PhD Position at the Synthetic Biology Lab

2026/01/12

CIC bioGUNE is looking for highly-motivated early stage researcher to work in the ERC Synergy project RGNcestry: Tracing and harnessing the ancestry of RNA-guided nucleases, funded by the European Commission. We are seeking candidates for a PhD position in structural biology and molecular evolution, focusing on the study of ancestral RNA-guided nucleases (RGNs). The successful candidate will contribute to experimental and structural characterization of these proteins and participate in dissemination activities linked to the project. The candidate will be part of a consortium including Botnar Institute for Immune Engineering (Switzerland), Columbia University (USA), Biofisika Institute (Spain), and CIC bioGUNE (Spain). Active participation in consortium activities such as research, meetings, training, dissemination, and outreach is expected.

Postdoctoral Researcher at the Synthetic Biology laboratory

2026/01/12

CIC bioGUNE is looking for highly-motivated postdoctoral researcher to work in the ERC Synergy project RGNcestry: Tracing and harnessing the ancestry of RNA-guided nucleases, funded by the European Commission. We are seeking candidates to fill two postdoctoral positions in ancestral sequence reconstruction and molecular evolution, combining computational phylogenetics with experimental laboratory validation. The successful candidate will contribute to the reconstruction of ancestral RNA-guided nucleases (RGNs) from large sequence datasets and perform laboratory experiments to characterize their evolutionary properties and functional roles. The candidates will be part of a consortium including Botnar Institute for Immune Engineering (Switzerland), Columbia University (USA), Biofisika Institute (Spain), and CIC bioGUNE (Spain). Active participation in consortium activities (research, meetings, dissemination, student guidance) is expected.

Postdoctoral Researcher at the Synthetic Biology laboratory

2026/01/12

CIC bioGUNE is looking for highly-motivated postdoctoral researcher to work in the ERC Synergy project RGNcestry: Tracing and harnessing the ancestry of RNA-guided nucleases, funded by the European Commission. We are seeking candidates to fill a postdoctoral position in experimental biochemistry and molecular biotechnology, with a focus on the characterization of ancestral RNA-guided nucleases (RGNs) reconstructed through ancestral sequence reconstruction. The successful candidate will investigate enzymatic properties, PAM flexibility, substrate promiscuity, and collateral cleavage activity, contributing to the development of next-generation genome editing and diagnostic tools. The candidates will be part of a consortium including Botnar Institute for Immune Engineering (Switzerland), Columbia University (USA), Biofisika Institute (Spain), and CIC bioGUNE (Spain). Active participation in consortium activities (research, meetings, dissemination, student guidance) is expected.