The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.
The human antigen R (HuR) is a powerful regulator of cancer. By binding and stabilizing certain messenger RNA molecules, it promotes the production of other proteins related to cell proliferation, survival, angiogenesis and metastasis, and...
PCNA forms a ring that encircles and slides on the DNA. It is an essential factor in replication and repair that recruits DNA-modifying enzymes and regulatory proteins to the replication fork. The regulatory protein p15 is...Enter
Intracellular proteolysis is critical to maintaining cellular homeostasis, and aberrations in this process play a central role in pathologies such as cancers, immune diseases and neurodegenerative conditions. The PROTEOSTASIS project aims to...Enter
The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures. This molecule is expressed in ca. 90 % of carcinomas, and there is a direct correlation between the aggressiveness of the carcinoma and...Enter
Endogenous peptides are valuable targets in the analysis of biological processes. The tear film contains proteins and peptides released by the tear duct mucosal cells, including antimicrobial peptides involved in the protection against...
Targeting bacterial cell division protein FtsZ with assembly inhibitors and fluorescent probes
2015/06/22Marie Skłodowska-Curie action awarded to carry out structure-function studies on Schmallenberg virus in the Abrescia Lab. more news
2015/06/09The barrier preventing fatal disease transmission from deer to humans is identified more news
2015/05/13A new book on the role of carbohydrates in nature, with special emphasis on their roles in disease, is available. more news