Ana M Aransay
amaransay
Ana M Aransay
PLATFORM MANAGER
Genome Analysis Platform
Orcid: 000-0002-8271-612X
Email: amaransay@cicbiogune.es
Phone: 4421 / 944 061 325
Address: Bizkaia Science and Technology Park, building 801A, Derio (Bizkaia)

Ana M. Aransay got a Bachelor’s degree in Biology (specialty: Fundamental Biology) at the University of the Basque Country (UPV/EHU) in 1992. During training and her PhD in Molecular Entomology (granted by a European training program and the Basque Government, respectively) in the Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete (Greece), under the supervision of Prof. Yannis Tselentis, she learned insect Taxonomy and key Molecular Biology techniques such as isoenzyme analysis, DNA cloning, DNA sequencing, PCR and PCR–RFLP, and the fundamentals of diagnosis and molecular characterization of parasite species for phylogeny and epidemiological studies. After receiving her PhD in 1999, she got two consecutive postdoctoral research fellowships from the Basque Government to carry out a project on the population genetics of Leishmania insect-vectors. Her postdoctoral research work was conducted from 1999 to 2004, first in the Department of Entomology at the Natural History Museum in London (UK), under the supervision of Dr. Paul D. Ready, and later, in the National Center for Microbiology, Institute of Health Carlos III of Madrid (Spain), under the supervision of Dr. Ricardo Molina. Since November 2004, she is responsible for the Platform for Genome Analyses of CIC bioGUNE (Derio, Spain), where the main objectives are the development of high-throughput technologies to provide services that allow the characterization of genomes from different points of view. In particular, this platform handles molecular biology techniques and bioinformatics analyses applied to the investigation of DNA variants at the whole genome level, the expression of coding and non-coding RNAs and the characterization of DNA methylation profiles, mainly for projects within the Biomedical field, but applicable to any other biological question

Latest Publications
Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells
Lozano-Ruiz, B;Tzoumpa, A;Martinez-Cardona, C;Moreno, D;Aransay, AM;Cortazar, AR;Pico, J;Peiro, G;Lozano, J;Zapater, P;Frances, R;Gonzalez-Navajas, JM
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022-02-01
Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure
Zhang, IW;Curto, A;Lopez-Vicario, C;Casulleras, M;Duran-Guell, M;Flores-Costa, R;Colsch, B;Aguilar, F;Aransay, AM;Lozano, JJ;Hernandez-Tejero, M;Toapanta, D;Fernandez, J;Arroyo, V;Claria, J
JOURNAL OF HEPATOLOGY
2022-01-01

2021

Identification of proximal SUMO-dependent interactors using SUMO-ID
Barroso-Gomila, O;Trulsson, F;Muratore, V;Canosa, I;Merino-Cacho, L;Cortazar, AR;Perez, C;Azkargorta, M;Iloro, I;Carracedo, A;Aransay, AM;Elortza, F;Mayor, U;Vertegaal, ACO;Barrio, R;Sutherland, ...
NATURE COMMUNICATIONS
2021-11-18
SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes
Giordano, I;Pirone, L;Muratore, V;Landaluze, E;Perez, C;Lang, V;Garde-Lapido, E;Gonzalez-Lopez, M;Barroso-Gomila, O;Vertegaal, ACO;Aransay, AM;Rodriguez, JA;Rodriguez, MS;Sutherland, JD;Barrio, ...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021-09-21
Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients
Rodriguez, RM;Hernandez-Fuentes, MP;Corte-Iglesias, V;Saiz, ML;Lozano, JJ;Cortazar, AR;Mendizabal, I;Suarez-Fernandez, ML;Coto, E;Lopez-Vazquez, A;Diaz-Corte, C;Aransay, AM;Lopez-Larrea, C;Suarez-Alvarez, ...
FRONTIERS IN IMMUNOLOGY
2021-08-20
Peripheral blood mononuclear cells (PBMC) microbiome is not affected by colon microbiota in healthy goats
Pena-Cearra, A;Belanche, A;Gonzalez-Lopez, M;Lavin, JL;Pascual-Itoiz, MA;Jimenez, E;Rodriguez, H;Aransay, AM;Anguita, J;Yanez-Ruiz, DR;Abecia, L
ANIMAL MICROBIOME
2021-04-14
Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules
Royo, F;Azkargorta, M;Lavin, JL;Clos-Garcia, M;Cortazar, AR;Gonzalez-Lopez, M;Barcena, L;del Portillo, HA;Yanez-Mo, M;Marcilla, A;Borras, FE;Peinado, H;Guerrero, I;Vales-Gomez, M;Cereijo, U;Sardon, ...
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021-01-12
Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart
Barriales, D;Martin-Ruiz, I;Carreras-Gonzalez, A;Montesinos-Robledo, M;Azkargorta, M;Iloro, I;Escobes, I;Martin-Mateos, T;Atondo, E;Palacios, A;Gonzalez-Lopez, M;Barcena, L;Cortazar, AR;Cabrera, ...
PLOS BIOLOGY
2021-01-01
The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes
Pellon, A;Barriales, D;Pena-Cearra, A;Castelo-Careaga, J;Palacios, A;Lopez, N;Atondo, E;Pascual-Itoiz, MA;Martin-Ruiz, I;Sampedro, L;Gonzalez-Lopez, M;Barcena, L;Martin-Mateos, T;Landete, JM;Prados-Rosales, ...
GUT MICROBES
2021-01-01

