughout evolution and is involved in fundamental biological processes, including stem c...

2011/07/01

Rapid identification of fluorochrome modification sites in proteins

 Conjugation of a fluorescent dye to the ε-amino groups of protein lysine residues maximizes the detection sensitivity in binding assays or cell imaging. However the...

2011/06/15

Marco Piva will defend his PhD thesis on June 16, 2011 at 11:00, in Salón...

The thesis is entitled: "Implication of breast cancer stem cells in tamoxifen resistance"...

2011/06/13

La aecc concede 300.000€ a CIC bioGUNE para impulsar la investigación...

  - La Asociación Española Contra el Cáncer (aecc) y su Junta Provincial de Bizkaia conceden dos becas al centro de investigación vasc...

2011/05/19

José M Mato receives the prestigious "XLIII Jímenez Díaz...

 -> The award was granted by the Conchita Rábado de Jiménez Díaz Foundation, an institution in which Professor Mato began his scientific a...

2011/05/19

Macromolecular crowding fails to fold a globular halophilic protein in cells

 Scientists from the Structural Biology Unit in collaboration with researchers of the University of North Carolina at Chapel Hill have investigated the folding of a halop...

2011/05/02

The metabolism of cancer: Warburg effect mediated by ROS and HIF

 In Cancer cells, the reprogramming of cellular metabolism requires a glycolitic shift that provides the source of lipids, amino acids and nucleic acids needed for tumor ...

2011/04/29

miRanalyzer: an update on the detection and analysis of microRNAs in high-throughput...

 We present a new version of miRanalyzer, a web server and stand-alone tool for the detection of known and prediction of new microRNAs in highthroughput sequencing experi...

2011/04/13

Intracellular Rescue of the Uroporphyrinogen III Synthase Activity in Enzymes Carrying...

 In a collaborative effort between the Metabolomics Unit and the Structural Biology Unit, CICbioGUNE researchers have unravelled the mechanism by which the most aggressiv...

2011/04/01

Discovery of a protein that alters the nutrition of breast cancer cells

A study published in the prestigious journal Cancer Cell in March gives us a better understanding of the causes underlying the development of cancer, especially breast cancer,...

2011/03/31

Series of Lectures 2011: Prof. Sir Tom Blundell

Sir Tom Blundell, Professor and Director of Investigation in the Department of Biochemistry of the University of Cambridge (United Kingdom), have explained in a conference org...

2011/03/18

Series of Lectures 2011: Peter H. Seeberger

A bottle of refreshment, a remote control and four dolls are the means that Swiss chemistry Peter Seeberger uses to explain the importance of sugars for the health. Seeberger,...

2011/03/17

Nuria Martínez defends her PhD thesis on March 22, 2011

Nuria Martínez will defend her PhD thesis on March 22, 2011, in Salón de Grados de la Facultad de Medicina at University of Basque Country. The thesis is entitle...

2011/03/17

The sirtuin SIRT3 counteracts HIF1A-mediated metabolic reprogramming in cancer

 Researchers at Harvard Medical School in collaboration with a group from CIC bioGUNE reveal a tumor suppressive activity for the deacetylase SIRT3 in the regulation of c...

2011/03/11

Jose Luis Bilbao receives in Leasehold Palace 71 people and 40 companies that participated...

The General Deputy of Bizkaia, Jose Luis Bilbao, has received in the Leasehold Palace 71 people and 40 companies that have participated in the last years in the Aid Program of...

2011/03/03

Series of Lectures 2011: José Elguero

First day of Center's Series of Lectures 2011: Química y Salud

2011/02/11

Structural studies of a eukaryotic pore-forming toxin.

 Collaboration between the University of the Basque Country and the Structural Biology Unit in CIC bioGUNE brought some new insights into functioning of a membrane protei...

2011/02/10

Designed endonucleases in gene therapy for the Bubble Boy syndrome

 A collaborative work from research groups at CIC bioGUNE, CNIO, CRG and Cellectis shows how meganucleases can be tailored to induce homologous recombination in human cel...

2011/02/08

Oestrogen reduces the aggressiveness of breast cancer

According to a study carried out by researchers at CIC bioGUNE, led by Dr. María Vivanco, oestrogen reduces the proportion of stem cells in breast cancer, and this may ...

2011/02/03

CIC bioGUNE celebrates its sixth anniversary with a special lecture by Professor...

(Bilbao, 29 January 2011).- On 28th of January, the Centre for Cooperative Research in Biosciences, CIC bioGUNE, commemorated its sixth anniversary with a star guest, Professo...

2011/01/26

Javier Conde Vancells defends his PhD thesis on February 2nd, 2011

Javier Conde Vancells will defend his PhD thesis, entitled "Molecular and Functional Study of Exosome-like Vesicles as a New Source of Non-invasive Biomarkers for Liver D...

2011/01/20

Prohibiting hepatocytes to lose control

  Hepatocellular carcinoma (HCC) is the most frequent primary malignant tumor type in the liver. Whereas the etiology frequently involves viral infection or alcoholic ci...

2011/01/20

Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis,...

 Prohibitin 1 is a highly conserved, ubiquitously expressed protein that participates in diverse processes including mitochondrial chaperone interactions, growth and apop...

2011/01/19

Different DNA binding modes for p53 tumor suppressor

 Tumor suppressor p53 is a transcription factor that plays a central role in cell cycle control, and mutations in the protein are related to nearly 50 % of human tumours....

