2020/02/25
UbiCODE Meeting SYMPOSIUM Writing and Editing the Ubiquitin Code UBIRed Meeting
From the 24th to the 27th of February, there will take place in Bilbao three scientific events related to the biomedical research on the post-translational modifications of proteins by the ubiquitin family, organized by CIC bioGUNE, the University of the Basque Country and the French CNRS (Centre National de la Recherche Scientifique), together with the scientific European and Spanish scientific consortiums UbiCODE, TRIM-NET and UBIRed. During these events, the most important advances in this field will be shared and discussed.
Proteins are the main effectors of the cells and they can be modified after their synthesis. Post-translational modifications by members of the ubiquitin family are at the heart of almost every biological process, including regulation of protein levels, localization, and quality control. Defects in this protein homeostasis (proteostasis) can result in developmental anomalies and disease. An intricate interplay exists among the ubiquitin-family members, with diverse chains and linkages that constitutes a “ubiquitin code”, the full meaning of which is largely unknown. Fundamental research on the ubiquitin code continues to grow, with the pharmaceutical industry taking aim at potential targets in the proteostasis area for novel therapies.
On February 24th-25th, UbiCODE will celebrate its second annual meeting. UbiCODE is a scientific consortium funded by the EU (European Training Program ETN), formed by 11 research institutions across 5 European countries and co-coordinated from CIC bioGUNE and CNRS. UbiCODE is committed to research of the ubiquitin code and on the training of 13 PhD students in this field.
“Writing and Editing the Ubiquitin Code” is a one-and-a-half day symposium on February 26th-27th that will focus on how the ubiquitin code is written and edited though ligases and proteases, how the different modifications affect cell signaling, and how new technologies can be applied to analyze these modifications. Presentations will cover a wide range of topics, like cancer, neurodegeneration and infectious diseases. The Symposium will gather more than a 100 attendants, with more than 30 oral and 40 poster presentations by international leaders in the field, as well as national and local researchers from the University of Basque Country and CIC bioGUNE. This Symposium will coincide with the second annual meeting of UBIRed, a Spanish Network of Excellence on the field of ubiquitin modifications.
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