2020

Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with activated PI3 kinase delta syndrome (APDS2)
Ingles-Ferrandiz, M;Martin-Inaraja, M;Herrera, L;Villaverde, M;Santos, S;Vesga, MA;Garreta, E;Martin-Ruiz, I;Aransay, AM;Anguita, J;Barrena, B;Allende, LM;Gonzalez-Granado, LI;Eguizabal, C
STEM CELL RESEARCH
2020-12-01
Cross-sectional study of human coding- and non-coding RNAs in progressive stages of Helicobacter pylori infection
Lario, S;Ramirez-Lazaro, MJ;Gonzalez-Lahera, A;Lavin, JL;Vila-Casadesus, M;Quilez, ME;Brunet-Vega, A;Lozano, JJ;Aransay, AM;Calvet, X
SCIENTIFIC DATA
2020-09-08
Phosphoinositide 3-Kinase-Regulated Pericyte Maturation Governs Vascular Remodeling
Figueiredo, AM;Villacampa, P;Dieguez-Hurtado, R;Lozano, JJ;Kobialka, P;Cortazar, AR;Martinez-Romero, A;Angulo-Urarte, A;Franco, CA;Claret, M;Aransay, AM;Adams, RH;Carracedo, A;Graupera, M
CIRCULATION
2020-08-18
Variability in Cerebrospinal Fluid MicroRNAs Through Life
Prieto-Fernandez, E;Lopez-Lopez, E;Martin-Guerrero, I;Barcena, L;Gonzalez-Lopez, M;Aransay, AM;Lozano, JJ;Benito, J;Falcon-Perez, JM;Garcia-Orad, A
MOLECULAR NEUROBIOLOGY
2020-07-16
Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
Lapitz, A;Arbelaiz, A;O'Rourke, CJ;Lavin, JL;La Casta, A;Ibarra, C;Jimeno, JP;Santos-Laso, A;Izquierdo-Sanchez, L;Krawczyk, M;Perugorria, MJ;Jimenez-Aguero, R;Sanchez-Campos, A;Riano, I;Gonzalez, ...
CELLS
2020-03-14
The mitochondrial negative regulator MCJ modulates the interplay between microbiota and the host during ulcerative colitis
Pascual-Itoiz, MA;Pena-Cearra, A;Martin-Ruiz, I;Lavin, JL;Simo, C;Rodriguez, H;Atondo, E;Flores, JM;Carreras-Gonzalez, A;Tomas-Cortazar, J;Barriales, D;Palacios, A;Garcia-Canas, V;Pellon, A;Fullaondo, ...
SCIENTIFIC REPORTS
2020-01-17
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
Palomo-Irigoyen, M;Perez-Andres, E;Iruarrizaga-Lejarreta, M;Barreira-Manrique, A;Tamayo-Caro, M;Vila-Vecilla, L;Moreno-Cugnon, L;Beitia, N;Medrano, D;Fernandez-Ramos, D;Lozano, JJ;Okawa, S;Lavin, ...
JOURNAL OF CLINICAL INVESTIGATION
2020-01-15

2019

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program
Janin, M;Ortiz-Barahona, V;de Moura, MC;Martinez-Cardus, A;Llinas-Arias, P;Soler, M;Nachmani, D;Pelletier, J;Schumann, U;Calleja-Cervantes, ME;Moran, S;Guil, S;Bueno-Costa, A;Pineyro, D;Perez-Salvia, ...
ACTA NEUROPATHOLOGICA
2019-12-01
Intestinal epithelial deletion of the glucocorticoid receptor NR3C1 alters expression of inflammatory mediators and barrier function
Aranda, CJ;Arredondo-Amador, M;Ocon, B;Lavin, JL;Aransay, AM;Martinez-Augustin, O;de Medina, FS
FASEB JOURNAL : OFFICIAL PUBLICATION OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY
2019-10-26
Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes
Rodriguez, RM;Suarez-Alvarez, B;Lavin, JL;Ascension, AM;Gonzalez, M;Lozano, JJ;Raneros, AB;Bulnes, PD;Vidal-Castineira, JR;Huidobro, C;Martin-Martin, C;Sanz, AB;Ruiz-Ortega, M;Puig-Kroger, A;Corbi, ...
CELL REPORTS
2019-10-22
Gut microbiome and serum metabolome analyses identify molecular biomarkers and altered glutamate metabolism in fibromyalgia
Clos-Garcia, M;Andres-Marin, N;Fernandez-Eulate, G;Abecia, L;Lavin, JL;van Liempd, S;Cabrera, D;Royo, F;Valero, A;Errazquin, N;Vega, MCG;Govillard, L;Tackett, MR;Tejada, G;Gonzalez, E;Anguita, ...
EBIOMEDICINE
2019-08-01
ANP32E, a Protein Involved in Steroid-Refractoriness in Ulcerative Colitis, Identified by a Systems Biology Approach
Loren, V;Garcia-Jaraquemada, A;Naves, JE;Carmona, X;Manosa, M;Aransay, AM;Lavin, JL;Sanchez, I;Cabre, E;Manye, J;Domenech, E
J CROHNS COLITIS
2019-03-01
A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice
Prieto-Fernandez, E;Aransay, AM;Royo, F;Gonzalez, E;Lozano, JJ;Santos-Zorrozua, B;Macias-Camara, N;Gonzalez, M;Garay, RP;Benito, J;Garcia-Orad, A;Falcon-Perez, JM
THERANOSTICS
2019-01-01

