CIC bioGUNE

Research

Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD

The covalent attachment of adenosine monophosphate (AMP) to proteins, a process called AMPylation (adenylylation), has recently emerged as a novel theme in microbial pathogenesis. While AMPylases from various pathogenic microorganisms have...

Regulating the regulators: Steroid hormone synthesis is controlled by SUMO, Ftz-f1 and Scavenger Receptors.

Steroid hormones are cholesterol derivates that control many aspects of animal physiology, including development, growth, energy storage and reproduction. In insects, the main steroid hormone is ecdysone, which gets activated in pulses that precede...

Seminars

2013/06/28

Kornelius Zeth, PhD (Unidad de Biofísica-UPV)

Killing bacteria - the power of natural antibiotics

Uni- and multicellular organisms have developed smart methods to combat and kill bacteria. Many bacteria secret bacteriocins or proteins of the Cdi system to target and kill related or unrelated bacterial strains of the same culture, respectively....