Malu Martínez-Chantar
mlmartinez
Malu Martínez-Chantar
PRINCIPAL INVESTIGATOR
Liver Disease Lab
Orcid:
Address: Bizkaia Science and Technology Park, building 801A, Derio (Bizkaia)

Malu Martinez Chantar has an extensive experience in the study of liver biology, particularly NAFLD, to which she has dedicated all of her professional career. She has a very high-level track of record productivity with publications in a very high-percentage of publications of the 1st decile in the category of Nature, Nature Communications, Cell Metabolism, Hepatology and Gastroenterology. Since 2005, when she initiated her laboratory as a Principal Investigator and got “tenure” at CIC bioGUNE, Spain, her  laboratory work has been continuously financially supported by government and private funding competitive sources, both national and international. Remarkably, she has been co-PI of NIH with Dr. Lu (USC, Keck School of Medicine, Los Angeles, USA) in the field of liver disease. She was one of the partners in an ambitious European project so called HEPADIP Consortium, which was created in response to the topic of the 3rd call for proposals in the EU FP6 Programme. Actually, she is the coordinator of the Traslational Area of the National Institute for the study of Liver and Gastrointestinal Diseases (CIBEREHD) and the Scientific Advisory Board of national and international centers. Finally, she is part of the select multinational group "Women in Hepatology" composed only of women, experts in the field of Hepatology, with representatives from Europe and USA.

She has also held several collaborations with Pharmaceutical companies with 5 resultant patent applications and 4 licensed products. Finally, she has maintained a closed collaboration with the company OWL Metabolomics in the development of OWLiver® Care and OWLiver®, two non-invasive assays for fatty liver screening and for NASH diagnosis.

Latest Publications

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Latest Publications

Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease

Gomez-Santos, B;de Urturi, DS;Nunez-Garcia, M;Gonzalez-Romero, F;Buque, X;Aurrekoetxea, I;de Juan, VG;Gonzalez-Rellan, MJ;Garcia-Monzon, C;Gonzalez-Rodriguez, A;Mosteiro, L;Errazti, G;Mifsut, ...

AGING CELL

2020-07-07

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

Barbier-Torres, L;Fortner, KA;Iruzubieta, P;Delgado, TC;Giddings, E;Chen, YDH;Champagne, D;Fernandez-Ramos, D;Mestre, D;Gomez-Santos, B;Varela-Rey, M;de Juan, VG;Fernandez-Tussy, P;Zubiete-Franco, ...

NATURE COMMUNICATIONS

2020-07-03

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma

Macias, RIR;Munoz-Bellvis, L;Sanchez-Martin, A;Arretxe, E;Martinez-Arranz, I;Lapitz, A;Gutierrez, ML;La Casta, A;Alonso, C;Gonzalez, LM;Avila, MA;Martinez-Chantar, ML;Castro, RE;Bujanda, L;Banales, ...

CANCERS

2020-06-01

Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

Urman, JM;Herranz, JM;Uriarte, I;Rullan, M;Oyon, D;Gonzalez, B;Fernandez-Urien, I;Carrascosa, J;Bolado, F;Zabalza, L;Arechederra, M;Alvarez-Sola, G;Colyn, L;Latasa, MU;Puchades-Carrasco, L;Pineda-Lucena, ...

CANCERS

2020-06-01

Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly

Simon, J;Nunez-Garcia, M;Fernandez-Tussy, P;Barbier-Torres, L;Fernandez-Ramos, D;Gomez-Santos, B;Buque, X;Lopitz-Otsoa, F;Goikoetxea-Usandizaga, N;Serrano-Macia, M;Rodriguez-Agudo, R;Bizkarguenaga, ...

CELL METABOLISM

2020-03-03

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.

Palomo-Irigoyen, Marta; Perez-Andres, Encarni; Iruarrizaga-Lejarreta, Marta; Barreira-Manrique, Adrian; Tamayo-Caro, Miguel; Vila-Vecilla, Laura; Moreno-Cugnon, Leire; Beitia, Nagore; Medrano, ...

journal of clinical investigation

2020-01-15

Sphingolipids in Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma: Ceramide Turnover

Simon, J;Ouro, A;Ala-Ibanibo, L;Presa, N;Delgado, TC;Martinez-Chantar, ML

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2020-01-01

Methionine Adenosyltransferase alpha 1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression

Murray, B;Peng, H;Barbier-Torres, L;Robinson, AE;Li, TWH;Fan, W;Tomasi, ML;Gottlieb, RA;Van Eyk, J;Lu, ZM;Mart?nez-Chantar, ML;Liangpunsakul, S;Skill, NJ;Mato, JM;Lu, SC

Hepatology (Baltimore, Md.)

2019-12-01

Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4

Gimenez-Mascarell, P (Gimenez-Mascarell, Paula); Oyenarte, I (Oyenarte, Iker); Gonzalez-Recio, I (Gonzalez-Recio, Irene); Fernandez-Rodriguez, C (Fernandez-Rodriguez, Carmen); Corral-Rodriguez, ...

International journal of molecular sciences

2019-12-01

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis

Lachiondo-Ortega, S (Lachiondo-Ortega, Sofia); Mercado-Gomez, M (Mercado-Gomez, Maria); Serrano-Macia, M (Serrano-Macia, Marina); Lopitz-Otsoa, F (Lopitz-Otsoa, Fernando); Salas-Villalobos, ...

Cells

2019-12-01