Integrative and perturbation based analysis of the transcriptional dynamics of TGF beta/BMP system components in transition from embryonic stem cells to neural progenitors

Dries, R;Stryjewska, A;Coddens, K;Okawa, S;Notelaers, T;Birkhoff, J;Dekker, M;Verfaillie, CM;del Sol, A;Mulugeta, E;Conidi, A;Grosveld, FG;Huylebroeck, D

Stem cells (Dayton, Ohio)

2020-02-01

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis.

Palomo-Irigoyen, Marta; Perez-Andres, Encarni; Iruarrizaga-Lejarreta, Marta; Barreira-Manrique, Adrian; Tamayo-Caro, Miguel; Vila-Vecilla, Laura; Moreno-Cugnon, Leire; Beitia, Nagore; Medrano, ...

journal of clinical investigation

2020-01-15

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

Lardenoije, R;Roubroeks, JAY;Pishva, E;Leber, M;Wagner, H;Iatrou, A;Smith, AR;Smith, RG;Eijssen, LMT;Kleineidam, L;Kawalia, A;Hoffmann, P;Luck, T;Riedel-Heller, S;Jessen, F;Maier, W;Wagner, ...

CLINICAL EPIGENETICS

2019-11-27

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

Ravichandran, S;Hartmann, A;del Sol, A

Bioinformatics (Oxford, England)

2019-11-07

Assessment of network module identification across complex diseases

Choobdar, S;Ahsen, ME;Crawford, J;Tomasoni, M;Fang, T;Lamparter, D;Lin, JY;Hescott, B;Hu, XZ;Mercer, J;Natoli, T;Narayan, R;Aicheler, F;Amoroso, N;Arenas, A;Azhagesan, K;Baker, A;Banf, M;Batzoglou, ...

NATURE METHODS

2019-09-01

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects

de Soysa, TY;Ranade, SS;Okawa, S;Ravichandran, S;Huang, Y;Salunga, HT;Schricker, A;del Sol, A;Gifford, CA;Srivastava, D

NATURE

2019-08-01

An integrative method to predict signalling perturbations for cellular transitions

Zaffaroni, G;Okawa, S;Morales-Ruiz, M;del Sol, A

nucleic acids research

2019-07-09

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy

Sol, A;Okawa, S;Ravichandran, S

Trends in biotechnology

2019-07-01

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities

Okawa, S;del Sol, A

nucleic acids research

2019-04-23

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

Kalamakis, G;Brune, D;Ravichandran, S;Bolz, J;Fan, WQ;Ziebell, F;Stiehl, T;Catala-Martinez, F;Kupke, J;Zhao, S;Llorens-Bobadilla, E;Bauer, K;Limpert, S;Berger, B;Christen, U;Schmezer, P;Mallm, ...

CELL

2019-03-07