0000-0001-8839-5438Félix Elortza obtained his BSc in Biology and a MSc in Biochemistry from the University of Basque Country (UPV/EHU) and continued his scientific pursuits by completing his PhD in Biochemistry and Molecular Biology from the same institution.
In 2001, Dr. Elortza joined the mass spectrometry laboratory of Prof. Peter Roepstorff at the University of Southern Denmark (SDU), to conduct post-doctoral research on proteomics of post-translationally modified proteins. This research was supervised by Dr. Ole N. Jensen.
In 2004, Dr. Elortza joined CIC bioGUNE as the Proteomics Platform Manager. This laboratory was founder and active partner of the Spanish Proteomics Core Facilities Network (ProteoRed, 2005-2020) and is member of CIBERehd platforms.
The unit fosters the development and settling of new proteomic technologies and methodologies with the aim to apply this knowledge on basic and oriented biomedical research. Over these years, various methods for protein analysis have been implemented, including MALDI-TOF analysis for peptide characterization and tissue MALDI Imaging, as well as nano-scale liquid chromatography online coupled to tandem mass spectrometry (nLC MS/MS) for post-translational modification and label-free quantification analyses.
Awards & recognitions
Among the founder members of the Spanish Proteomics Society (2004) and has recently been elected as President of SEProt (2024-2028). Postdoctoral Basque Government grant (2001).
Latest Publications
2024
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Mikel Azkargorta
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Ibon Iloro
TECHNICIANS / DOCTORAL CANDIDATES -
Javier Beaskoetxea Lejarzegi
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Iraide Escobes Corcuera
Members
SPECIALISTLatest Publications
Embryo-Induced Changes in the Protein Profile of Bovine Oviductal Extracellular Vesicles
Mazzarella, R; Sánchez, J; Fernandez-Fuertes, B; Egido, SG; McDonald, M; Alvarez-Barrientos, A; González, E; Falcón-Pérez, JM; Azkargorta, M; Elortza, F; González, ME; Lonergan, P; Rizos, D; ...
MOLECULAR & CELLULAR PROTEOMICS
2025-04-01
Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome
Merino-Cacho, L; Barroso-Gomila, O; Pozo-Rodríguez, M; Muratore, V; Guinea-Pérez, C; Serrano, A; Pérez, C; Cano-López, S; Urcullu, A; Azkargorta, M; Iloro, I; Galdeano, C; Juárez-Jiménez, J; ...
CELL COMMUNICATION AND SIGNALING
2025-02-19
The influence of amniotic membrane proteins on corneal regeneration when delivered directly or using hydrogel platforms
Basasoro, A; Mendicute, J; Rezola, M; Burgos, J; Fernández, M; Esporrín-Ubieto, D; Sonzogni, A; Calderón, M; Calafel, I; Díaz, A; De Souza, J; Aiastui, A; Azkargorta, M; Elortza, F; Vecino, ...
FRONTIERS IN MEDICINE
2025-02-18
Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis
Salgueiro-Toledo, VC; Bertol, J; Gutierrez, C; Serrano-Mestre, JL; Ferrer-Luzon, N; Vázquez-Iniesta, L; Palacios, A; Pasquina-Lemonche, L; Espaillat, A; Lerma, L; Weinrick, B; Lavin, JL; Elortza, ...
ELIFE
2025-02-17
Proteomic evaluation of borosilicate hybrid sol-gel coatings with osteogenic, immunomodulatory and antibacterial properties
Romero-Gavilán, F; Cerqueira, A; García-Arnáez, I; Scalschi, L; Vicedo, B; Azkargorta, M; Elortza, F; Izquierdo, R; Gurruchaga, M; Goñi, I; Suay, J;
COLLOIDS AND SURFACES B-BIOINTERFACES
2025-02-16
Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis
de la Torre, RAMG; Vallverdú, J; Xu, ZQ; Ariño, S; Ferrer-Lorente, R; Zanatto, L; Mercado-Gómez, M; Aguilar-Bravo, B; Ruiz-Blázquez, P; Fernandez, MF; Navarro-Gascon, A; Blasco-Roset, A; Sànchez-Fernàndez-de-Landa, ...
NATURE COMMUNICATIONS
2025-02-10
Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases
Baldán-Martín, M; Azkargorta, M; Lapitz, A; Moreno, LO; Iloro, I; Fernández-Tomé, S; Arbelaiz, A; Escobes, I; Marín, AC; Bernardo, D; Bujanda, L; Bañales, JM; Elortza, F; Gisbert, JP; Chaparro, ...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2025-01-01
Identification of PRMT5 as a therapeutic target in cholangiocarcinoma
Elurbide, J; Colyn, L; Latasa, MU; Uriarte, I; Mariani, S; Lopez-Pascual, A; Valbuena, E; Castello-Uribe, B; Arnes-Benito, R; Adan-Villaescusa, E; Martinez-Perez, LA; Azkargorta, M; Elortza, ...