2018

CANCERTOOL: A Visualization and Representation Interface to Exploit Cancer Datasets
Cortazar, AR;Torrano, V;Martin-Martin, N;Caro-Maldonado, A;Camacho, L;Hermanova, I;Guruceaga, E;Lorenzo-Martin, LF;Caloto, R;Gomis, RR;Apaolaza, I;Quesada, V;Trka, J;Gomez-Munoz, A;Vincent, ...
CANCER RESEARCH
2018-11-01
Integrative analysis of transcriptomics and clinical data uncovers the tumor- suppressive activity of MITF in prostate cancer
Valcarcel-Jimenez, L;Macchia, A;Martin-Martin, N;Cortazar, AR;Schaub-Clerigu, A;Pujana-Vaquerizo, M;Fernandez-Ruiz, S;Lacasa-Viscasillas, I;Santos-Martin, A;Loizaga-Iriarte, A;Unda-Urzaiz, M;Hermanova, ...
CELL DEATH & DISEASE
2018-10-11
Cluster Locator, online analysis and visualization of gene clustering
Obregon, FP;Soto, P;Lavin, JL;Cortazar, AR;Barrio, R;Aransay, AM;Cantera, R
BIOINFORMATICS
2018-10-01
MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis
Fernandez-Ramos, D;Fernandez-Tussy, P;Lopitz-Otsoa, F;Gutierrez-de-Juan, V;Navasa, N;Barbier-Torres, L;Zubiete-Franco, I;Simon, J;Fernandez, AF;Arbelaiz, A;Aransay, AM;Lavin, JL;Beraza, N;Perugorria, ...
CELL DEATH & DISEASE
2018-09-20
Serum and urine extracellular vesicles contain mRNA biomarkers for primary sclerosing cholangitis (PSC) and cholangiocarcinoma (CCA)
Arbelaiz, A;Lapitz, A;Krawczyk, M;Santos-Laso, A;Lavin, JL;Perugorria, MJ;Jimenez-Aguero, R;Lacasta, A;Ibarra, C;Sanchez-Campos, A;Jimeno, JP;Gonzalez, E;Lammert, F;Marzioni, M;Macias, R;Marin, ...
JOURNAL OF HEPATOLOGY
2018-04-01
A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi
Carreras-Gonzalez, A;Navasa, N;Martin-Ruiz, I;Lavin, JL;Azkargorta, M;Atondo, E;Barriales, D;Macias-Camara, N;Pascual-Itoiz, MA;Sampedro, L;Tomas-Cortazar, J;Pena-Cearra, A;Pellon, A;Prados-Rosales, ...
EMERGING MICROBES & INFECTIONS
2018-03-07
Identification of a highly active tannase enzyme from the oral pathogen Fusobacterium nucleatum subsp polymorphum
Tomas-Cortazar, J;Plaza-Vinuesa, L;de las Rivas, B;Lavin, JL;Barriales, D;Abecia, L;Mancheno, JM;Aransay, AM;Munoz, R;Anguita, J;Rodriguez, H
MICROBIAL CELL FACTORIES
2018-02-26
PPAR delta Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth
Martin-Martin, N;Zabala-Letona, A;Fernandez-Ruiz, S;Arreal, L;Camacho, L;Castillo-Martin, M;Cortazar, AR;Torrano, V;Astobiza, I;Zuniga-Garcia, P;Ugalde-Olano, A;Loizaga-Iriarte, A;Unda, M;Valcarcel-Jimenez, ...
CANCER RESEARCH
2018-01-15
Low-dose statin treatment increases prostate cancer aggressiveness
Caro-Maldonado, A;Camacho, L;Zabala-Letona, A;Torrano, V;Fernandez-Ruiz, S;Zamacola-Bascaran, K;Arreal, L;Valcarcel-Jimenez, L;Martin-Martin, N;Flores, JM;Cortazar, AR;Zuniga-Garcia, P;Arruabarrena-Aristorena, ...
ONCOTARGET
2018-01-05
Genetic association study of dyslexia and ADHD candidate genes in a Spanish cohort: Implications of comorbid samples
Sanchez-Moran, M;Hernandez, JA;Dunabeitia, JA;Estevez, A;Barcena, L;Gonzalez-Lahera, A;Bajo, MT;Fuentes, LJ;Aransay, AM;Carreiras, M
PLOS ONE
2018-01-01

