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Group Leader
Juan Anguita
Ikerbasque Research Professor SPECIALIST -
Itziar Fernández Domínguez
TECHNICIANS / DOCTORAL CANDIDATES -
Leticia Sampedro de la Fuente
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Adrián Iturriaga Sámano
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Nahia Del Teso
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Iker Rodríguez Bolaños
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Ion Iñaki Zendoia Beaumont
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Estíbaliz Atondo Gondra
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Ainhoa Otero Garcia
Members
Latest Publications
Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation
Peña-Cearra, A; Palacios, A; Pellon, A; Castelo, J; Pasco, ST; Seoane, I; Barriales, D; Martin, JE; Pascual-Itoiz, MA; Gonzalez-Lopez, M; Martín-Ruiz, I; Macías-Cámara, N; Gutiez, N; Araujo-Aris, ...
COMMUNICATIONS BIOLOGY
2024-02-16
Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis
Peña-Cearra, A; Castelo, J; Lavín, JL; Gonzalez-Lopez, M; Pascual-Itoiz, MA; Fuertes, M; de Juan, VG; Bárcena, L; Martín-Ruiz, I; Pellón, A; Seoane, I; Barriales, D; Palacios, A; Fullaondo, ...
GUT MICROBES
2023-12-18
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
Pena-Cearra, A; Song, DG; Castelo, J; Palacios, A; Lavin, JL; Azkargorta, M; Elortza, F; Fuertes, M; Pascual-Itoiz, MA; Barriales, D; Martin-Ruiz, I; Fullaondo, A; Aransay, AM; Rodriguez, H; ...
NPJ BIOFILMS AND MICROBIOMES
2023-10-07
An in vitro analysis of the interaction between infliximab and granulocyte-monocyte apheresis.
Rodriguez-Lago, Iago; Abecia, Leticia; Seoane, Iratxe; Anguita, Juan; Cabriada, Jose Luis;
Gastroenterologia y hepatologia
2023-07-06
Immunization with a small fragment of the Schmallenberg virus nucleoprotein highly conserved across the Orthobunyaviruses of the Simbu serogroup reduces viremia in SBV challenged IFNAR-/- mice
Guerra, GS; Barriales, D; Lorenzo, G; Moreno, S; Anguita, J; Brun, A; Abrescia, NGA;
VACCINE
2023-05-12
The Ixodes ricinus salivary gland proteome during feeding and B. Afzelii infection: New avenues for an anti-tick vaccine
Klouwens, MJ; Trentelman, JJA; Barriales, D; Ersoz, JI; Azkargorta, M; Elortza, F; Síma, R; Hajdusek, O; Cortazar, JT; Corcuera, IE; Colstrup, E; Nayak, A; Ruíz, IM; Rodriguez, H; Nijhof, AM; ...
VACCINE
2023-03-04
Development of synthetic, self-adjuvanting, and self-assembling anticancer vaccines based on a minimal saponin adjuvant and the tumor-associated MUC1 antigen
Pifferi, C; Aguinagalde, L; Ruiz-de-Angulo, A; Sacristán, N; Baschirotto, PT; Poveda, A; Jiménez-Barbero, J; Anguita, J; Fernández-Tejada, A;
CHEMICAL SCIENCE
2023-03-01
New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants
Romerio, A; Gotri, N; Franco, AR; Artusa, V; Shaik, MM; Pasco, ST; Atxabal, U; Matamoros-Recio, A; Mínguez-Toral, M; Zalamea, JD; Franconetti, A; Abrescia, NGA; Jimenez-Barbero, J; Anguita, ...
JOURNAL OF MEDICINAL CHEMISTRY
2023-02-23
Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development
Rana, VS; Kitsou, C; Dutta, S; Ronzetti, MH; Zhang, M; Bernard, Q; Smith, AA; Tomás-Cortázar, J; Yang, XL; Wu, MJ; Kepple, O; Li, WZ; Dwyer, JE; Matias, J; Baljinnyam, B; Oliver, JD; Rajeevan, ...
