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The goal of CIC bioGUNE is to bring discoveries to the society by partnering with industry.


Cellular and molecular heterogeneity in breast cancer


Breast cancer is a very heterogeneous disease. We now know that breast tumors contain cells with properties of stem cells (cancer stem cells, CSCs) that support tumor initiation and resistance to current therapies. Furthermore, the...


Cellular Uptake and Cytotoxic Effect of Epidermal Growth Factor Receptor Targeted and Plitidepsin Loaded Co-Polymeric Polymersomes on Colorectal Cancer Cell Lines

Felipe Goñi-de-Cerio, Julie Thevenot, Hugo Oliveira, Encarnación Pérez-Andrés, Edurne Berra, Marc Masa,
Blanca Suárez-Merino, Sébastien Lecommandoux, and Pedro Heredia. J. Biomed. Nanotechnol. 11,...


Molecular processes affecting mammary luminal progenitor fate


In contrast to most mammalian organs, the mammary gland develops mostly after birth. Mammary epithelium is a bilayered structure formed by luminal and myoepithelial cells. Luminal cells are responsible for producing milk. When the...


The quest of anticancer vaccines: Deciphering the fine-epitope specificity of cancer-related monoclonal antibodies by combining microarray screening and STD-NMR

The expression of MUC1, a glycoprotein displaying complex oligosaccharides, is usually increased with aberrant glycosylation in tumour cells. In fact, the carbohydrate side chains are now incomplete and different epitopes, including the Tn antigen...


The unexplored archaeal domain and its viruses

Archaeal viruses represents one of the most challenging and yet unknown area of investigation. Archaeal viruses live in extreme environments (alkaline, acidic conditions, hyper-salinity and elevated temperature), conditions reminiscent of...




Anniversary Lecture Prof. Hagan Bayley (University of Oxford, UK)

Tissue-like materials from communicating droplet networks

Synthetic biology is being used to build devices through both top-down and bottom-up approaches. For example, genome engineering has been used to reprogram cells, and DNA origami has been used to produce a variety of nanodevices. While progress has...





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