2017

Role of Aramchol in Steatohepatitis and Fibrosis in Mice
Iruarrizaga-Lejarreta, M;Varela-Rey, M;Fernandez-Ramos, D;Martinez-Arranz, I;Delgado, TC;Simon, J;Gutierrez-de Juan, V;delaCruz-Villar, L;Azkargorta, M;Lavin, JL;Mayo, R;van Liempd, SM;Aurrekoetxea, ...
HEPATOLOGY COMMUNICATIONS
2017-11-01
The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant
Tomas-Cortazar, J;Martin-Ruiz, I;Barriales, D;Pascual-Itoiz, MA;de Juan, VG;Caro-Maldonado, A;Merino, N;Marina, A;Blanco, FJ;Flores, JM;Sutherland, JD;Barrio, R;Rojas, A;Martinez-Chantar, ML;Carracedo, ...
SCIENTIFIC REPORTS
2017-09-06
A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota
Rivero-Gutierrez, B;Gamez-Belmonte, R;Suarez, MD;Lavin, JL;Aransay, AM;Olivares, M;Martinez-Augustin, O;de Medina, FS;Zarzuelo, A
MOLECULAR NUTRITION & FOOD RESEARCH
2017-08-01
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
Zabala-Letona, A(Zabala-Letona, Amaia);Arruabarrena-Aristorena, A(Arruabarrena-Aristorena, Amaia);Martin-Martin, N(Martin-Martin, Natalia);Fernandez-Ruiz, S(Fernandez-Ruiz, Sonia);Sutherland, ...
NATURE
2017-07-06
SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma
Merino-Azpitarte, M;Lozano, E;Perugorria, MJ;Esparza-Baquer, A;Erice, O;Santos-Laso, A;O'Rourke, CJ;Andersen, JB;Jimenez-Aguero, R;Lacasta, A;D'Amato, M;Briz, O;Jalan-Sakrikar, N;Huebert, ...
JOURNAL OF HEPATOLOGY
2017-07-01
Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
Alonso, C;Fernandez-Ramos, D;Varela-Rey, M;Martinez-Arranz, I;Navasa, N;Van Liempd, SM;Trueba, JLL;Mayo, R;Ilisso, CP;de Juan, VG;Iruarrizaga-Lejarreta, M;delaCruz-Villar, L;Minchole, I;Robinson, ...
GASTROENTEROLOGY
2017-05-01
A fistful of tips for a fruitful high throughput sequencing experiment
Lavin, JL;Sanchez-Moran, M;Barcena, L;Cortazar, AR;Macias-Camara, N;Gonzalez, M;Aransay, AM
BIOESSAYS : NEWS AND REVIEWS IN MOLECULAR, CELLULAR AND DEVELOPMENTAL BIOLOGY
2017-05-01
Phenotypic characteristics of aged CD4(+) CD28(null) T lymphocytes are determined by changes in the whole-genome DNA methylation pattern
Suarez-Alvarez, B;Rodriguez, RM;Schlangen, K;Raneros, AB;Marquez-Kisinousky, L;Fernandez, AF;Diaz-Corte, C;Aransay, AM;Lopez-Larrea, C
AGING CELL
2017-04-01
VerSeDa: vertebrate secretome database
Cortazar, AR;Oguiza, JA;Aransay, AM;Lavin, JL
DATABASE : THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
2017-02-24
Epigenetic Networks Regulate the Transcriptional Program in Memory and Terminally Differentiated CD8(+) T Cells
Rodriguez, RM;Suarez-Alvarez, B;Lavin, JL;Mosen-Ansorena, D;Raneros, AB;Marquez-Kisinousky, L;Aransay, AM;Lopez-Larrea, C
JOURNAL OF IMMUNOLOGY
2017-01-15
Aramchol reduces established fibrosis in MCD diet animal model
Varela-Rey, M;Fernandez-Ramos, D;Iruarrizaga-Lejarreta, M;Van Liempd, SM;DelaCruz-Villar, L;de Davalillo, SL;Martin-Ruiz, I;Aurrekoetxea, I;Buque, X;Lavin, JL;Aransay, AM;Hayardeny, L;Alonso, ...
JOURNAL OF HEPATOLOGY
2017-01-01

