We use private and third party cookies to enhance the browsing experience. If you continue to browse by using the scrollbars, clicking on any link, or by closing the present dialogue, we understand you accept our cookie policy.

CIC bioGUNE

CIC bioGUNE

The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.


Research

Protein homeostasis project brings researchers together

Intracellular proteolysis is critical to maintaining cellular homeostasis, and aberrations in this process play a central role in pathologies such as cancers, immune diseases and neurodegenerative conditions. The PROTEOSTASIS project aims to...

Enter

The oncogenic protein p15 binds and crosses the PCNA ring, suggesting a mechanism for regulation of DNA replication and repair.

 

PCNA forms a ring that encircles and slides on the DNA. It is an essential factor in replication and repair that recruits DNA-modifying enzymes and regulatory proteins to the replication fork. The regulatory protein p15 is...

Enter

Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase fromMycobacterium tuberculosis

 

Mycobacterium tuberculosis is a human pathogen that causes tuberculosis, a disease that kills ca. 2 million people worldwide every year. The occurrence of multidrug and extensively drug-resistant strains of M. tuberculosis have...

Enter

Human Basal Tear Peptidome Characterization by CID, HCD, and ETD Followed by in Silico and in Vitro Analyses for Antimicrobial Peptide Identification.


Endogenous peptides are valuable targets in the analysis of biological processes. The tear film contains proteins and peptides released by the tear duct mucosal cells, including antimicrobial peptides involved in the protection against...

Enter

Modulating Weak Interactions for Molecular Recognition: A Dynamic Combinatorial Analysis for Assessing the Contribution of Electrostatics to the Stability of CH-pi Bonds in Water

 

The interactions between aromatic moieties and aliphatic entities are of paramount importance for essential molecular recognition events. In particular, CH-pi contacts are present in a variety of biomolecular complexes, and provide...

Enter



Seminars

2015/06/12

Prof. Santiago Rodríguez de Córdoba (Centro de Investigaciones Biologicas)

Complement genetics and susceptibility to inflammatory disease. Lessons from genotype-phenotype correlations

Prof. Santiago Rodríguez de Cordoba laboratory uses genomics and molecular biology techniques to carry out research in Human Genetics. Overall, there is a strong -long standing- interest in Complement genetics. Since 1983, their laboratory has...

Enter

News

Events