SCIENCE
2023-01-12
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage
González-Recio, I; Simón, J; Goikoetxea-Usandizaga, N; Serrano-Maciá, M; Mercado-Gómez, M; Rodríguez-Agudo, R; Lachiondo-Ortega, S; Gil-Pitarch, C; Fernández-Rodríguez, C; Castellana, D; Latasa, ...
NATURE COMMUNICATIONS
2022-11-25
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Juárez-Fernández, M; Goikoetxea-Usandizaga, N; Porras, D; García-Mediavilla, MV; Bravo, M; Serrano-Maciá, M; Simón, J; Delgado, TC; Lachiondo-Ortega, S; Martínez-Flórez, S; Lorenzo, O; Rincón, ...
HEPATOLOGY
2022-09-12
Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis
Peña-Cearra, A; Pascual-Itoiz, MA; Lavin, JL; Fuertes, M; Martín-Ruiz, I; Castelo, J; Palacios, A; Barriales, D; Fullaondo, A; Aransay, AM; Rodríguez, H; Anguita, J; Abecia, L;
SCIENTIFIC REPORTS
2022-06-15
Novel Oxime-Derivatized Synthetic Triterpene Glycosides as Potent Saponin Vaccine Adjuvants
Fuentes, R; Aguinagalde, L; Pifferi, C; Plata, A; Sacristan, N; Castellana, D; Anguita, J; Fernandez-Tejada, A;
FRONTIERS IN IMMUNOLOGY
2022-05-06
Resazurin-based high-throughput screening method for the discovery of dietary phytochemicals to target microbial transformation of l-carnitine into trimethylamine, a gut metabolite associated with cardiovascular disease
Simó, C; Fornari, T; García-Risco, MR; Peña-Cearra, A; Abecia, L; Anguita, J; Rodríguez, H; García-Cañas, V;
FOOD & FUNCTION
2022-04-12
Structural Analysis of the Black-Legged Tick Saliva Protein Salp15
Chaves-Arquero, B; Persson, C; Merino, N; Tomás-Cortazar, J; Rojas, AL; Anguita, J; Blanco, FJ;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2022-03-01
Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Goikoetxea-Usandizaga, N; Serrano-Maciá, M; Delgado, TC; Simón, J; Ramos, DF; Barriales, D; Cornide, ME; Jiménez, M; Pérez-Redondo, M; Lachiondo-Ortega, S; Rodríguez-Agudo, R; Bizkarguenaga, ...
HEPATOLOGY
2021-12-15
Uneven metabolic and lipidomic profiles in recovered COVID-19 patients as investigated by plasma NMR metabolomics
Bizkarguenaga, M; Bruzzone, C; Gil-Redondo, R; SanJuan, I; Martin-Ruiz, I; Barriales, D; Palacios, A; Pasco, ST; González-Valle, B; Laín, A; Herrera, L; Azkarate, A; Vesga, MA; Eguizabal, C; ...
NMR IN BIOMEDICINE
2021-10-27
A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance
Mancheño, JM; Atondo, E; Tomás-Cortázar, J; Lavín, JL; Plaza-Vinuesa, L; Martín-Ruiz, I; Barriales, D; Palacios, A; Navo, CD; Sampedro, L; Peña-Cearra, A; Pascual-Itoiz, MA; Castelo, J; Carreras-González, ...
MICROBIAL BIOTECHNOLOGY
2020-12-18
BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis
Tomás-Cortázar, J; Bossi, L; Quinn, C; Reynolds, CJ; Butler, DK; Corcoran, N; Murchú, MO; McMahon, E; Singh, M; Rongkard, P; Anguita, J; Blanco, A; Dunachie, SJ; Altmann, D; Boyton, RJ; Arnold, ...
FRONTIERS IN IMMUNOLOGY
2021-12-13
Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage
Guruceaga, X; Perez-Cuesta, U; Pellon, A; Cendon-Sanchez, S; Pelegri-Martinez, E; Gonzalez, O; Hernando, FL; Mayayo, E; Anguita, J; Alonso, RM; Keller, NP; Ramirez-Garcia, A; Rementeria, A;
JOURNAL OF FUNGI
2021-11-01