2011/01/11

New insight into the regulation of neuronal differentiation by Wnt proteins

Researchers from the Cell Biology and Stem Cells Unit and the Genome Analysis Group at CIC bioGUNE have discovered novel functions for two members of the Wnt protein family du...

2011/01/11

Two recent publications reveal how cancer-associated mutations in ING1 and ING4 genes...

 Collaborative work between the groups of Ignacio Palmero (Instituto de Investigaciones Biomédicas-CSIC) and Francisco J Blanco (CIC bioGUNE) has unveiled the mole...

2011/01/04

'Teknopolis': De cerca: Ugo Mayor

Aparición en Teknopolis de Ugo Mayor. Teknopolis, programa de divulgación científica emitido en ETB. Teknopolis pretende difundir contenidos cientí...

2010/12/21

The workshop on patents and their role in knowledge and technology transfer.

The workshop on patents and their role in knowledge and technology transfer took place in CIC bioGUNE on the 17th of December. The meeting was opened by the director of CIC bi...

2010/11/29

The First National Conference on Prion Diseases takes place in CIC bioGUNE

Over a hundred experts attended the First National Conference on Prion Diseases which took place in CIC bioGUNE on 25th and 26th of November. The object of the conference was ...

2010/11/16

From the lab to the market: patents as vehicles of knowledge's transfer

On the 17th of December, 2010, CIC bioGUNE will host a half day seminar on patents as vehicles of knowledge's transfer. The seminar opens at 9:30 in Atrio of the building 800....

2010/11/16

CIC bioGUNE patents a new system to treat Günter's disease

CIC bioGUNE has patented a new system that can help alleviate the symptoms of a rare, aggressive disease, congenital erythropoietic porphyria, more commonly known as Gunther's...

2010/10/29

Ubiquitination during neural development

Ubiquitination of neuronal proteins is an essential regulatory mechanism of brain function. The failure of this process has been associated with Parkinson's and Alzheimer's di...

2010/10/18

A novel strategy to isolate ubiquitin conjugates reveals a role of ubiquitination...

Ubiquitination of neuronal proteins is an essential regulatory mechanism of brain function. Its failure is associated with a number of neurodegenerative conditions, including ...

2010/10/06

Joint Workshop UPV/EHU - CIC bioGUNE: Introduction to Tomography Techniques in TEM

UPV/EHU - CIC bioGUNE Joint Workshop on tomography techniques in TEM will take place on 6th of October, at Joxe Mari Korta building, Donostia, and on 7th of October, in buildi...

2010/10/05

Estrogen affects the proportion of stem cells in the breast

Researchers from Maria Vivanco's laboratory at Cell Biology and Stem Cells Unit of CIC bioGUNE, in collaboration with clinicians from several hospitals in the Basque country a...

2010/10/01

Blood test developed for non-alcoholic fatty liver disease diagnosis

Researchers from the Metabolomics unit at CICbioGUNE-CIBERehd and OWL Genomics Ltd. (Bilbao, Spain) have used metabolomics technology to develop a blood test for non-alcoholic...

2010/09/29

Expertos internacionales en Resonancia Magnética Nuclear se dan cita en CIC...

Centro de Investigación Cooperativa en Biociencias, CIC bioGUNE, acoge estos días la V Reunión Bienal de Resonancia Magnética (RMN) que organiza la...

2010/09/27

A consortium of Biscayan entities will develop an innovative computer tool to predict...

Participating in the project, called LIVERTOX, are the research centreCIC bioGUNE, the companies Owl Genomics, MD Renal and FaesFarma, which is financed by the Pro...

2010/09/27

Blood test developed for non-alcoholic fatty liver disease diagnosis

The metabolomics-based blood test developed by OWL Genomics andCIC bioGUNE will contribute to the early diagnosis of NASH, whichaffects up to 24% of the US and Eur...

2010/09/23

Open Day Presentation for MSc students

On Thursday, 23rd of September, CIC bioGUNE will be hosting a group of Master's students from the UPV and University of Cantabria Molecular Biology and Biomedicine course. The...

2010/09/22

Critical role of LKB1-Akt pathway activation in the proliferation of hepatocellular...

Researchers from the Metabolomics unit at CICbioGUNE-CIBERehd have recently observed that the enzyme LKB1, which had been initially considered a tumor suppressor, performs the...

2010/09/10

Mutations That Cause Neurodegenerative Disorders

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a progressive neuromuscular disease that weakens and eventually destroys motor neurons (component...

2010/09/01

Structural Basis for the Wobbler Mouse Neurodegenerative Disorder

Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex: the GARP complex is involved in tethering endoso...

2010/07/28

Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

Fibroblast growth factor 21 (FGF21) is a hepatic protein that plays a critical role in metabolism, stimulating fatty acid oxidation in liver and glucose uptake in fat. Its sys...

2010/07/12

Work-shop Consorcio SICI-Consolider (Spanish Initiative on Ion Channels)

Expertos internacionales debaten en Bilbao sobre los avancesen la investigación en canales iónicos, proteínas que tienen unpapel clave en enfe...

2010/07/01

Xavier Tadeo Campillo defends his PhD thesis

On 01/07/2010, Xavier Tadeo Campillo from Oscar Millet's lab defended his PhD thesis: CStructural basis for the aminoacids composition of halophilic proteins and its relat...

2010/06/24

Advisory Board visits CIC bioGUNE

The Scientific Advisory Board visited the centre between June 16th and 18th, marking the 5th anniversary of the CIC bioGUNE Research Centre's launch. Professors Richard H....