2016

Stratification and therapeutic potential of PML in metastatic breast cancer
Martin-Martin, N(Martin-Martin, Natalia);Piva, M(Piva, Marco);Urosevic, J(Urosevic, Jelena);Aldaz, P(Aldaz, Paula);Sutherland, JD(Sutherland, James D.);Fernandez-Ruiz, S(Fernandez-Ruiz, Sonia);Arreal, ...
NATURE COMMUNICATIONS
2016-08-01
The metabolic co-regulator PGC1 alpha suppresses prostate cancer metastasis
Torrano, V(Torrano, Veronica);Valcarcel-Jimenez, L(Valcarcel-Jimenez, Lorea);Cortazar, AR(Rosa Cortazar, Ana);Liu, XJ(Liu, Xiaojing);Urosevic, J(Urosevic, Jelena);Castillo-Martin, M(Castillo-Martin, ...
NATURE CELL BIOLOGY
2016-06-01
Transcriptomic profiling of urine extracellular vesicles reveals alterations of CDH3 in prostate cancer
Royo, F;Zuniga-Garcia, P;Torrano, V;Loizaga, A;Sanchez-Mosquera, P;Ugalde-Olano, A;Gonzalez, E;Cortazar, AR;Palomo, L;Fernandez-Ruiz, S;Lacasa-Viscasillas, I;Berdasco, M;Sutherland, JD;Barrio, ...
ONCOTARGET
2016-02-09
SOX17 REGULATES CHOLANGIOCYTE DIFFERENTIATION AND ACTS AS A TUMOUR SUPPRESSOR IN CHOLANGIOCARCINOMA
Merino-Azpitarte, M;Lozano, E;Perugorria, MJ;Erice, O;Santos-Laso, A;Jimenez-Aguero, R;LaCasta, A;Jalan-Sakrikar, N;Huebert, RC;Thelen, KM;Gradilone, S;Aransay, AM;Lavin, JL;Fernandez-Barrena, ...
JOURNAL OF HEPATOLOGY
2016-01-01

2015

PECAS: prokaryotic and eukaryotic classical analysis of secretome
Cortazar, AR;Oguiza, JA;Aransay, AM;Lavin, JL
AMINO ACIDS
2015-12-01
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves
Gomez-Sanchez, JA;Carty, L;Iruarrizaga-Lejarreta, M;Palomo-Irigoyen, M;Varela-Rey, M;Griffith, M;Hantke, J;Macias-Camara, N;Azkargorta, M;Aurrekoetxea, I;De Juan, VG;Jefferies, HBJ;Aspichueta, ...
THE JOURNAL OF CELL BIOLOGY
2015-07-06
Methodological aspects of the molecular and histological study of prostate cancer: Focus on PTEN
Ugalde-Olano, A;Egia, A;Fernandez-Ruiz, S;Loizaga-Iriarte, A;Zuniga-Garcia, P;Garcia, S;Royo, F;Lacasa-Viscasillas, I;Castro, E;Cortazar, AR;Zabala-Letona, A;Martin-Martin, N;Arruabarrena-Aristorena, ...
METHODS
2015-05-01
CHARACTERIZATION AND VALIDATION OF ANGIOGENIC GENETIC VARIANTS RELATED TO CHRONIC HEPATITIS C PROGRESSION TO HEPATOCELLULAR CARCINOMA
Lopez-Rodriguez, R;Borque-Inurrita, MJ;Hernandez-Bartolome, A;Rodriguez-Munoz, Y;Vidal-Castineira, JR;Rodrigo, L;Garcia-Samaniego, J;Madejon, A;Abad-Santos, F;Ladero, JM;de Rueda, PM;Salmeron, ...
JOURNAL OF HEPATOLOGY
2015-04-01
Regulation of the transcriptional program by DNA methylation during human alpha beta T-cell development
Rodriguez, RM;Suarez-Alvarez, B;Mosen-Ansorena, D;Garcia-Peydro, M;Fuentes, P;Garcia-Leon, MJ;Gonzalez-Lahera, A;Macias-Camara, N;Toribio, ML;Aransay, AM;Lopez-Larrea, C
NUCLEIC ACIDS RESEARCH
2015-01-30
Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation
Salazar, M;Lorente, M;Garcia-Taboada, E;Gomez, EP;Davila, D;Zuniga-Garcia, P;Flores, JM;Rodriguez, A;Hegedus, Z;Mosen-Ansorena, D;Aransay, AM;Hernandez-Tiedra, S;Lopez-Valero, I;Quintanilla, ...
CELL DEATH AND DIFFERENTIATION
2015-01-01
TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling
Salazar, M;Lorente, M;Garcia-Taboada, E;Gomez, EP;Davila, D;Zuniga-Garcia, P;Flores, JM;Rodriguez, A;Hegedus, Z;Mosen-Ansorena, D;Aransay, AM;Hernandez-Tiedra, S;Lopez-Valero, I;Quintanilla, ...
MOLECULAR & CELLULAR ONCOLOGY
2015-01-01
Single-Cell Genome and Transcriptome Processing Prior to High-Throughput Sequencing
Aransay, AM;Barcena, L;Gonzalez-Lahera, A;Macias-Camara, N
METHODS IN MOLECULAR BIOLOGY
2015-01-01

