0000-0001-8839-5438Félix Elortza obtained his BSc in Biology and a MSc in Biochemistry from the University of Basque Country (UPV/EHU) and continued his scientific pursuits by completing his PhD in Biochemistry and Molecular Biology from the same institution.
In 2001, Dr. Elortza joined the mass spectrometry laboratory of Prof. Peter Roepstorff at the University of Southern Denmark (SDU), to conduct post-doctoral research on proteomics of post-translationally modified proteins. This research was supervised by Dr. Ole N. Jensen.
In 2004, Dr. Elortza joined CIC bioGUNE as the Proteomics Platform Manager. This laboratory was founder and active partner of the Spanish Proteomics Core Facilities Network (ProteoRed, 2005-2020) and is member of CIBERehd platforms.
The unit fosters the development and settling of new proteomic technologies and methodologies with the aim to apply this knowledge on basic and oriented biomedical research. Over these years, various methods for protein analysis have been implemented, including MALDI-TOF analysis for peptide characterization and tissue MALDI Imaging, as well as nano-scale liquid chromatography online coupled to tandem mass spectrometry (nLC MS/MS) for post-translational modification and label-free quantification analyses.
Awards & recognitions
Among the founder members of the Spanish Proteomics Society (2004) and has recently been elected as President of SEProt (2024-2028). Postdoctoral Basque Government grant (2001).
Latest Publications
2023
-
Ibon Iloro
-
Mikel Azkargorta
TECHNICIANS / DOCTORAL CANDIDATES -
Iraide Escobes Corcuera
-
Javier Beaskoetxea Lejarzegi
Members
SPECIALISTLatest Publications
The PP2A regulator IER5L supports prostate cancer progression.
Crespo, Jana R; Martin-Martin, Natalia; Garcia-Longarte, Saioa; Corres-Mendizabal, Jon; Carlevaris, Onintza; Astobiza, Ianire; Zabala-Letona, Amaia; Guiu, Marc; Azkargorta, Mikel; Gonzalez-Lopez, ...
Cell death & disease
2024-07-18
Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway.
Gil-Pitarch, Claudia; Serrano-Macia, Marina; Simon, Jorge; Mosca, Laura; Conter, Carolina; Rejano-Gordillo, Claudia M; Zapata-Pavas, L Estefania; Pena-Sanfelix, Patricia; Azkargorta, Mikel; ...
Cell reports. Medicine
2024-07-16
Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems
Blanco-Doval, A; Azkargorta, M; Iloro, I; Beaskoetxea, J; Elortza, F; Barron, JR; Aldai, N;
FOOD CHEMISTRY
2024-07-01
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Ayuso-García, P; Sánchez-Rueda, A; Velasco-Avilés, S; Tamayo-Caro, M; Ferrer-Pinós, A; Huarte-Sebastian, C; Alvarez, V; Riobello, C; Jiménez-Vega, S; Buendia, I; Cañas-Martin, J; Fernández-Susavila, ...
SCIENCE ADVANCES
2024-04-12
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...
CELL REPORTS
2024-03-26
Characterization of preovulatory follicular fluid secretome and its effects on equine oocytes during in vitro maturation
Luis-Calero, M; Marinaro, F; Fernández-Hernández, P; Ortiz-Rodríguez, JM; Casado, JG; Pericuesta, E; Gutiérrez-Adán, A; González, E; Azkargorta, M; Conde, R; Bizkarguenaga, M; Embade, N; Elortza, ...
RESEARCH IN VETERINARY SCIENCE
2024-03-11
Enhancing the correlation between in vitro and in vivo experiments in dental implant osseointegration: investigating the role of Ca ions
Gavilán, FR; Cerqueira, A; Anitua, E; Muñoz, F; Arnáez, IG; Azkargorta, M; Elortza, F; Gurruchaga, M; Goñi, I; Suay, J; Tejero, R;
JOURNAL OF MATERIALS CHEMISTRY B
2024-02-16
Biallelic variants in SNUPN cause a limb girdle muscular dystrophy with myofibrillar-like features
Iruzubieta, P; Damborenea, A; Ioghen, M; Bajew, S; Fernandez-Torrón, R; Töpf, A; Herrero-Reiriz, A; Epure, D; Vill, K; Hernández-Laín, A; Manterola, M; Azkargorta, M; Pikatza-Menoio, O; Pérez-Fernandez, ...