2010/06/24

Novel Function and Intracellular Localization of Methionine Adenosyltransferase 2β...

Human methionine adenosyltransferase 2B (MAT2B) gene encodes two major splicing variants, V1 and V2, which are differentially expressed in normal tissues. Both variants are in...

2010/06/23

Liher Imaz presented his Ph.D. thesis on Wednesday, 23rd of June.

Liher Imaz successfully defended his Ph.D. thesis on Wednesday, 23rd of June, at 12 o'clock, in the "Sala Anexa al Paraninfo" at the School of Science and Techno...

2010/06/23

Post-translational modification by sumoylation is crucial to the activity of the...

The Spalt-like (Sall) family of zinc finger transcription factors is conserved throughout evolution and is involved in fundamental biological processes, as well as in embryoni...

2010/06/22

The Long History of the European People

    A large proportion of diseases that affect the welfare of human populations have a genetic component. Researchers have put in a vast effort in order to correlate ...

2010/06/01

The structure of the cellular stress sensor Gadd45α has been determined by NMR

The Gadd45 nuclear proteins modulate the response of mammalian cells to genetoxic and physiological stress. Gadd45 regulate DNA repair, cell cycle, apoptosis, and modulate tum...

2010/05/25

Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and...

The mechanism underlying prion strain mutation in the absence of nucleic acids remains unresolved. Using susceptible transgenic mice, two prevalent chronic wasting disease (CW...

2010/05/19

Harvard University and the Pasteur Institute will use CIC bioGUNE technology for...

Several international scientific institutions of wide renown, such as Harvard University and Pasteur Institute have signed collaboration agreements with the Centre for Co-oper...

2010/05/18

CIC bioGUNE researchers take part in a project to control the prion epidemic affecting...

(Bilbao, 13 May 2010).- Researchers at the Centre for Cooperative Research in Bioscience, CIC bioGUNE, in collaboration with the University of Kentucky (USA), have discovered ...

2010/05/11

A large-scale genetic study confirms that Basque people are a homogeneous group distinguishable...

(Bilbao, May 10, 2010).- A new population genetics study coordinated by the Centre for Cooperative Research in Biosciences (CIC bioGUNE) confirms that native Basque population...

2010/05/07

High-density SNP genotyping detects homogeneity of Spanish and French Basques, and...

Researchers from the Co-operative Research Center, CIC bioGUNE, from the Basque Foundation for Health Innovation and Research and from the Department of Genetics, Physical Ant...

2010/05/06

The Crystal Structure of Protein MJ1225 from Methanocaldococcus jannaschii Shows...

In mammals, 5′-AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic serine/threonine kinase subunit (alpha) and two regulatory subunit...

2010/04/28

Interacting Pathologies

Workers in Texas and Chile, including Joachin Castilla (who is now at the CIC bioGUNE Institute), have shown a link between the pathological mechanisms of Alzheimer's disease ...

2010/04/23

CIC bioGUNE y el Instituto Tomás Pascual firman un convenio de colaboración...

(Bilbao, 22 de abril de 2010).- El Centro de Investigación Cooperativa en Biociencias, CIC bioGUNE, y el Instituto Tomás Pascual han firmado un convenio de colab...

2010/04/22

Researchers from CIC bioGUNE take part in SYSGENET European Network

(Bilbao, 23rd April 2010) - The European Science Foundation (ESF), which belongs to the European Union, with its COST programme (European Co-operation in Science and Technolog...

2010/04/21

Sorting of the Alzhermer's Disease Amyloid Precursor Protein Mediated by the AP-4...

A new Signal-Adaptor Interaction between Alzheimer's Disease Amyloid Precursor Protein and the AP-4 Complex has been published in the March edition of Developmental Cell, ...

2010/04/20

A new link between Alzheimer's and prion diseases.

(Bilbao, March 2010). Researchers from the Co-operative Research Center, CIC bioGUNE, and from the University of Texas Medical School, Houston (USA), discovered a new link bet...

2010/04/16

Molecular cross talk between misfolded proteins in animal models of Alzheimer's...

The work whose results suggest an interaction between Alzheimer's and prion pathologies has been published in the March edition of The Journal of Neuroscience, with Joaqu&...

2010/04/01

Bruno Sergio Mafra Simoes defends his PhD thesis.

On 01/04/2010, Bruno Sergio Mafra Simoes from María dM Vivanco's lab defended his PhD thesis: Characterisation of human breast stem/progenitor cells. The event took...

2010/03/30

Ciclo en Tierra de Nadie: Conversaciones sobre Ciencias y Letras

El discurso científico se rige, esencialmente por la razón; el humanístico, por el sentimiento. Pero ambos, científicos y humanistas, tienen por ob...

2010/03/26

New insight into the role of Wnt-11 in prostate cancer

Researchers from the Cell Biology and Stem Cells Unit at CIC bioGUNE and Imperial College London have studied the function of Wnt-11 in prostate cancer. They report that Wnt-1...

2010/03/24

Encuentros científicos Eureka Café - Alimentos transgénicos:...

(Bilbao, 22 de marzo de 2010).- La catedrática de Bioquímica y Biología Molecular de la Universidad del País Vasco (UPV/EHU), Mertxe de Renobales y...

2010/03/24

Advances in protein quantitation using iTRAQ labeling

Proteomics Platform group at CIC bioGUNE has recently published two papers focused on the methodological aspects of protein quantitation by liquid chromatography coupled to ta...

