Mitochondrial Dysfunction: Unraveling the Elusive Biology Behind Anti-TNF Response During Ulcerative Colitis

Kioroglou, D; Peña-Cearra, A; Corraliza, AM; Seoane, I; Castelo, J; Panés, J; Gómez-Irwin, L; Rodríguez-Lago, I; de Zarate, JO; Fuertes, M; Martín-Ruiz, I; Gonzalez, M; Aransay, AM; Salas, A; ...

INFLAMMATORY BOWEL DISEASES

2025-02-13

The microbiota metabolite, phloroglucinol, confers long-term protection against inflammation

Castelo, J; Araujo-Aris, S; Barriales, D; Pasco, ST; Seoane, I; Peña-Cearra, A; Palacios, A; Simó, C; Garcia-Cañas, V; Khamwong, M; Martín-Ruiz, I; Gonzalez-Lopez, M; Barcena, L; Rodríguez, ...

GUT MICROBES

2024-12-31

Global and single-nucleotide resolution detection of 7-methylguanosine in RNA

DAmbrosi, S; García-Vílchez, R; Kedra, D; Vitali, P; Macias-Cámara, N; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Dietmann, S; Hurtado, A; Blanco, S;

RNA BIOLOGY

2024-12-31

A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

Jabalera, Y; Tascon, I; Samperio, S; Lopez-Alonso, JP; Gonzalez-Lopez, M; Aransay, AM; Abascal-Palacios, G; Beisel, CL; Ubarretxena-Belandia, I; Perez-Jimenez, R;

NATURE BIOTECHNOLOGY

2024-10-31

The PP2A regulator IER5L supports prostate cancer progression

Crespo, JR; Martín-Martín, N; Garcia-Longarte, S; Corres-Mendizabal, J; Carlevaris, O; Astobiza, I; Zabala-Letona, A; Guiu, M; Azkargorta, M; Gonzalez-Lopez, M; Macías-Cámara, N; Doan, P; Elortza, ...

CELL DEATH & DISEASE

2024-07-18

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...

CELL REPORTS

2024-03-26

Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation

Peña-Cearra, A; Palacios, A; Pellon, A; Castelo, J; Pasco, ST; Seoane, I; Barriales, D; Martin, JE; Pascual-Itoiz, MA; Gonzalez-Lopez, M; Martín-Ruiz, I; Macías-Cámara, N; Gutiez, N; Araujo-Aris, ...

COMMUNICATIONS BIOLOGY

2024-02-16

Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis

Peña-Cearra, A; Castelo, J; Lavín, JL; Gonzalez-Lopez, M; Pascual-Itoiz, MA; Fuertes, M; de Juan, VG; Bárcena, L; Martín-Ruiz, I; Pellón, A; Seoane, I; Barriales, D; Palacios, A; Fullaondo, ...

GUT MICROBES

2023-12-18

N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer

Garcia-Vilchez, R; Anazco-Guenkova, AM; López, J; Dietmann, S; Tomé, M; Jimeno, S; Azkargorta, M; Elortza, F; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Sánchez-Martín, MA; Huertas, P; Durán, ...

ONCOGENE

2023-09-02

METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer

García-Vilchez, R; Anazco-Guenkova, AM; Dietmann, S; López, J; Morón-Calvente, V; DAmbrosi, S; Nombela, P; Zamacola, K; Mendizabal, I; García-Longarte, S; Zabala-Letona, A; Astobiza, I; Fernández, ...

MOLECULAR CANCER

2023-07-29

U1A is a positive regulator of the expression of heterologous and cellular genes involved in cell proliferation and migration

Rovira, E; Moreno, B; Razquin, N; Hjerpe, R; Gonzalez-Lopez, M; Barrio, R; de los Mozos, IR; Ule, J; Pastor, F; Blazquez, L; Fortes, P;

MOLECULAR THERAPY NUCLEIC ACIDS

2022-05-25

SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes

Giordano, I; Pirone, L; Muratore, V; Landaluze, E; Pérez, C; Lang, V; Garde-Lapido, E; Gonzalez-Lopez, M; Barroso-Gomila, O; Vertegaal, ACO; Aransay, AM; Rodriguez, JA; Rodriguez, MS; Sutherland, ...

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2021-09-21

Peripheral blood mononuclear cells (PBMC) microbiome is not affected by colon microbiota in healthy goats

Peña-Cearra, A; Belanche, A; Gonzalez-Lopez, M; Lavín, JL; Pascual-Itoiz, MA; Jiménez, E; Rodríguez, H; Aransay, AM; Anguita, J; Yáñez-Ruiz, DR; Abecia, L;

ANIMAL MICROBIOME

2021-04-14

Extracellular Vesicles From Liver Progenitor Cells Downregulates Fibroblast Metabolic Activity and Increase the Expression of Immune-Response Related Molecules

Royo, F; Azkargorta, M; Lavin, JL; Clos-Garcia, M; Cortazar, AR; Gonzalez-Lopez, M; Barcena, L; del Portillo, HA; Yáñez-Mó, M; Marcilla, A; Borras, FE; Peinado, H; Guerrero, I; Vales-Gómez, ...

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

2021-01-12

The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes

Pellon, A; Barriales, D; Peña-Cearra, A; Castelo-Careaga, J; Palacios, A; Lopez, N; Atondo, E; Pascual-Itoiz, MA; Martín-Ruiz, I; Sampedro, L; Gonzalez-Lopez, M; Bárcena, L; Martín-Mateos, T; ...

GUT MICROBES

2021-01-01

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

Barriales, D; Martín-Ruiz, I; Carreras-González, A; Montesinos-Robledo, M; Azkargorta, M; Iloro, I; Escobés, I; Martín-Mateos, T; Atondo, E; Palacios, A; Gonzalez-Lopez, M; Bárcena, L; Cortázar, ...

PLOS BIOLOGY

2021-01-01

Variability in Cerebrospinal Fluid MicroRNAs Through Life

Prieto-Fernández, E; Lopez-Lopez, E; Martin-Guerrero, I; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Lozano, JJ; Benito, J; Falcón-Pérez, JM; Garcia-Orad, A;

MOLECULAR NEUROBIOLOGY

2020-07-16

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

Palomo-Irigoyen, M; Pérez-Andrés, E; Iruarrizaga-Lejarreta, M; Barreira-Manrique, A; Tamayo-Caro, M; Vila-Vecilla, L; Moreno-Cugnon, L; Beitia, N; Medrano, D; Fernández-Ramos, D; Lozano, JJ; ...

JOURNAL OF CLINICAL INVESTIGATION

2020-07-01

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes

Rodriguez, RM; Suarez-Alvarez, B; Lavín, JL; Ascensión, AM; Gonzalez, M; Lozano, JJ; Raneros, AB; Bulnes, PD; Vidal-Castiñeira, JR; Huidobro, C; Martin-Martin, C; Sanz, AB; Ruiz-Ortega, M; Puig-Kröger, ...

CELL REPORTS

2019-10-22

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

Lee, SY; Ramirez, J; Franco, M; Lectez, B; Gonzalez, M; Barrio, R; Mayor, U;

CELLULAR AND MOLECULAR LIFE SCIENCES

2014-07-01