BRAIN
2024-02-15
The impact of glycosylation on the structure, function, and interactions of CD14.
Quintana, Jon Imanol; Delgado, Sandra; Rabano, Miriam; Azkargorta, Mikel; Florencio-Zabaleta, Mirane; Unione, Luca; Vivanco, Maria dM; Elortza, Felix; Jimenez-Barbero, Jesus; Arda, Ana;
Glycobiology
2024-01-16
Müller glial cells located in the peripheral retina are more susceptible to high pressure: implications for glaucoma
Pereiro, X; Ruzafa, N; Azkargorta, M; Elortza, F; Acera, A; Ambrósio, AF; Santiago, AR; Vecino, E;
CELL AND BIOSCIENCE
2024-01-05
Using osteogenic medium in the in vitro evaluation of bone biomaterials: Artefacts due to a synergistic effect
Romero-Gavilán, F; García-Arnáez, I; Cerqueira, A; Arias-Mainer, C; Azkargorta, M; Elortza, F; Izquierdo, R; Gurruchaga, M; Goñi, I; Suay, J;
BIOCHIMIE
2024-01-01
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1
Rodríguez-Agudo, R; González-Recio, I; Serrano-Maciá, M; Bravo, M; Petrov, P; Blaya, D; Herranz, JM; Mercado-Gómez, M; Rejano-Gordillo, CM; Lachiondo-Ortega, S; Gil-Pitarch, C; Azkargorta, M; ...
JHEP REPORTS
2024-01-01
Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome
Lorca, C; Fernandez-Rhodes, M; Milan, JAS; Mulet, M; Elortza, F; Ramos-Miguel, A; Callado, LF; Meana, JJ; Mur, M; Batalla, I; Vilella, E; Serra, A; Gallart-Palau, X;
BIOMEDICINES
2024-01-01
Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters
Zeballos, N; Comino, N; Andrés-Sanz, D; Santiago-Arcos, J; Azkargorta, M; Elortza, F; Diamanti, E; López-Gallego, F;
ACS APPLIED MATERIALS & INTERFACES
2023-12-22
BioE3 identifies specific substrates of ubiquitin E3 ligases
Barroso-Gomila, O; Merino-Cacho, L; Muratore, V; Perez, C; Taibi, V; Maspero, E; Azkargorta, M; Iloro, I; Trulsson, F; Vertegaal, ACO; Mayor, U; Elortza, F; Polo, S; Barrio, R; Sutherland, JD; ...
NATURE COMMUNICATIONS
2023-11-23
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
Pena-Cearra, A; Song, DG; Castelo, J; Palacios, A; Lavin, JL; Azkargorta, M; Elortza, F; Fuertes, M; Pascual-Itoiz, MA; Barriales, D; Martin-Ruiz, I; Fullaondo, A; Aransay, AM; Rodriguez, H; ...
NPJ BIOFILMS AND MICROBIOMES
2023-10-07
N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
Garcia-Vilchez, R; Anazco-Guenkova, AM; López, J; Dietmann, S; Tomé, M; Jimeno, S; Azkargorta, M; Elortza, F; Bárcena, L; Gonzalez-Lopez, M; Aransay, AM; Sánchez-Martín, MA; Huertas, P; Durán, ...
ONCOGENE
2023-09-02
The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Goikoetxea-Usandizaga, N; Bravo, M; Egia-Mendikute, L; Abecia, L; Serrano-Maciá, M; Urdinguio, RG; Clos-García, M; Rodríguez-Agudo, R; Araujo-Legido, R; López-Bermudo, L; Delgado, TC; Lachiondo-Ortega, ...
HEPATOLOGY
2023-09-01
Proteomics as a tool to study the osteoimmunomodulatory role of metallic ions in a sol-gel coating
García-Arnáez, I; Romero-Gavilán, F; Cerqueira, A; Azkargorta, M; Elortza, F; Suay, J; Goñi, I; Gurruchaga, M;
JOURNAL OF MATERIALS CHEMISTRY B
2023-08-03
Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver Diseases
Gil, M; Azkargorta, M; Fuster, C; Martínez-Gómez, M; Raurell, I; Barberá, A; Pericàs, JM; Hide, D; Elortza, F; Genescà, J; Martell, M;
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023-08-01