2014

Global Gene Expression Shift during the Transition from Early Neural Development to Late Neuronal Differentiation in Drosophila melanogaster
Cantera, R;Ferreiro, MJ;Aransay, AM;Barrio, R
PLOS ONE
2014-05-15
S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome
Varela-Rey, M;Iruarrizaga-Lejarreta, M;Lozano, JJ;Aransay, AM;Fernandez, AF;Lavin, JL;Mosen-Ansorena, D;Berdasco, M;Turmaine, M;Luka, Z;Wagner, C;Lu, SC;Esteller, M;Mirsky, R;Jessen, KR;Fraga, ...
NEURON
2014-03-05
seqCNA: an R package for DNA copy number analysis in cancer using high-throughput sequencing
Mosen-Ansorena, D;Telleria, N;Veganzones, S;De la Orden, V;Maestro, ML;Aransay, AM
BMC GENOMICS
2014-03-05
A Pilot Study on the Potential of RNA-Associated to Urinary Vesicles as a Suitable Non-Invasive Source for Diagnostic Purposes in Bladder Cancer
Perez, A;Loizaga, A;Arceo, R;Lacasa, I;Rabade, A;Zorroza, K;Mosen-Ansorena, D;Gonzalez, E;Aransay, AM;Falcon-Perez, JM;Unda-Urzaiz, M;Royo, F
CANCERS
2014-03-01
SECRETOOL: integrated secretome analysis tool for fungi
Cortazar, AR;Aransay, AM;Alfaro, M;Oguiza, JA;Lavin, JL
AMINO ACIDS
2014-02-01

2013

Whole Transcriptome Analysis of Acinetobacter baumannii Assessed by RNA-Sequencing Reveals Different mRNA Expression Profiles in Biofilm Compared to Planktonic Cells
Rumbo-Feal, S;Gomez, MJ;Gayoso, C;Alvarez-Fraga, L;Cabral, MP;Aransay, AM;Rodriguez-Ezpeleta, N;Fullaondo, A;Valle, J;Tomas, M;Bou, G;Poza, M
PLOS ONE
2013-08-30
Transcriptome of Extracellular Vesicles Released by Hepatocytes
Royo, F;Schlangen, K;Palomo, L;Gonzalez, E;Conde-Vancells, J;Berisa, A;Aransay, AM;Falcon-Perez, JM
PLOS ONE
2013-07-11
Meeting report of the European mouse complex genetics network SYSGENET
Delprato, A;Aransay, AM;Kollmus, H;Schughart, K;Falcon-Perez, JM
MAMMALIAN GENOME
2013-06-01
Genetic study confirms association of HLA-DPA1*01:03 subtype with ankylosing spondylitis in HLA-B27-positive populations
Diaz-Pena, R;Castro-Santos, P;Aransay, AM;Bruges-Armas, J;Pimentel-Santos, FM;Lopez-Larrea, C
HUMAN IMMUNOLOGY
2013-06-01
Bivariate segmentation of SNP-array data for allele-specific copy number analysis in tumour samples
Mosen-Ansorena, D;Aransay, AM
BMC BIOINFORMATICS
2013-03-05
Solute Carrier Family 2 Member 1 Is Involved in the Development of Nonalcoholic Fatty Liver Disease
Vazquez-Chantada, M;Gonzalez-Lahera, A;Martinez-Arranz, I;Garcia-Monzon, C;Regueiro, MM;Garcia-Rodriguez, JL;Schlangen, KA;Mendibil, I;Rodriguez-Ezpeleta, N;Lozano, JJ;Banasik, K;Justesen, JM;Joergensen, ...
HEPATOLOGY
2013-02-01

2012

Whole transcriptome analysis of a reversible neurodegenerative process in Drosophila reveals potential neuroprotective genes
Ferreiro, MJ;Rodriguez-Ezpeleta, N;Perez, C;Hackenberg, M;Aransay, AM;Barrio, R;Cantera, R
BMC GENOMICS
2012-09-15
Hepatoma Cells From Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1
Martinez-Lopez, N;Garcia-Rodriguez, JL;Varela-Rey, M;Gutierrez, V;Fernandez-Ramos, D;Beraza, N;Aransay, AM;Schlangen, K;Lozano, JJ;Aspichueta, P;Luka, Z;Wagner, C;Evert, M;Calvisi, DF;Lu, SC;Mato, ...
GASTROENTEROLOGY
2012-09-01
Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data
Mosen-Ansorena, D;Aransay, AM;Rodriguez-Ezpeleta, N
BMC BIOINFORMATICS
2012-08-07
microRNA profiling in duodenal ulcer disease caused by Helicobacter pylori infection in a Western population
Lario, S.; Ramirez-Lazaro, M. J.; Aransay, A. M.; Lozano, J. J.; Montserrat, A.; Casalots, A.; Junquera, F.; Alvarez, J.; Segura, F.; Campo, R.; Calvet, X.
CLINICAL MICROBIOLOGY AND INFECTION
2012-08-01
A high density SNP genotyping approach within the 19q13 chromosome region identifies an association of a CNOT3 polymorphism with ankylosing spondylitis
Diaz-Pena, R;Aransay, AM;Suarez-Alvarez, B;Bruges-Armas, J;Rodriguez-Ezpeleta, N;Regueiro, M;Pimentel-Santos, FM;Mulero, J;Sanchez, A;Collantes, E;Queiro, R;Ballina, J;Alves, H;Lopez-Larrea, ...
ANNALS OF THE RHEUMATIC DISEASES
2012-05-01
The RNA-Binding Protein Human Antigen R Controls Global Changes in Gene Expression during Schwann Cell Development
Iruarrizaga-Lejarreta, M;Varela-Rey, M;Lozano, JJ;Fernandez-Ramos, D;Rodriguez-Ezpeleta, N;Embade, N;Lu, SC;van der Kraan, PM;Davidson, ENB;Gorospe, M;Mirsky, R;Jessen, KR;Aransay, AM;Mato, ...
JOURNAL OF NEUROSCIENCE
2012-04-04
Sp1 Transcription Factor Interaction with Accumulated Prelamin A Impairs Adipose Lineage Differentiation in Human Mesenchymal Stem Cells: Essential Role of Sp1 in the Integrity of Lipid Vesicles
de Eguino, GR;Infante, A;Schlangen, K;Aransay, AM;Fullaondo, A;Soriano, M;Garcia-Verdugo, JM;Martin, AG;Rodriguez, CI
STEM CELLS TRANSLATIONAL MEDICINE
2012-04-01

