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CIC bioGUNE

CIC bioGUNE

The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.


Research

Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin

 

Ubiquitination is behind most cellular processes, with ubiquitin substrates being regulated variously according to the number of covalently conjugated ubiquitin molecules and type of chain formed. Researchers from CIC bioGUNE, led by...

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Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase fromMycobacterium tuberculosis

 

Mycobacterium tuberculosis is a human pathogen that causes tuberculosis, a disease that kills ca. 2 million people worldwide every year. The occurrence of multidrug and extensively drug-resistant strains of M. tuberculosis have...

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Structure of a protein interaction key for microtubule elongation


Cell division involves the segregation of the genetic material into the daughter cells that, when not properly controlled, may produce aberrant chromosomes and lead to cancer. Microtubule elongation plays a key role in the machine that...

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Structure and interactions of a multifunctional domain of HuR protein


The human antigen R (HuR) is a powerful regulator of cancer. By binding and stabilizing certain messenger RNA molecules, it promotes the production of other proteins related to cell proliferation, survival, angiogenesis and metastasis, and...

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Sox2 promotes tamoxifen resistance in breast cancer cells

 

A study by the group of Maria Vivanco, in collaboration with the group of Robert Kypta (also at CIC bioGUNE), Dr Zabalza (Hospital of Galdakao) and Dr López-Ruiz (PreteImagen) has been published this week in the prestigious...

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Seminars

2015/03/27

Dimitris Xirodimas, PhD (CNRS-CRBM, Montpellier)

TBA

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