Félix Elortza
felortza
Félix Elortza
PLATFORM MANAGER
Proteomics Platform
Address: Bizkaia Science and Technology Park, building 800, Derio (Bizkaia)

Félix Elortza obtained his BSc in Biology and a MSc in Biochemistry from the University of Basque Country (UPV/EHU) and continued his scientific pursuits by completing his PhD in Biochemistry and Molecular Biology from the same institution.

In 2001, Dr. Elortza joined the mass spectrometry laboratory of Prof. Peter Roepstorff at the University of Southern Denmark (SDU), to conduct post-doctoral research on proteomics of post-translationally modified proteins. This research was supervised by Dr. Ole N. Jensen.

In 2004, Dr. Elortza joined CIC bioGUNE as the Proteomics Platform Manager. This laboratory was founder and active partner of the Spanish Proteomics Core Facilities Network (ProteoRed, 2005-2020) and is member of CIBERehd platforms.

The unit fosters the development and settling of new proteomic technologies and methodologies with the aim to apply this knowledge on basic and oriented biomedical research. Over these years, various methods for protein analysis have been implemented, including MALDI-TOF analysis for peptide characterization and tissue MALDI Imaging, as well as nano-scale liquid chromatography online coupled to tandem mass spectrometry (nLC MS/MS) for post-translational modification and label-free quantification analyses.

Awards & recognitions
Among the founder members of the Spanish Proteomics Society (2004) and has recently been elected as President of SEProt (2024-2028). Postdoctoral Basque Government grant (2001).

Latest Publications

2024

Latest Publications

Differences in the proteomic profiles of the eutopic endometrium in patients with internal and external adenomyosis

Valdés-Bango, M; Azkargorta, M; Gracia, M; Ros, C; Rius, M; Martínez-Zamora, MA; De Guirior, C; Quintas, L; Elortza, F; Carmona, F;

PLOS GLOBAL PUBLIC HEALTH

2025-06-18

Structural and functional significance of Aedes aegypti AgBR1 flavivirus immunomodulator

Martinez-Castillo, A; Barriales, D; Azkargorta, M; Zalamea, JD; Ardá, A; Jimenez-Barbero, J; Gonzalez-Lopez, M; Aransay, AM; Marín-López, A; Fikrig, E; Elortza, F; Anguita, J; Abrescia, NGA; ...

JOURNAL OF VIROLOGY

2025-04-24

Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer

Schaub-Clerigué, A; Hermanova, I; Pintor-Rial, A; Sydorenko, M; Valcarcel-Jimenez, L; Macchia, A; Lectez, B; Garcia-Longarte, S; Fagoaga-Eugui, M; Astobiza, I; Martín-Martín, N; Zabala-Letona, ...

CELL DEATH & DISEASE

2025-04-23

Quercetin-doped sol-gel coatings on titanium implants: a promising approach for enhanced immune response and cell adhesion

Arias-Mainer, C; Romero-Gavilán, F; Cerqueira, A; Peñarocha-Oltra, D; García-Arnáez, I; Amorrotu, O; Azkargorta, M; Elortza, F; Gurruchaga, M; Goñi, I; Suay, J;

JOURNAL OF MATERIALS CHEMISTRY B

2025-04-07

Generation and validation of a novel multitarget small molecule in glioblastoma

Artetxe-Zurutuza, A; Iturrioz-Rodriguez, N; Elizazu, J; Toledano-Pinedo, M; Porro-Pérez, A; De Goñi, I; Elua-Pinin, A; Schäker-Hübner, L; Azkargorta, M; Elortza, F; Iriepa, I; Lòpez-Muñoz, F; ...

CELL DEATH & DISEASE

2025-04-04

Embryo-Induced Changes in the Protein Profile of Bovine Oviductal Extracellular Vesicles

Mazzarella, R; Sánchez, J; Fernandez-Fuertes, B; Egido, SG; McDonald, M; Alvarez-Barrientos, A; González, E; Falcón-Pérez, JM; Azkargorta, M; Elortza, F; González, ME; Lonergan, P; Rizos, D; ...

MOLECULAR & CELLULAR PROTEOMICS

2025-04-01

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

Merino-Cacho, L; Barroso-Gomila, O; Pozo-Rodríguez, M; Muratore, V; Guinea-Pérez, C; Serrano, A; Pérez, C; Cano-López, S; Urcullu, A; Azkargorta, M; Iloro, I; Galdeano, C; Juárez-Jiménez, J; ...

CELL COMMUNICATION AND SIGNALING

2025-02-19

The influence of amniotic membrane proteins on corneal regeneration when delivered directly or using hydrogel platforms

Basasoro, A; Mendicute, J; Rezola, M; Burgos, J; Fernández, M; Esporrín-Ubieto, D; Sonzogni, A; Calderón, M; Calafel, I; Díaz, A; De Souza, J; Aiastui, A; Azkargorta, M; Elortza, F; Vecino, ...

