The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.
Liver Cancer, the fifth most common cancer worldwide and the third leading cause of death, is a very complex and heterogeneous pathology with multiple and distinct signaling pathways that converge in the same malignant transformation....Enter
Felipe Goñi-de-Cerio, Julie Thevenot, Hugo Oliveira, Encarnación Pérez-Andrés, Edurne Berra, Marc Masa,
Blanca Suárez-Merino, Sébastien Lecommandoux, and Pedro Heredia. J. Biomed. Nanotechnol. 11,...
The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures. This molecule is expressed in ca. 90 % of carcinomas, and there is a direct correlation between the aggressiveness of the carcinoma and...Enter
Intracellular proteolysis is critical to maintaining cellular homeostasis, and aberrations in this process play a central role in pathologies such as cancers, immune diseases and neurodegenerative conditions. The PROTEOSTASIS project aims to...Enter
PCNA forms a ring that encircles and slides on the DNA. It is an essential factor in replication and repair that recruits DNA-modifying enzymes and regulatory proteins to the replication fork. The regulatory protein p15 is...Enter
PhD PositionThe Connell and Fucini groups in the Structural Biology Unit at the CIC bioGUNE (http://www.cicbiogune.es) are seeking applicants for the Basque Government Pre-doc Fellowships call (expected to be open August 18 to September 18). The project will include biochemically and structurally characterising cellular macromolecular machines. more offers