2011

Fine Mapping of a Major Histocompatibility Complex in Ankylosing Spondylitis Association of the HLA-DPA1 and HLA-DPB1 Regions
Diaz-Pena, R;Aransay, AM;Bruges-Armas, J;Lopez-Vazquez, A;Rodriguez-Ezpeleta, N;Mendibil, I;Sanchez, A;Torre-Alonso, JC;Bettencourt, BF;Mulero, J;Collantes, E;Lopez-Larrea, C
ARTHRITIS AND RHEUMATISM
2011-11-01
miRanalyzer: an update on the detection and analysis of microRNAs in high-throughput sequencing experiments
Hackenberg, M;Rodriguez-Ezpeleta, N;Aransay, AM
NUCLEIC ACIDS RESEARCH
2011-07-01
Distinct Roles for Wnt-4 and Wnt-11 During Retinoic Acid-Induced Neuronal Differentiation
Elizalde, C;Campa, VM;Caro, M;Schlangen, K;Aransay, AM;dM Vivanco, M;Kypta, RM
STEM CELLS
2011-01-01

2010

High-density SNP genotyping detects homogeneity of Spanish and French Basques, and confirms their genomic distinctiveness from other European populations
Rodriguez-Ezpeleta, N;Alvarez-Busto, J;Imaz, L;Regueiro, M;Azcarate, MN;Bilbao, R;Iriondo, M;Gil, A;Estonba, A;Aransay, AM
HUMAN GENETICS
2010-07-01

2009

Exploring the diabetogenicity of the HLA-B18-DR3 CEH: independent association with T1D genetic risk close to HLA-DOA
Santin, I;Castellanos-Rubio, A;Aransay, AM;Gutierrez, G;Gaztambide, S;Rica, I;Vicario, JL;Noble, JA;Castano, L;Bilbao, JR
GENES AND IMMUNITY
2009-09-01
miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments
Hackenberg, M;Sturm, M;Langenberger, D;Falcon-Perez, JM;Aransay, AM
NUCLEIC ACIDS RESEARCH
2009-07-01
Genetic Diversity of Toscana Virus
Collao, X;Palacios, G;Sanbonmatsu-Gamez, S;Perez-Ruiz, M;Negredo, AI;Navarro-Mari, JM;Grandadam, M;Aransay, AM;Lipkin, WI;Tenorio, A;Sanchez-Seco, MP
EMERGING INFECTIOUS DISEASES
2009-04-01
Association between synapsin III gene promoter SNPs and multiple sclerosis in Basque patients
Otaegui, D;Zuriarrain, O;Castillo-Trivino, T;Aransay, AM;Ruiz-Martinez, J;Olaskoaga, J;Marti-Masso, JF;de Munain, AL
MULTIPLE SCLEROSIS
2009-01-01

2008

No evidence in a large UK collection for celiac disease risk variants reported by a Spanish study - Reply
Castellanos-Rubio, A;Martin-Pagola, A;Santin, I;Castano, L;Vitoria, JC;Bilbao, JR;Aransay, AM;Castano, L;Vitoria, JC;Bilbao, JR
GASTROENTEROLOGY
2008-05-01
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice
Martinez-Chantar, ML;Vazquez-Chantada, M;Ariz, U;Martinez, N;Varela, M;Luka, Z;Capdevila, A;Rodriguez, J;Aransay, AM;Matthiesen, R;Yang, H;Calvisi, DF;Esteller, M;Fraga, M;Lu, SC;Wagner, C;Mato, ...
HEPATOLOGY
2008-04-01
The functional R620W variant of the PTPN22 gene is associated with celiac disease
Santin, I;Castellanos-Rubio, A;Aransay, AM;Castano, L;Vitoria, JC;Bilbao, JR
TISSUE ANTIGENS
2008-03-01
Combined functional and positional gene information for the identification of susceptibility variants in celiac disease
Castellanos-Rubio, A;Martin-Pagola, A;Santin, I;Hualde, I;Aransay, AM;Castano, L;Vitoria, JC;Bilbao, JR
GASTROENTEROLOGY
2008-03-01