FRONTIERS IN MEDICINE

2025-02-18

Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

Salgueiro-Toledo, VC; Bertol, J; Gutierrez, C; Serrano-Mestre, JL; Ferrer-Luzon, N; Vázquez-Iniesta, L; Palacios, A; Pasquina-Lemonche, L; Espaillat, A; Lerma, L; Weinrick, B; Lavin, JL; Elortza, ...

ELIFE

2025-02-17

Proteomic evaluation of borosilicate hybrid sol-gel coatings with osteogenic, immunomodulatory and antibacterial properties

Romero-Gavilán, F; Cerqueira, A; García-Arnáez, I; Scalschi, L; Vicedo, B; Azkargorta, M; Elortza, F; Izquierdo, R; Gurruchaga, M; Goñi, I; Suay, J;

COLLOIDS AND SURFACES B-BIOINTERFACES

2025-02-16

Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis

de la Torre, RAMG; Vallverdú, J; Xu, ZQ; Ariño, S; Ferrer-Lorente, R; Zanatto, L; Mercado-Gómez, M; Aguilar-Bravo, B; Ruiz-Blázquez, P; Fernandez, MF; Navarro-Gascon, A; Blasco-Roset, A; Sànchez-Fernàndez-de-Landa, ...

NATURE COMMUNICATIONS

2025-02-10

Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases

Baldán-Martín, M; Azkargorta, M; Lapitz, A; Moreno, LO; Iloro, I; Fernández-Tomé, S; Arbelaiz, A; Escobes, I; Marín, AC; Bernardo, D; Bujanda, L; Bañales, JM; Elortza, F; Gisbert, JP; Chaparro, ...

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2025-01-01

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma

Elurbide, J; Colyn, L; Latasa, MU; Uriarte, I; Mariani, S; Lopez-Pascual, A; Valbuena, E; Castello-Uribe, B; Arnes-Benito, R; Adan-Villaescusa, E; Martinez-Perez, LA; Azkargorta, M; Elortza, ...

GUT

2025-01-01

Identification of the Wnt signal peptide that directs secretion on extracellular vesicles

Gurriaran-Rodriguez, U; Datzkiw, D; Radusky, LG; Esper, M; Javandoost, E; Xiao, F; Ming, H; Fisher, S; Marina, A; De Repentigny, Y; Kothary, R; Azkargorta, M; Elortza, F; Rojas, AL; Serrano, ...

SCIENCE ADVANCES

2024-12-11

Modulatory effects of CNNM4 on protein-l-isoaspartyl-O-methyltransferase repair function during alcohol-induced hepatic damage

González-Recio, I; Goikoetxea-Usandizaga, N; Rejano-Gordillo, CM; Conter, C; Agudo, RR; Serrano-Maciá, M; Zapata-Pavas, LE; Pena-Sanfelix, P; Azkargorta, M; Elortza, F; Herranz, JM; Thiery, ...

HEPATOLOGY

2024-11-19

Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties

Mendibil, U; Lópiz-Morales, Y; Arnaiz, B; Ruiz-Hernández, R; Martín, P; Di-Silvio, D; Garcia-Urquia, N; Elortza, F; Azkargorta, M; Olalde, B; Abarrategi, A;

MATERIALS TODAY BIO

2024-09-06

Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response

Arias-Mainer, C; Romero-Gavilán, F; Cerqueira, A; Peñarocha-Oltra, D; Bernabeu-Mira, JC; Elortza, F; Azkargorta, M; Gurruchaga, M; Goñi, I; Suay, J;

JOURNAL OF MATERIALS CHEMISTRY B

2024-08-02

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes

Sevilla, LM; Pons-Alonso, O; Gallego, A; Azkargorta, M; Elortza, F; Pérez, P;

CELL DEATH & DISEASE

2024-07-28

The PP2A regulator IER5L supports prostate cancer progression

Crespo, JR; Martín-Martín, N; Garcia-Longarte, S; Corres-Mendizabal, J; Carlevaris, O; Astobiza, I; Zabala-Letona, A; Guiu, M; Azkargorta, M; Gonzalez-Lopez, M; Macías-Cámara, N; Doan, P; Elortza, ...

CELL DEATH & DISEASE

2024-07-18

Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments

Romero-Gavilán, F; Arias-Mainer, C; Cerqueira, A; Peñarrocha-Oltra, D; Bernabeu-Mira, JC; García-Arnáez, I; Elortza, F; Muriach, M; Gurruchaga, M; Goñi, I; Suay, J;

BIOMEDICAL ENGINEERING ONLINE

2024-07-17