2010/03/22

Basque Business Association's President visits CIC bioGUNE

Mr. Miguel Lazpiur, President of the Basque Business Confederation (Confebask), visited today, 22nd of March, CIC bioGUNE's facilities at the Technological Park of Bizkaia. Th...

2010/03/18

Timing is everything

Current estimates by the World Health Organization indicate that, worldwide, about 1.6 billion (BMI >25 kg/m2) adults are overweight and 400 million are obese (BMI >30 k...

2010/03/17

Diagonal-free signals

Members of the NMR Platform and the Structural Biology Unit lead by Tammo Diercks have developed a new pulse sequence that improves the acquisition of spatial restrains (NOEs)...

2010/03/15

To mutate or not to mutate: that's the question

Palms, fingers and thumbs are not just parts of the human body. They are also terms used to describe the structural elements that make up the catalytic core of fundamental enz...

2010/03/05

Bypass of an aromatic amine lesion by Y-family polymerase Dpo4.

An international team of researchers from MSKCC (USA), NYU (USA) and CICbioGUNE reported a detailed insight into the mechanisms by which Dpo4, a member of the Y-family DNA pol...

2010/03/03

Novel properties of LDL atherogenic particles uncovered by NMR

A team of researchers from CIC bioGUNE and the Hospital de la Santa Creu i Sant Pau, in Barcelona, have measured 2D-NMR spectra of the surface-exposed lysine residues of the a...

2010/02/24

A new laboratory at CIC bioGUNE will research the mad cow disease

The Prion Laboratory of the Proteomics Unit of CIC bioGUNE has started its work in the Building 502 in the Bizkaia Technology Park. The main objective of this Laboratory is &q...

2010/02/23

DNA replication with a polymerase of Y-family can cause new mutations.

Researchers from CIC bioGUNE, the Spanish Center for Co-operative Research in Biosciences(laboratory of Lucy Malinina), and their colleagues from the Memorial Sloan-Kettering ...

2010/02/16

CIC bioGUNE's 5th Anniversary Presentation file now available

CIC bioGUNE's 5th Anniversary Presentation file is now available for your perusal or download.

2010/02/11

Diagonal-Free 3D/4D HN,HN-TROSY-NOESY-TROSY.

Researchers at the CIC bioGUNE NMR facility have developed a novel NMR method for measuring crucial atomic distances for protein structure determination with unprecedented res...

2010/02/05

Nota de Prensa: CIC bioGUNE, 'buque insignia' de la apuesta vasca por las biociencias

(Derio, 29 de enero de 2010).- El centro de Investigación Cooperativa en Biociencias, CIC bioGUNE, celebra hoy viernes, día 29 de enero, su quinto aniversario de...

2010/02/05

Structure of the Tumor Suppressor ING4

The tumor suppressor ING4 regulates gene transcription by recruiting chromatin remodeling complexes to active promoters. A team of CIC bioGUNE researchers has investigated the...

2010/02/02

5th Anniversary videos

Compilation of short videos from different televisions about our 5th anniversary special conference and also about what's being done in our scientific groups.January 28th

2010/01/27

Minister of Industry and Minister of Health visit CIC bioGUNE

Basque Minister of Industry (Bernabé Unda), Vice-minister of Industry (Juan Goicolea), Minister of Health (Rafael Bengoa) and Vice-minister of Health (Olga Rivera) visi...

2010/01/27

HOXB9 promotes breast cancer progression

Aberrant expression of transcription factors has been implicated in tumorigenesis. Investigators from the Cell Biology and Stem Cells Unit at CIC bioGUNE and groups at Massach...

2010/01/22

CIC bioGUNE Platforms Brochure 2009

CIC bioGUNE Platforms Brochure 2009 is now vailable for your perusal. Please see the Press Area or the pdf file below.

2010/01/20

New insight into the regulation of axon growth by GSK-3, a protein kinase implicated...

Researchers from the Cell Biology and Stem Cells Unit at CIC bioGUNE have uncovered a function for the neuron-specific variant of the protein kinase GSK-3. The study is the ou...

2010/01/19

New insights into the regulation of liver de-differentiation, development and human...

HuR/Methyl-HuR and AUF1 provide a post-transcriptional regulatory mechanism of MAT1A and MAT2A, the two isoforms of the MAT enzyme, responsible for the levels of hepatic S-ade...

2010/01/04

CIC bioGUNE Annual Report 2009

CIC bioGUNE Annual Report 2009 is now available for download: please see Press Area menu entry or click here to...

2009/12/16

Proteins that 'resist' salt.

Structural Basis for the Aminoacid Composition of Proteins from Halophilic Archea.A group of researchers from CIC bioGUNE, led by Dr. Oscar Millet, has ...

2009/12/11

Protein MJ0100: an open-to-closed conformational change in its CBS motif pair.

Binding of 5'-methylthioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pair.The group of Alfon...

2009/12/04

BCAM - CIC bioGUNE Workshop on Cell Population Dynamics takes place on the 4th of...

Cell Population Dynamics - laboratory analysis and mathematical modelling.The workshop, to take place on the 4th of December in BCAM (Basque Center For Applied Mathematics, Bi...

2009/12/03

The Minister of Health visits CIC bioGUNE's Technological Platforms.

Yesterday, December the 2nd, the Minister of Health in the Basque Government, Rafael Bengoa, visited CIC bioGUNE's facilities in the Technological Park of Bizkaia, for the fir...

2009/11/18

Illumina workshop at CIC bioGUNE on November 25th.

Illumina workshop will take place in CIC bioGUNE on November 25th ( Atrio 800, 10.30- 13.30 ). Please see the pdf file for the progamme and further information. ...