2007

ITGA4 polymorphisms and susceptibility to multiple sclerosis
O'Doherty, C;Roos, IM;Antiguedad, A;Aransay, AM;Hillert, J;Vandenbroeck, K
JOURNAL OF NEUROIMMUNOLOGY
2007-09-01

2006

Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease
Bilbao, JR;Calvo, B;Aransay, AM;Martin-Pagola, A;de Nanclares, GP;Aly, TA;Rica, I;Vitoria, JC;Gaztambide, S;Noble, J;Fain, PR;Awdeh, ZL;Alper, CA;Castano, L
GENES AND IMMUNITY
2006-10-01
Latest Publications

Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

Lozano-Ruiz, B;Tzoumpa, A;Martinez-Cardona, C;Moreno, D;Aransay, AM;Cortazar, AR;Pico, J;Peiro, G;Lozano, J;Zapater, P;Frances, R;Gonzalez-Navajas, JM

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2022-02-01

Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

Zhang, IW;Curto, A;Lopez-Vicario, C;Casulleras, M;Duran-Guell, M;Flores-Costa, R;Colsch, B;Aguilar, F;Aransay, AM;Lozano, JJ;Hernandez-Tejero, M;Toapanta, D;Fernandez, J;Arroyo, V;Claria, J

JOURNAL OF HEPATOLOGY

2022-01-01

Identification of proximal SUMO-dependent interactors using SUMO-ID

Barroso-Gomila, O;Trulsson, F;Muratore, V;Canosa, I;Merino-Cacho, L;Cortazar, AR;Perez, C;Azkargorta, M;Iloro, I;Carracedo, A;Aransay, AM;Elortza, F;Mayor, U;Vertegaal, ACO;Barrio, R;Sutherland, ...

NATURE COMMUNICATIONS

2021-11-18

SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes

Giordano, I;Pirone, L;Muratore, V;Landaluze, E;Perez, C;Lang, V;Garde-Lapido, E;Gonzalez-Lopez, M;Barroso-Gomila, O;Vertegaal, ACO;Aransay, AM;Rodriguez, JA;Rodriguez, MS;Sutherland, JD;Barrio, ...

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2021-09-21

Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients

Rodriguez, RM;Hernandez-Fuentes, MP;Corte-Iglesias, V;Saiz, ML;Lozano, JJ;Cortazar, AR;Mendizabal, I;Suarez-Fernandez, ML;Coto, E;Lopez-Vazquez, A;Diaz-Corte, C;Aransay, AM;Lopez-Larrea, C;Suarez-Alvarez, ...

FRONTIERS IN IMMUNOLOGY

2021-08-20

Peripheral blood mononuclear cells (PBMC) microbiome is not affected by colon microbiota in healthy goats

Pena-Cearra, A;Belanche, A;Gonzalez-Lopez, M;Lavin, JL;Pascual-Itoiz, MA;Jimenez, E;Rodriguez, H;Aransay, AM;Anguita, J;Yanez-Ruiz, DR;Abecia, L

ANIMAL MICROBIOME

2021-04-14

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules

Royo, F;Azkargorta, M;Lavin, JL;Clos-Garcia, M;Cortazar, AR;Gonzalez-Lopez, M;Barcena, L;del Portillo, HA;Yanez-Mo, M;Marcilla, A;Borras, FE;Peinado, H;Guerrero, I;Vales-Gomez, M;Cereijo, U;Sardon, ...

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2021-01-12

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

Barriales, D;Martin-Ruiz, I;Carreras-Gonzalez, A;Montesinos-Robledo, M;Azkargorta, M;Iloro, I;Escobes, I;Martin-Mateos, T;Atondo, E;Palacios, A;Gonzalez-Lopez, M;Barcena, L;Cortazar, AR;Cabrera, ...

PLOS BIOLOGY

2021-01-01

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes

Pellon, A;Barriales, D;Pena-Cearra, A;Castelo-Careaga, J;Palacios, A;Lopez, N;Atondo, E;Pascual-Itoiz, MA;Martin-Ruiz, I;Sampedro, L;Gonzalez-Lopez, M;Barcena, L;Martin-Mateos, T;Landete, JM;Prados-Rosales, ...

GUT MICROBES

2021-01-01

Generation, establishment and characterization of a pluripotent stem cell line (CVTTHi001-A) from primary fibroblasts isolated from a patient with activated PI3 kinase delta syndrome (APDS2)

Ingles-Ferrandiz, M;Martin-Inaraja, M;Herrera, L;Villaverde, M;Santos, S;Vesga, MA;Garreta, E;Martin-Ruiz, I;Aransay, AM;Anguita, J;Barrena, B;Allende, LM;Gonzalez-Granado, LI;Eguizabal, C

STEM CELL RESEARCH

2020-12-01