3D Bioelectronic Interfaces to Assess Cancer in vitro

 

Seminar

3D Bioelectronic Interfaces to Assess Cancer in vitro

Janire Saez

3D Bioelectronic Interfaces to Assess Cancer in vitro The generation of in vitro platforms capable of mimicking the in vivo situation as an alternative to animal models is necessary for medicine and drug discovery Electroactive poly( 3 4 ethylenedioxythiophene) polystyrene sulfonate (PEDOT PSS) porous scaffolds can be used in the generation of 3 D bioelectronics models that mimic an specific tissue with integrated electrical monitoring Microfluidic devices offer optical transparency, miniaturization, and controlled media perfusion required in organ on a chip models The interface between 3 D bioelectronics and microfluidic devices enables real time electrical and optical monitoring of cellular processes, such as cell proliferation, in a controlled microenvironment My research line focuses on the development of innovative biomimetic 3 D bioelectronic interfaces for the simultaneous optical and electrochemical monitoring of cancer cell proliferation and migration

More information in PDF