2009/11/10

Symantec workshop takes place in CIC bioGUNE on the 10th of November

2009/11/09

Basque Government's Minister of Industry and Innovation Visits CIC bioGUNE

The Minister of Industry and Innovation of the Basque Government, Bernabé Unda, visited today the CIC bioGUNE facilities in the Technological Park of Bizkaia; it was hi...

2009/11/03

The role of surface tension in protein stability

The group of Oscar Millet from the Structural Biology Unit of CIC bioGUNE has recently published a study on the influence of the surface tension on protein stability. Specific...

2009/10/28

CIC bioGUNE and Proteomika create the largest catalogue of proteins from endometrial...

Researchers from the Cooperative Research Centre in Biosciences CIC bioGUNE and from a Basque company Proteomika have published the most comprehensive proteomic characterisati...

2009/10/27

Researchers from CIC bioGUNE identify a risk gene that affects regeneration of the...

Researchers from the Biosciences Co-operative Research Centre, CIC bioGUNE, and the Centre for Networked Biomedical Research into Hepatic and Digestive Diseases (CIBERehd) hav...

2009/10/21

The Deputy Minister of Industry and Innovation Visits CIC bioGUNE

The Deputy Minister for Industry and Innovation in the Basque Government, Pedro Hernandez, visited today the facilities of the Structural Biology Unit, CIC bioGUNE, in Bizkaia...

2009/10/07

SGI Roadshow 2009 seminar took place in CIC bioGUNE on the 7th October, 2009

SGI Roadshow 2009 seminar took place in CIC bioGUNE on the 7th October, 2009 between 9:30 and 13:00. Please see the programme for more information. See SGI web site

2009/10/02

EMBO Reports describes the new tool for capturing ubiquitylated proteins (TUBEs),...

On October the 2nd EMBO Reports published a paper describing new tools...

2009/09/30

CIC bioGUNE- VICOMTECH joint workshop took place on the 2nd of October, 2009

CIC bioGUNE- VICOMTECH joint workshop held at CIC bioGUNE, on the 2nd of October, 2009.

2009/09/25

Ane Fullaondo defended her doctoral thesis on September 29th, 2009.

Ane Fullaondo from D. Gubb's lab presented her doctoral thesis entitled "The role of Spn42Dd serpin in the innate immune response" on September 29th, 2009. The event...

2009/09/21

Comprehensive proteomic analysis of human endometrial fluid aspirate published by...

The group of Felix Elortza at the Proteomics Platform of CIC bioGUNE has recently published a comprehensive proteomic characterization of the human endometrial fluid from heal...

2009/09/15

CIC bioGUNE Laboratories are offering the opportunity to undertake Master/PhD studies...

2009/09/15

CIC bioGUNE open day for PhD students took place on September 21st.

Open day for potential PhD students took place in CIC bioGUNE on the 21st of September. After a series of talks delivered by the heads of several of the CIC bioGUNE's labo...

2009/09/14

Alzheimer Research Project: sample collection notes

Alzheimer Disease Research Project Sample Collection.We thank all the people who have shown interest in the research project related to Alzheimer Disease carried out by severa...

2009/09/10

CIC bioGUNE - FAES FARMA Joint Workshop took place in CIC bioGUNE on September 8th....

FAES FARMA presentations and and CIC bioGUNE presentations were given by the scientists from both centers, following the general introduction talks by José M Mato and M...

2009/09/07

Detection of protein SUMOylation in vivo

The group of Manuel S. Rodríguez from the Proteomics Unit of CIC bioGUNE, working in collaboration with Prof. R.T. Hay from the University of Dundee, has recently publi...

2009/08/13

Loss of GNMT impairs liver regeneration

Researchers at the CICbioGUNE-CIBERedh led by José Maria Mato and M-Luz Martínez-Chantar, in collaboration with investigators at the Keck School of Medicine (USA...

2009/08/06

Adriana Rojas Cardona joins CIC bioGUNE as the leader of X-ray Crystallography Platform.

Researcher Adriana Rojas Cardona has taken up the position of manageress at the X-ray Crystallography platform of CIC bioGUNE's Structural Biology Unit, where she joins th...

2009/07/27

Joaquín Castilla joins the Proteomic Unit at CIC bioGUNE to research prions,...

Thanks to the Basque Government's Ikerbasque Programme, CIC bioGUNE's Proteomic Unit has just gained a new Group Leader, Joaquín Castilla, who will focus his r...

2009/07/23

A North American bio-company to market a CIC bioGUNE product for developing anti-cancer...

The CIC bioGUNE Biosciences Research Centre has reached an agreement with the North American biotechnology firm LifeSensors to license them to market a product (TUBEs) which w...

2009/07/23

PHDs silencing promotes therapeutic revascularisation

Therapeutic neovascularisation represents an alternative treatment modality for patients with advanced ischemic coronary or peripheral artery occlusive disease. The hypoxia-in...

2009/07/22

Researchers from CIC bioGUNE find a way to treat ischemic pathologies

A team of researchers from CIC bioGUNE, led by Dr Edurne Berra from the Cellular Biology and Stem Cell Unit, alongside a team from Paris' Cardiovascular Research Centre (INSER...

2009/07/21

Necrotic serpin, the protein that checks fungal growth.

A group of researchers from CIC bioGUNE and the Andalusian Developmental Biology Centre, led by the head of the Functional Genomics Unit - Laboratory 3, David Gubb from the U....

