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CIC bioGUNE

CIC bioGUNE

The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.


Research

The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures

 

The Tn antigen (α-O-GalNAc-Ser/Thr) is one specific human tumor-associated structures. This molecule is expressed in ca. 90 % of carcinomas, and there is a direct correlation between the aggressiveness of the carcinoma and...

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Protein homeostasis project brings researchers together

Intracellular proteolysis is critical to maintaining cellular homeostasis, and aberrations in this process play a central role in pathologies such as cancers, immune diseases and neurodegenerative conditions. The PROTEOSTASIS project aims to...

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Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

 

Liver Cancer, the fifth most common cancer worldwide and the third leading cause of death, is a very complex and heterogeneous pathology with multiple and distinct signaling pathways that converge in the same malignant transformation....

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Modulating Weak Interactions for Molecular Recognition: A Dynamic Combinatorial Analysis for Assessing the Contribution of Electrostatics to the Stability of CH-pi Bonds in Water

 

The interactions between aromatic moieties and aliphatic entities are of paramount importance for essential molecular recognition events. In particular, CH-pi contacts are present in a variety of biomolecular complexes, and provide...

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Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase fromMycobacterium tuberculosis

 

Mycobacterium tuberculosis is a human pathogen that causes tuberculosis, a disease that kills ca. 2 million people worldwide every year. The occurrence of multidrug and extensively drug-resistant strains of M. tuberculosis have...

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Seminars

2015/09/11

José Manuel Andreu, PhD (CIB-CSIC)

Targeting bacterial cell division protein FtsZ with assembly inhibitors and fluorescent probes

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News

Events