GUT
2025-01-01
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles
Gurriaran-Rodriguez, U; Datzkiw, D; Radusky, LG; Esper, M; Javandoost, E; Xiao, F; Ming, H; Fisher, S; Marina, A; De Repentigny, Y; Kothary, R; Azkargorta, M; Elortza, F; Rojas, AL; Serrano, ...
SCIENCE ADVANCES
2024-12-11
Modulatory effects of CNNM4 on protein-l-isoaspartyl-O-methyltransferase repair function during alcohol-induced hepatic damage
González-Recio, I; Goikoetxea-Usandizaga, N; Rejano-Gordillo, CM; Conter, C; Agudo, RR; Serrano-Maciá, M; Zapata-Pavas, LE; Pena-Sanfelix, P; Azkargorta, M; Elortza, F; Herranz, JM; Thiery, ...
HEPATOLOGY
2024-11-19
Development of bioactive solid-foam scaffolds from decellularized cartilage with chondrogenic and osteogenic properties
Mendibil, U; Lópiz-Morales, Y; Arnaiz, B; Ruiz-Hernández, R; Martín, P; Di-Silvio, D; Garcia-Urquia, N; Elortza, F; Azkargorta, M; Olalde, B; Abarrategi, A;
MATERIALS TODAY BIO
2024-09-06
Combining sandblasting and pink anodisation of Ti implants as a promising method for improving fibroblast adhesion and immune response
Arias-Mainer, C; Romero-Gavilán, F; Cerqueira, A; Peñarocha-Oltra, D; Bernabeu-Mira, JC; Elortza, F; Azkargorta, M; Gurruchaga, M; Goñi, I; Suay, J;
JOURNAL OF MATERIALS CHEMISTRY B
2024-08-02
Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes
Sevilla, LM; Pons-Alonso, O; Gallego, A; Azkargorta, M; Elortza, F; Pérez, P;
CELL DEATH & DISEASE
2024-07-28
The PP2A regulator IER5L supports prostate cancer progression
Crespo, JR; Martín-Martín, N; Garcia-Longarte, S; Corres-Mendizabal, J; Carlevaris, O; Astobiza, I; Zabala-Letona, A; Guiu, M; Azkargorta, M; Gonzalez-Lopez, M; Macías-Cámara, N; Doan, P; Elortza, ...
CELL DEATH & DISEASE
2024-07-18
Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments
Romero-Gavilán, F; Arias-Mainer, C; Cerqueira, A; Peñarrocha-Oltra, D; Bernabeu-Mira, JC; García-Arnáez, I; Elortza, F; Muriach, M; Gurruchaga, M; Goñi, I; Suay, J;
BIOMEDICAL ENGINEERING ONLINE
2024-07-17
Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Gil-Pitarch, C; Serrano-Maciá, M; Simon, J; Mosca, L; Conter, C; Rejano-Gordillo, CM; Zapata-Pavas, LE; Peña-Sanfélix, P; Azkargorta, M; Rodríguez-Agudo, R; Lachiondo-Ortega, S; Mercado-Gómez, ...
CELL REPORTS MEDICINE
2024-07-16
Comparative proteomic analysis of the changes in mare milk associated with different lactation stages and management systems
Blanco-Doval, A; Azkargorta, M; Iloro, I; Beaskoetxea, J; Elortza, F; Barron, JR; Aldai, N;
FOOD CHEMISTRY
2024-07-01
Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions
Anitua, E; Tierno, R; Azkargorta, M; Elortza, F; Alkhraisat, MH;
BIOMOLECULES
2024-06-26
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Ayuso-García, P; Sánchez-Rueda, A; Velasco-Avilés, S; Tamayo-Caro, M; Ferrer-Pinós, A; Huarte-Sebastian, C; Alvarez, V; Riobello, C; Jiménez-Vega, S; Buendia, I; Cañas-Martin, J; Fernández-Susavila, ...
SCIENCE ADVANCES
2024-04-12
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Lachiondo-Ortega, S; Rejano-Gordillo, CM; Simon, J; Lopitz-Otsoa, F; Delgado, TC; Mazan-Mamczarz, K; Goikoetxea-Usandizaga, N; Zapata-Pavas, LE; García-del Río, A; Guerra, P; Peña-Sanfélix, ...
CELL REPORTS
2024-03-26