0000-0002-8271-612XAna M Aransay obtained her BSc in Biology from the from the University of the Basque Country (UPV/EHU) and her PhD from the Medicine of the University of Crete, Greece, under the supervision of Prof. Yannis Tselentis. During this period, she learnt all the key Molecular Biology techniques (isoenzymes, DNA cloning, DNA sequencing, PCR, PCR-RFLP, etc.) and the fundamentals of infectious disease diagnosis, species molecular typing, phylogeny and epidemiological studies.
After getting her PhD in 1999, Dr. Aransay was awarded two consecutive postdoctoral research grants from the Basque Country Government to work on a project focused on the population genetics of parasitic disease vectors. Initially, she joined the laboratory of Dr. Paul D. Ready at the Entomology Department of the Natural History Museum of London (UK) and later, she relocated to Madrid to continue her research at the National Centre of Microbiology of the Instituto de Salud Carlos III, under the supervision of Dr. Ricardo Molina.
In 2004, Dr. Aransay joined CIC bioGUNE as the Genome Analysis Platform Manager to support internal users and offer collaborative research to external researchers. The platform's main objectives include developing high-throughput technologies to enable genome characterization. This involves investigating DNA variants at the whole-genome level, analyzing the expression of coding and non-coding RNAs, and profiling DNA methylation. While the primary focus is on biomedical projects, the platform's services are also applicable to a wide range of biological research questions.
Latest Publications
2023
2022
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Monika Gonzalez
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Jose Ezequiel Martin Rodriguez
TECHNICIANS / DOCTORAL CANDIDATES -
Nuria Macias
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Laura Bárcena
Members
SPECIALISTLatest Publications
BirthSeq, a new method to isolate and analyze dated cells in different vertebrates.
Rueda-Alana, Eneritz; Grillo, Marco; Vazquez, Enrique; Salas, Sergio Marco; Senovilla-Ganzo, Rodrigo; Escobar, Laura; Quintas, Ana; Benguria, Alberto; Aransay, Ana Maria; Bengoa-Vergniory, Nora; ...
Development (Cambridge, England)
2024-06-10
Propionate and butyrate counteract renal damage and progression to chronic kidney disease
Corte-Iglesias, V; Saiz, ML; Andrade-Lopez, AC; Salazar, N; Bernet, CR; Martin-Martin, C; Borra, JM; Lozano, JJ; Aransay, AM; Diaz-Corte, C; Lopez-Larrea, C; Suarez-Alvarez, B;
NEPHROLOGY DIALYSIS TRANSPLANTATION
2024-05-24
rhBMP-2 induces terminal differentiation of human bone marrow mesenchymal stromal cells only by synergizing with other signals
Kathami, N; Moreno-Vicente, C; Martin, P; Vergara-Arce, JA; Ruiz-Hernández, R; Gerovska, D; Aransay, AM; Araúzo-Bravo, MJ; Camarero-Espinosa, S; Abarrategi, A;
STEM CELL RESEARCH & THERAPY
2024-04-29
Exploring kidney allograft rejection: A proof-of-concept study using spatial transcriptomics.
Martin-Martin, Cristina; Suarez-Alvarez, Beatriz; Gonzalez, Monika; Torres, Irina B; Bestard, Oriol; Martin, Jose E; Barcelo-Coblijn, Gwendolyn; Moreso, Francesc; Aransay, Ana M; Lopez-Larrea, ...
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
2024-04-29
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Ayuso-García, P; Sánchez-Rueda, A; Velasco-Avilés, S; Tamayo-Caro, M; Ferrer-Pinós, A; Huarte-Sebastian, C; Alvarez, V; Riobello, C; Jiménez-Vega, S; Buendia, I; Cañas-Martin, J; Fernández-Susavila, ...
SCIENCE ADVANCES
2024-04-12
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...
CELL REPORTS
2024-03-26
Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation
Peña-Cearra, A; Palacios, A; Pellon, A; Castelo, J; Pasco, ST; Seoane, I; Barriales, D; Martin, JE; Pascual-Itoiz, MA; Gonzalez-Lopez, M; Martín-Ruiz, I; Macías-Cámara, N; Gutiez, N; Araujo-Aris, ...
COMMUNICATIONS BIOLOGY
2024-02-16
Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury
Diaz-Bulnes, P; Rodríguez, RM; Banon-Maneus, E; Saiz, ML; Bernet, CR; Corte-Iglesias, V; Ramirez-Bajo, MJ; Lazo-Rodriguez, M; Tamargo-Gómez, I; Rodrigues-Diez, RR; Sanz, AB; Diaz-Corte, C; Ruiz-Ortega, ...