2009/07/21

Researchers from CIC bioGUNE and Columbia University conduct joint research into...

Researchers from CIC bioGUNE's Structural Biology Unit and Columbia University (New York) have conducted a joint research project, published in the prestigious scientific ...

2009/07/15

Luis Espinosa Hevia presented his doctoral thesis on July 17th

Luis Espinosa Hevia from Luis Parada's lab defended his doctoral thesis entitled "Organización del genoma durante hepatocarcinogénesis" on July 17th, 2...

2009/07/14

CIC bioGUNE & FAES FARMA special conference to be held on September 8th

CIC bioGUNE & FAES FARMA joint workshop is to be held on September 8th, 2009 in CIC bioGUNE, building 800. The conference will start with general introductory talks given ...

2009/07/10

CIC bioGUNE scientists give talks in the summer conference in Convento de Santo Domingo...

The summer conference entitled "CUANDO LA QUÍMICA SE HACE BIOLOGÍA Y VICEVERSA" took place in Convento de Santo Domingo in Ronda between 6th and 10th o...

2009/07/06

Mikel Valle, a CIC bioGUNE researcher, wins the 2009 EBSA Prize

Mikel Valle, head of one of the research groups at the CIC bioGUNE Structural Biology Unit, has won the 2009 EBSA Prize, an award granted by the European Biophysical Societies...

2009/07/06

Miriam Hernando Rodríguez from José Luis Zugaza's lab defended her...

Miriam Hernando Rodríguez from José Luis Zugaza's lab, defended her doctoral thesis entitled "Implicación de la GTPase Rac1 en la señalizaci&o...

2009/06/29

Researchers from CIC bioGUNE develop a bioinformatics tool for interpreting the results...

 A team of researchers from the Functional Genomic Unit of CIC bioGUNE, led by Ana María Aransay, have developed a bioinformatics tool capable of analysing and int...

2009/06/29

The site of the uptake and degradation of the Necrotic serpin in Drosophila melanogaster...

A new study of the uptake and degradation of the Necrotic serpin in Drosophila melanogaster, carried out by the Functional Genomic group led by David Gubb, was published in th...

2009/06/26

Onetsine Arrizabalaga de Mingo from José Luis Zugaza's lab defended her doctoral...

Onetsine Arrizabalaga de Mingo from José Luis Zugaza's lab defended her doctoral thesis entitled "Papel de las GTPasas de la familia Rho y la glucógeno fosf...

2009/06/22

CIC bioGUNE and the Biophysics Unit at the UPV/EHU to perform research at the ESRF...

The European Synchrotron Radiation Facility (ESRF) has awarded a Block Allocation Group (BAG) to the Structural Biology Unit of CIC bioGUNE, to be used in collaboration with t...

2009/06/22

Sergio Hernández from Jim Sutherland's lab defends his doctoral thesis

Sergio Hernández from Jim Sutherland's lab defends his doctoral thesis entitled "Functional and molecular characterisation of LMO6, a PET-LIM protein" on Mond...

2009/06/19

A multidisciplinary approach using a combination of biophysical techniques reveals...

A multidisciplinary approach using a combination of biophysical techniques, applied by researchers from the CIC bioGUNE's Structural Biology Unit, has recently revealed unexpe...

2009/06/17

The joint CIC bioGUNE - CIC microGUNE workshop on July 13th, 2009

The joint CIC bioGUNE - CIC microGUNE workshop will take place at CIC bioGUNE's building 800 in Derio, on July 13th, 2009. Following general introductory talks by Carlos L...

2009/06/17

Pyruvate carboxylase structural studies

Researchers from the CICbioGUNE's Structural Biology Unit have recently resolved the three-dimensional structure for pyruvate carboxylase using cryo-electron microscopy. Pyruv...

2009/06/03

miRanalyzer, a new web server tool for smallRNAs deep-sequencing analysis, has been...

A paper by Michael Hackenberg et al, presenting miRanalyzer, a microRNA detection and analysis tool, was published in May's Web Server issue of Nucleic Ac...

2009/06/01

Sandra Soukup from David Gubb's lab presented her PhD thesis on June the 5th, 2009

Sandra Soukup from David Gubb's lab defended her doctoral thesis entitled "Degradation of the Necrotic serpin in Drosophila" on June the 5th, 2009 at 12:00 o'clock a...

2009/05/28

Roland Hjerpe defended his PhD thesis on June 3rd, 2009

Roland Hjerpe from Manuel Rodríguez's lab defended his doctoral thesis entitled "p53, a crucial target of Mdm2 and the UPS: studies of specificity and method devel...

2009/05/28

Ricardo Sánchez Pérez from Francisco Blanco's lab presented his PhD...

Ricardo Sánchez Pérez from Francisco Blanco's lab defended his doctoral thesis titled "Análisis por RMN de las proteínas PCNA y Gadd45alfa, y ...

2009/05/20

Jonatan Sánchez García and Mercedes Vázquez Chantada presented...

Two PhD students from CIC bioGUNE presented their doctoral theses on June the 1st, 2009, at 12 o'clock, at Facultad de Ciencias y Tecnología, UPV/EHU. Jonatan S&aac...

2009/05/07

CIC bioGUNE - BCAM Joint Workshop took place in CIC bioGUNE on May 11th.

CIC bioGUNE and BCAM (Basque Center for Applied Mathematics) have organized a joint workshop where scientists from both centers presented their work. It is hoped that the conf...

2009/05/07

PLoS BIOLOGY publishes new work from a team of researchers led by Dr. Abrescia, investigating...

