Generation and validation of a novel multitarget small molecule in glioblastoma

Artetxe-Zurutuza, A; Iturrioz-Rodriguez, N; Elizazu, J; Toledano-Pinedo, M; Porro-Pérez, A; De Goñi, I; Elua-Pinin, A; Schäker-Hübner, L; Azkargorta, M; Elortza, F; Iriepa, I; Lòpez-Muñoz, F; ...

CELL DEATH & DISEASE

2025-04-04

Embryo-Induced Changes in the Protein Profile of Bovine Oviductal Extracellular Vesicles

Mazzarella, R; Sánchez, J; Fernandez-Fuertes, B; Egido, SG; McDonald, M; Alvarez-Barrientos, A; González, E; Falcón-Pérez, JM; Azkargorta, M; Elortza, F; González, ME; Lonergan, P; Rizos, D; ...

MOLECULAR & CELLULAR PROTEOMICS

2025-04-01

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

Merino-Cacho, L; Barroso-Gomila, O; Pozo-Rodríguez, M; Muratore, V; Guinea-Pérez, C; Serrano, A; Pérez, C; Cano-López, S; Urcullu, A; Azkargorta, M; Iloro, I; Galdeano, C; Juárez-Jiménez, J; ...

CELL COMMUNICATION AND SIGNALING

2025-02-19

The influence of amniotic membrane proteins on corneal regeneration when delivered directly or using hydrogel platforms

Basasoro, A; Mendicute, J; Rezola, M; Burgos, J; Fernández, M; Esporrín-Ubieto, D; Sonzogni, A; Calderón, M; Calafel, I; Díaz, A; De Souza, J; Aiastui, A; Azkargorta, M; Elortza, F; Vecino, ...

FRONTIERS IN MEDICINE

2025-02-18

Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

Salgueiro-Toledo, VC; Bertol, J; Gutierrez, C; Serrano-Mestre, JL; Ferrer-Luzon, N; Vázquez-Iniesta, L; Palacios, A; Pasquina-Lemonche, L; Espaillat, A; Lerma, L; Weinrick, B; Lavin, JL; Elortza, ...

ELIFE

2025-02-17

Proteomic evaluation of borosilicate hybrid sol-gel coatings with osteogenic, immunomodulatory and antibacterial properties

Romero-Gavilán, F; Cerqueira, A; García-Arnáez, I; Scalschi, L; Vicedo, B; Azkargorta, M; Elortza, F; Izquierdo, R; Gurruchaga, M; Goñi, I; Suay, J;

COLLOIDS AND SURFACES B-BIOINTERFACES

2025-02-16

Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis

de la Torre, RAMG; Vallverdú, J; Xu, ZQ; Ariño, S; Ferrer-Lorente, R; Zanatto, L; Mercado-Gómez, M; Aguilar-Bravo, B; Ruiz-Blázquez, P; Fernandez, MF; Navarro-Gascon, A; Blasco-Roset, A; Sànchez-Fernàndez-de-Landa, ...

NATURE COMMUNICATIONS

2025-02-10

Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases

Baldán-Martín, M; Azkargorta, M; Lapitz, A; Moreno, LO; Iloro, I; Fernández-Tomé, S; Arbelaiz, A; Escobes, I; Marín, AC; Bernardo, D; Bujanda, L; Bañales, JM; Elortza, F; Gisbert, JP; Chaparro, ...

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2025-01-01

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma

Elurbide, J; Colyn, L; Latasa, MU; Uriarte, I; Mariani, S; Lopez-Pascual, A; Valbuena, E; Castello-Uribe, B; Arnes-Benito, R; Adan-Villaescusa, E; Martinez-Perez, LA; Azkargorta, M; Elortza, ...

GUT

2025-01-01

Identification of the Wnt signal peptide that directs secretion on extracellular vesicles

Gurriaran-Rodriguez, U; Datzkiw, D; Radusky, LG; Esper, M; Javandoost, E; Xiao, F; Ming, H; Fisher, S; Marina, A; De Repentigny, Y; Kothary, R; Azkargorta, M; Elortza, F; Rojas, AL; Serrano, ...

SCIENCE ADVANCES

2024-12-11

Modulatory effects of CNNM4 on protein-l-isoaspartyl-O-methyltransferase repair function during alcohol-induced hepatic damage

González-Recio, I; Goikoetxea-Usandizaga, N; Rejano-Gordillo, CM; Conter, C; Agudo, RR; Serrano-Maciá, M; Zapata-Pavas, LE; Pena-Sanfelix, P; Azkargorta, M; Elortza, F; Herranz, JM; Thiery, ...

HEPATOLOGY

2024-11-19

Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties

Mendibil, U; Lópiz-Morales, Y; Arnaiz, B; Ruiz-Hernández, R; Martín, P; Di-Silvio, D; Garcia-Urquia, N; Elortza, F; Azkargorta, M; Olalde, B; Abarrategi, A;

MATERIALS TODAY BIO

2024-09-06

Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response

Arias-Mainer, C; Romero-Gavilán, F; Cerqueira, A; Peñarocha-Oltra, D; Bernabeu-Mira, JC; Elortza, F; Azkargorta, M; Gurruchaga, M; Goñi, I; Suay, J;

JOURNAL OF MATERIALS CHEMISTRY B

2024-08-02

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes

Sevilla, LM; Pons-Alonso, O; Gallego, A; Azkargorta, M; Elortza, F; Pérez, P;

CELL DEATH & DISEASE

2024-07-28

The PP2A regulator IER5L supports prostate cancer progression

Crespo, JR; Martín-Martín, N; Garcia-Longarte, S; Corres-Mendizabal, J; Carlevaris, O; Astobiza, I; Zabala-Letona, A; Guiu, M; Azkargorta, M; Gonzalez-Lopez, M; Macías-Cámara, N; Doan, P; Elortza, ...

CELL DEATH & DISEASE

2024-07-18

Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway

Gil-Pitarch, C; Serrano-Maciá, M; Simon, J; Mosca, L; Conter, C; Rejano-Gordillo, CM; Zapata-Pavas, LE; Peña-Sanfélix, P; Azkargorta, M; Rodríguez-Agudo, R; Lachiondo-Ortega, S; Mercado-Gómez, ...

CELL REPORTS MEDICINE

2024-07-16

Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems

Blanco-Doval, A; Azkargorta, M; Iloro, I; Beaskoetxea, J; Elortza, F; Barron, JR; Aldai, N;

FOOD CHEMISTRY

2024-07-01

Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions

Anitua, E; Tierno, R; Azkargorta, M; Elortza, F; Alkhraisat, MH;

BIOMOLECULES

2024-06-26

Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination

Ayuso-García, P; Sánchez-Rueda, A; Velasco-Avilés, S; Tamayo-Caro, M; Ferrer-Pinós, A; Huarte-Sebastian, C; Alvarez, V; Riobello, C; Jiménez-Vega, S; Buendia, I; Cañas-Martin, J; Fernández-Susavila, ...

SCIENCE ADVANCES

2024-04-12

SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...

CELL REPORTS

2024-03-26