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
2024-01-01
Global and single-nucleotide resolution detection of 7-methylguanosine in RNA.
DAmbrosi, Silvia; Garcia-Vilchez, Raquel; Kedra, Darek; Vitali, Patrice; Macias-Camara, Nuria; Barcena, Laura; Gonzalez-Lopez, Monika; Aransay, Ana M; Dietmann, Sabine; Hurtado, Antonio; Blanco, ...
RNA biology
2024-01-01
SERS analysis of cancer cell- secreted purines reveals a unique paracrine crosstalk in MTAP- deficient tumors
Valera, PS; Plou, J; Garcia, I; Astobiza, I; Viera, C; Aransay, AM; Martin, JE; Sasselli, IR; Carracedo, A; Liz-Marzan, LM;
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2023-12-26
Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis
Peña-Cearra, A; Castelo, J; Lavín, JL; Gonzalez-Lopez, M; Pascual-Itoiz, MA; Fuertes, M; de Juan, VG; Bárcena, L; Martín-Ruiz, I; Pellón, A; Seoane, I; Barriales, D; Palacios, A; Fullaondo, ...
GUT MICROBES
2023-12-18
Long Non-Coding RNA Signatures in the Ileum and Colon of Crohn's Disease Patients and Effect of Anti-TNF-α Treatment on Their Modulation
Baldan-Martin, M; de Célix, CR; Orejudo, M; Moreno, LO; Fernández-Tomé, S; Soleto, I; Ramirez, C; Arroyo, R; Fernández, P; Santander, C; Moreno-Monteagudo, JA; Casanova, MJ; Casals, F; Casabona, ...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023-11-01
Factor-inhibiting HIF (FIH) promotes lung cancer
García-del Río, AGD; Prieto-Fernández, E; Egia-Mendikute, L; Antonana-Vildosola, A; Jimenez-Lasheras, B; Lee, SY; Barreira-Manrique, A; Zanetti, SR; de Blas, A; Velasco-Beltrán, P; Bosch, A; ...
JCI INSIGHT
2023-10-23
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
Pena-Cearra, A; Song, DG; Castelo, J; Palacios, A; Lavin, JL; Azkargorta, M; Elortza, F; Fuertes, M; Pascual-Itoiz, MA; Barriales, D; Martin-Ruiz, I; Fullaondo, A; Aransay, AM; Rodriguez, H; ...
NPJ BIOFILMS AND MICROBIOMES
2023-10-07
N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
Garcia-Vilchez, R; Anazco-Guenkova, AM; López, J; Dietmann, S; Tomé, M; Jimeno, S; Azkargorta, M; Elortza, F; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Sánchez-Martín, MA; Huertas, P; Durán, ...
ONCOGENE
2023-09-02
Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Capelo-Diz, A; Lachiondo-Ortega, S; Fernández-Ramos, D; Cañas-Martín, J; Goikoetxea-Usandizaga, N; Serrano-Maciá, M; González-Rellan, MJ; Mosca, L; Blazquez-Vicens, J; Tinahones-Ruano, A; Fondevila, ...
CELL METABOLISM
2023-08-08
METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer
García-Vilchez, R; Anazco-Guenkova, AM; Dietmann, S; López, J; Morón-Calvente, V; DAmbrosi, S; Nombela, P; Zamacola, K; Mendizabal, I; García-Longarte, S; Zabala-Letona, A; Astobiza, I; Fernández, ...
MOLECULAR CANCER
2023-07-29
Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes
Cano, A; Vazquez-Chantada, M; Conde-Vancells, J; Gonzalez-Lahera, A; Mosen-Ansorena, D; Blanco, FJ; Clément, K; Aron-Wisnewsky, J; Tran, A; Gual, P; García-Monzón, C; Caballería, J; Castro, ...
BIOMEDICINES
2023-02-01
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, J; Diaz-Nuñez, M; Clos-García, M; Lainz, L; Iglesias, M; Díez-Zapirain, M; Rabanal, A; Bárcena, L; González, M; Lozano, JJ; Marigorta, UM; González, E; Royo, F; Aransay, AM; Subiran, ...
HUMAN REPRODUCTION
2022-08-27
Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis
Peña-Cearra, A; Pascual-Itoiz, MA; Lavin, JL; Fuertes, M; Martín-Ruiz, I; Castelo, J; Palacios, A; Barriales, D; Fullaondo, A; Aransay, AM; Rodríguez, H; Anguita, J; Abecia, L;
SCIENTIFIC REPORTS
2022-06-15