Acid-loving Archaeon Reads DNA with Enzyme Strikingly Similar to Our Own.Some extremophilic Archaea organisms read their DNA using enzymes surprisingly simila...

2009/05/06

Researchers at CIC bioGUNE reveal evolution of prehistoric protein in the human body.

Research carried out by the Basque Centre for Biosciences, CIC bioGUNE, and the universities of Yale, Harvard and Oxford, published in this May's edition of PLoS Biology, show...

2009/04/29

CIC bioGUNE researcher contributes to the scientific magazine Investigación...

A scientific report by CIC bioGUNE researcher Oscar Millet dedicated to protein motion as studied by NMR spectroscopy has been published in the April's issue of the scient...

2009/04/29

A round table discussion "MUJER Y CIENCIA" at the University Rey Juan Carlos...

A round table discussion entitled "Mujer y Ciencia" has taken place today at the University Rey Juan Carlos in Madrid, within the cycle of conferences "La Mujer...

2009/03/23

El País reports on Ana M. Aransay's talk in Eureka Cafe

'What do we know about ourselves?' was the title of the talk, with an invitation to disscussion, which was eagerly taken up by a 50-odd strong audience of all ages and...

2009/02/18

Evidence for LKB1/AMPK/eNOS cascade regulated by HGF, S-adenosylmethionine, and NO...

Researchers at the CIC bioGUNE, in Bilbao, and colleagues at the Keck School of Medicine, in Los Angeles, have discovered a new biochemical pathway, involving the genes LKB1, ...

2009/02/11

CIC Network Forum 2009 held on February 19th, in CIC bioGUNE

CIC Network Forum 2009 took place on February 19th, in CIC bioGUNE, Technological Park of Bizkaia, Derio.

2009/01/12

CICbioGUNE held an open day for potential PhD students on 22nd of January, 2009

On the 22nd of January, 2009, CIC bioGUNE held an open day aimed at potential PhD students interested in participating in a research project in the centre. All the laboratorie...

2008/12/05

Custom meganucleases induce chromosomal gene repair without detectable genotoxicity.

Custom meganucleases that recognize and cleave a specific sequence of the human xeroderma pigmentosum gene induce chromosomal gene repair without detectable genotoxicity; the ...

2008/12/03

URBE (Usuarios Resonancia Bruker Española) 2008 conference takes place in...

On 27th and 28th of November, CICBiogune and Bruker Española organized the URBE (Usuarios Resonancia Bruker Española) 2008 conference. More than 60 people from a...

2008/12/01

Atos Origin collaborates with CIC bioGUNE designing a grid-based solution to achieve...

One of the latest's challenges for CIC bioGUNE is to deal with the increasing computing power required to analyze huge amounts of genetic data, to find patterns and compare be...

2008/11/06

Dr. María dM Vivanco, a CIC bioGUNE researcher, has been awarded a research...

Dr. María dM Vivanco, Group Leader of the Molecular Biology and Stem Cell Unit at CIC bioGUNE, has obtained a research bursary awarded by the Spanish Foundation for Sen...

2008/10/31

Cryo-electron microscopy shows ribosomes on the move.

Researchers from the Structural Biology Unit of CICbioGUNE have captured the structure of ribosomes during the movement of tRNAs. The study performed using cryo-EM analysis sh...

2008/10/22

CIC bioGUNE is to take part in the NANOTHER European Cancer Research Project

CIC bioGUNE is one of 18 entities which are going to be taking part in NANOTHER: a European research project in which advances in nanotechnology will be applied to cancer ther...

2008/10/15

Sumoylation in the synthesis of steroid hormones: smt3 is required for Drosophila...

A group from CIC bioGUNE, in collaboration with groups from Barcelona and Stockholm University, have demonstrated a role for sumoylation in the synthesis of steroid hormones. ...

2008/10/08

CIC bioGUNE presents its Technology Platforms to CIBERehd

On 7th of October CIC bioGUNE presented its Technology Platforms to the Centre for Networked Biomedical Research, CIBERehd, during the workshop held in the Basque centre's hea...

2008/10/08

Abnormal methionine metabolism leads to non-alcoholic fatty liver disease (NAFLD)...

Researchers at the CIC bioGUNE and the University of Southern California, Keck School of Medicine, in Los Angeles, have published an article in The Annual Review of Nutrition ...

2008/09/22

CIC bioGUNE participates in two projects funded by NIH: liver injury and colon cancer...

The National Center for Complementary & Alternative Medicine (NCCAM), part of the US National Institutes of Health (NIH), has awarded two grants totaling US$ 2.57 million ...

2008/09/19

Bilbao hosts the 31st Conference of the Spanish Biochemistry and Molecular Biology...

From 10 to 13 September, Bilbao hosted the 31st Conference of the Spanish Biochemistry and Molecular Biology Society (SEBBM), organised, among others, by CIC bioGUNE. This pre...

2008/09/19

CIC bioGUNE's Animal Unit receives the highest international accreditation for...

The Animal Unit of the CIC bioGUNE has been awarded the "Full Accreditation" by the Association for Assessment and Accreditation of Laboratory Animal Care (...

2008/09/03

The European network Inproteolys holds its first course on specialized methods of...

Between 1st and 5th September, at the premises of CIC bioGUNE, the European network for the study of intra-cellular proteolysis, Inproteolys, held its first course on speciali...

2008/09/03

International experts are to study the latest breakthroughs in genetic research into...

