2010/09/01

Structural Basis for the Wobbler Mouse Neurodegenerative Disorder

Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex: the GARP complex is involved in tethering endosome-derived vesicles to the trans-Golgi network. This study sheds light on two important aspects of GARP biology.


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2010/07/28

Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

Fibroblast growth factor 21 (FGF21) is a hepatic protein that plays a critical role in metabolism, stimulating...

science

2010/09/10

Mutations That Cause Neurodegenerative Disorders

Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, is a progressive neuromuscular disease that weakens and...

science