The 11th European Workshop on Cytogenetics and Molecular Genetics of Solid Tumours, organized by Dr. Luis Antonio Parada, Group Head of the Cellular Biology and Stem Cells Uni...

2008/07/28

The "Asociación de Cáncer de Mama de Bizkaia" visited the...

The "Asociación de Cáncer de Mama de Bizkaia" visited the "Breast Cancer and Stem Cells" laboratory on the 12th of June. Several members, inc...

2008/07/16

International experts in alcoholism and cirrhosis are to meet in Bilbao on 17 and...

The third International Symposium on Alcoholic Liver and Pancreatic Diseases (ALPD) and Cirrhosis will be held in Bilbao on 17 and 18 July. This prestigious event is being org...

2008/07/09

Researchers at the Structural Biology Unit and Genotyping Laboratory of CICbioGUNE...

Investigators from the CICbioGUNE's Structural Biology Unit will participate in the Consolider research project SICI (The Spanish Ionic Channel Initiativ...

2008/07/03

The dual face of PHDs

A team at CIC bioGUNE in collaboration with investigators at the CNRS-UMR 6543 in France has proved that the PHDs, which are immediately inactivated by the lack of oxygen, bec...

2008/06/05

Professor Liang Tong gives a talk on the metabolism of fatty acids during the second...

As part of the second Workshop organised by the Structural Biology Unit at CIC bioGUNE, on 29 May, Professor Liang Tong gave a talk entitled: 'Structural studies of fatty acid...

2008/05/30

Basic Course on Proteomics at CIC bioGUNE: 3th of July 2008

The course will focused mainly in mass spectrometry but will also cover different basic aspect as:Overview of proteomic experiments, sample preparation guides, introduction to...

2008/05/20

PROTEOLYSIS COURSE.

CIC bioGUNE 1-7 SEP, 2008

http://www.inproteolys.eu/index.cfm...

2008/05/20

2nd Structural Biology Workshop: Signal Transduction.
CIC bioGUNE, 29-30 May,...

2008/05/20

Darwin and Wallace, 150 Years of Discovering Evolution: Lecture description and multimedia...

The lecture description and multimedia content is available courtesy of FBBVA, in

2008/04/30

Ginés Morata closes the 'Darwin and Wallace' cycle with a talk entitled 'Genes,...

On 29 April, Ginés Morata, a researcher at the Supreme Council for Scientific Research's Centre for Molecular Biology and the Autonomous University of Madrid (UAM), and...

2008/04/23

Ana Talamillo and Jonatan Sánchez from the group of Rosa Barrio were awarded...

Talamillo and co-workers showed that lack of sumoylation arrests larval development, probably due to the impairment of lipid droplets entrance into the gland responsible for s...

2008/04/21

Miguel Delibes de Castro talks about 'Evolutionism and nature conservation' in the...

Miguel Delibes de Castro, a research lecturer with the CSIC (Supreme Council for Scientific Research) at the Doñana Biological Station and winner of the National Award ...

2008/04/10

CIC bioGUNE researcher, Ana María Aransay, gave a talk on Personalised Medicine...

On 8 April in Bilbao, the head of the Genotyping Laboratory at the Functional Genomics Unit of CIC bioGUNE, Ana María Aransay, gave a talk entitled "Human evolution and...

2008/04/08

Loss of GNMT induces liver cancer

A team at CIC bioGUNE, in collaboration with investigators at the University of Vanderbilt, the CNIO, and the Keck School of Medicine, have discovered that knockout mice defic...

2008/03/14

Fern Elsdon-Baker analyses heredity theory in Darwin's thought

Fern Elsdon-Baker, lecturer in the History of Science at the University of Durham and member of the British Society for the History of Science, delivered a lecture in Bilbao o...

2008/03/12

In the series of lectures on Darwin and Wallace, Juan Uriagereka discourses on the...

Juan Uriagereka, the linguist and Professor of the University of Maryland, delivered a lecture entitled "Desde abajo de la gramática" (Grammar from below) on ...

2008/03/10

Markel Olano, Head of the Gipuzkoa Government, visits CIC biomaGUNE's facilities

On 5th March the Head of the Gipuzkoa Government, Markel Olano, visited CIC biomaGUNE's facilities at Miramón Technology Park in Donostia, accompanied by the Gipuzk...

2008/03/10

MD Renal, CIC biomaGUNE's first spin-off, gets under way

The Cooperative Biomaterials Research Centre, CIC biomaGUNE, has created its first spin-off, Donostia-based MD Renal S.L, which has its sights set on becoming an international...

2008/03/04

The archaeologist Eudald Carbonell participated in the series of talks organised...

On 28 February, Eudald Carbonell, professor of Prehistory at the Universitat Rovira i Virgili in Tarragona, gave a talk in Bilbao entitled 'Sierra de Atapuerca: evolutionary g...

2008/03/03

Peter Bowler opens the cycle of talks entitled 'Darwin and Wallace. 150 years of...

On 26 February, Peter Bowler, Professor in the History of Science at Queen's University Belfast and former Chairman of the British History of Science Society, officially opene...

2008/02/19

The State Secretary for Universities and Research, Miguel Ángel Quintanilla,...

A delegation of the Ministry of Education and Science, made up by The State Secretary for Universities and Research, Miguel Ángel Quintanilla, and the general manager o...

2008/02/15

The General Secretary of the Socialist Party in the Basque Country, Patxi López,...

The General Secretary of the Socialist Party in the Basque Country, Patxi López, visited the CIC bioGUNE facilities on the 12th of February in order to receive first-ha...